Abstract: A decoder includes a feature extraction circuit for calculating one or more feature vectors. An acoustic model circuit is coupled to receive one or more feature vectors from and assign one or more likelihood values to the one or more feature vectors. A memory architecture that utilizes on-chip state lattices and an off-chip memory for storing states of transition of the decoder is used to reduce reading and writing to the off-chip memory. The on-chip state lattice is populated with at least one of the states of transition stored in the off-chip memory. An on-chip word is generated from a snapshot from the on-chip state lattice. The on-chip state lattice and the on-chip word lattice act as an on-chip cache to reduce reading and writing to the off-chip memory.

Abstract: A surgical instrument operable to sever tissue includes a body assembly and a selectively coupleable end effector assembly. The end effector assembly may include a transmission assembly and an end effector. The body assembly includes a trigger and a casing configured to couple with the transmission assembly. An information transmission system transmits instrument information received from a sensor, for example, to a secure server via a secure gateway connected to the instrument. The instrument may be previously tested on a calibration kit to pre-determine and load surgeon-specific settings onto the instrument prior to use.

Abstract: A decoder includes a feature extraction circuit for calculating one or more feature vectors. An acoustic model circuit is coupled to receive one or more feature vectors from and assign one or more likelihood values to the one or more feature vectors. A memory architecture that utilizes on-chip state lattices and an off-chip memory for storing states of transition of the decoder is used to reduce reading and writing to the off-chip memory. The on-chip state lattice is populated with at least one of the states of transition stored in the off-chip memory. An an on-chip word is generated from a snapshot from the on-chip state lattice. The on-chip state lattice and the on-chip word lattice act as an on-chip cache to reduce reading and writing to the off-chip memory.

Abstract: A decoder comprises a feature extraction circuit for calculating one or more feature vectors; an acoustic model circuit coupled to receive one or more feature vectors from said feature extraction circuit and assign one or more likelihood values to the one or more feature vectors; a memory for storing states of transition of the decoder; and a search circuit for receiving an input from said acoustic model circuit corresponding to the one or more likelihood values based upon the one or more feature vectors, and for choosing states of transition from the memory based on the input from said acoustic model.

Abstract: Systems and methods are provided for compressing and decompressing data in an ultrasound beamformer. The systems and methods include an encoder for compressing delay data based at least in part on a smoothness of a delay profile, and for compressing apodization data based at least in part on a smoothness of an apodization profile.

Abstract: A decoder comprises a feature extraction circuit for calculating one or more feature vectors; an acoustic model circuit coupled to receive one or more feature vectors from said feature extraction circuit and assign one or more likelihood values to the one or more feature vectors; a memory for storing states of transition of the decoder; and a search circuit for receiving an input from said acoustic model circuit corresponding to the one or more likelihood values based upon the one or more feature vectors, and for choosing states of transition from the memory based on the input from said acoustic model.

Abstract: A method of determining the immune response of a mammal to circulating tumor marker proteins is described in which a sample of bodily fluid, for example plasma or serum, is contacted with a panel of two or more distinct tumor marker antigen. The presence of complexes between the tumor marker antigens and any autoantibodies to the antigens present in the sample are detected and provide an indication of an immune response to a circulating tumor marker protein. The method is useful for the diagnosis of cancer, particularly for identifying new or recurrent cancer in an otherwise assymptomatic patient.

Abstract: A method of determining the immune response of a mammal to circulating tumour marker proteins is described in which a sample of bodily fluid, for example plasma or serum, is contacted with a panel of two or more distinct tumour marker antigen. The presence of complexes between the tumour marker antigens and any autoantibodies to the antigens present in the sample are detected and provide an indication of an immune response to a circulating tumour marker protein. The method is useful for the diagnosis of cancer, particularly for identifying new or recurrent cancer in an otherwise assymptomatic patient.

Abstract: A method of determining the immune response of a mammal to circulating tumour marker proteins is described in which a sample of bodily fluid, for example plasma or serum, is contacted with a panel of two or more distinct tumour marker antigen. The presence of complexes between the tumour marker antigens and any autoantibodies to the antigens present in the sample are detected and provide an indication of an immune response to a circulating tumour marker protein. The method is useful for the diagnosis of cancer, particularly for identifying new or recurrent cancer in an otherwise assymptomatic patient.

Abstract: A method of determining the immune response of a mammal to circulating tumour marker proteins is described in which a sample of bodily fluid, for example plasma or serum, is contacted with a panel of two or more distinct tumour marker antigens. The presence of complexes between the tumour marker antigens and any autoantibodies to the antigens present in the sample are detected and provide an indication of an immune response to a circulating tumour marker protein. The method is useful for the diagnosis of cancer, particularly for identifying new or recurrent cancer in an otherwise assymptomatic patient.

Abstract: A method of determining the immune response of a mammal to circulating tumour marker proteins is described in which a sample of bodily fluid, for example plasma or serum, is contacted with a panel of two or more distinct tumour marker antigen. The presence of complexes between the tumour marker antigens and any autoantibodies to the antigens present in the sample are detected and provide an indication of an immune response to a circulating tumour marker protein. The method is useful for the diagnosis of cancer, particularly for identifying new or recurrent cancer in an otherwise assymptomatic patient.