Patents by Inventor Michael R. Reeder

Michael R. Reeder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8426610
    Abstract: Disclosed are novel amino acid derivatives of formula (I) and (II) processes for the preparation thereof, and their use in the preparation of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino-[4,5-c]pyrrole.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: April 23, 2013
    Assignee: Merck Sharp & Dohme B.V.
    Inventors: Gerardus Johannes Kemperman, Jacobus Johannes Maria Van Der Linden, Michael R. Reeder
  • Publication number: 20110207942
    Abstract: Disclosed are novel amino acid derivatives of formula (I) and (II) processes for the preparation thereof, and their use in the preparation of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino-[4,5-c]pyrrole.
    Type: Application
    Filed: May 2, 2011
    Publication date: August 25, 2011
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Gerardus Johannes Kemperman, Jacobus Johannes Maria Van Der Linden, Michael R. Reeder
  • Patent number: 7985860
    Abstract: This application discloses a novel process to synthesize 2-(Quinolin-5yo)-4,5-Disubstituted-Azole derivatives, which may be used, for example, as PDE IV inhibitor compounds in pharmaceutical preparations.
    Type: Grant
    Filed: August 10, 2007
    Date of Patent: July 26, 2011
    Assignee: Schering Corporation
    Inventors: Timothy D. Cutarelli, Xiaoyong Fu, Timothy L. McAllister, Michael R. Reeder, Jianguo Yin, Kelvin H. Yong, Shuyi Zhang
  • Patent number: 7956202
    Abstract: Disclosed are novel amino acid derivatives of formula (I) and (II) processes for the preparation thereof, and their use in the preparation of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino-[4,5-c]pyrrole.
    Type: Grant
    Filed: December 7, 2009
    Date of Patent: June 7, 2011
    Inventors: Gerardus Johannes Kemperman, Jacobus Johannes Maria Van Der Linden, Michael R. Reeder
  • Patent number: 7919505
    Abstract: The present invention relates to the compound of the formula To methods of treating upper and lower obstructive airway diseases using said compound, to formulations comprising it, and to polymorphs and processes of synthesis of the polymorphic forms.
    Type: Grant
    Filed: July 10, 2007
    Date of Patent: April 5, 2011
    Assignee: Schering Corporation
    Inventors: Pauline C. Ting, Joe F. Lee, Kung-I Feng, Michael R. Reeder, Scott T. Trzaska, Man Zhu, Chen Mao, Dimitar L. Filipov, Dimitrios N. Zarkadas
  • Patent number: 7872147
    Abstract: Disclosed are novel amino acid derivatives of formula (I) and (II) processes for the preparation thereof, and their use in the preparation of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino-[4,5-c]pyrrole.
    Type: Grant
    Filed: April 6, 2006
    Date of Patent: January 18, 2011
    Assignee: N. V. Organon
    Inventors: Gerardus Johannes Kemperman, Jacobus Johannes Maria Van Der Linden, Michael R. Reeder
  • Publication number: 20100324295
    Abstract: The present invention relates a process for the preparation of a compound of the formula: wherein R1, R2, R6, R9 and R10 are as described herein. The compounds are inhibitors of phosphodiesterase 4 (PDE4).
    Type: Application
    Filed: July 3, 2008
    Publication date: December 23, 2010
    Inventors: Timothy D. Cutarelli, Dimitar L. Filipov, Christopher Stanley Pridgen, Michael R. Reeder, Kelvin H. Yong, Dimitrios N. Zarkadas
  • Publication number: 20100152461
    Abstract: Disclosed are novel amino acid derivatives of formula (I) and (II) processes for the preparation thereof, and their use in the preparation of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino-[4,5-c]pyrrole.
    Type: Application
    Filed: December 7, 2009
    Publication date: June 17, 2010
    Inventors: GERARDUS JOHANNES KEMPERMAN, JACOBUS JOHANNES MARIA VAN DER LINDEN, MICHAEL R. REEDER
  • Publication number: 20100099898
    Abstract: Disclosed are intermediates and processes for preparing epoxides of the formula: where R and PROT are defined herein. These epoxides are useful as intermediates in the production of biologically active compounds, i.e., in the production of pharmaceutical agents.
    Type: Application
    Filed: December 23, 2009
    Publication date: April 22, 2010
    Inventor: Michael R. Reeder
  • Patent number: 7638646
    Abstract: Disclosed are intermediates and processes for preparing epoxides of the formula: where R and PROT are defined herein. These epoxides are useful as intermediates in the production of biologically active compounds, i.e., in the production of pharmaceutical agents.
    Type: Grant
    Filed: February 1, 2005
    Date of Patent: December 29, 2009
    Assignee: Elan Pharmaceuticals Inc.
    Inventor: Michael R. Reeder
  • Patent number: 7115747
    Abstract: Disclosed are compounds of formula III and a process to prepare a compound of formula III wherein R1, R2, R3 and R6 are defined herein, using a zinc chloride/optionally substituted oxazole adduct and an compound of formula I. Further disclosed are methods of using compounds of formula III to prepare compounds useful in the treatment of Alzheimer's disease and related conditions.
    Type: Grant
    Filed: June 20, 2003
    Date of Patent: October 3, 2006
    Assignee: Pharmacia & Upjohn Company
    Inventors: Michael R. Reeder, Rick J. Imbordino
  • Patent number: 6849750
    Abstract: Disclosed are intermediates and processes for preparing epoxides of the formula: where R and PROT are defined herein. These epoxides are useful as intermediates in the production of biologically active compounds, i.e., in the production of pharmaceutical agents.
    Type: Grant
    Filed: April 23, 2002
    Date of Patent: February 1, 2005
    Assignee: Pharmacia & UpJohn Company LLC
    Inventor: Michael R. Reeder
  • Publication number: 20040063965
    Abstract: Disclosed are compounds of formula III and a process to prepare a compound of formula III 1
    Type: Application
    Filed: June 20, 2003
    Publication date: April 1, 2004
    Inventors: Michael R. Reeder, Rick J. Imbordino
  • Publication number: 20030004360
    Abstract: Disclosed are intermediates and processes for preparing epoxides of the formula: 1
    Type: Application
    Filed: April 23, 2002
    Publication date: January 2, 2003
    Inventor: Michael R. Reeder
  • Patent number: 5759876
    Abstract: An antifuse includes a metal cap layer located at the second barrier layer of the antifuse to improve the antifuse yield and long term reliability. An antifuse further includes one or more interfacial oxide film layers surrounding an antifuse dielectric layer to provide narrowing of the antifuse programming voltage distribution and to further improve the antifuse yield and long term reliability.
    Type: Grant
    Filed: November 1, 1995
    Date of Patent: June 2, 1998
    Assignee: United Technologies Corporation
    Inventors: Scott G. Singlevich, Bradley S. Holway, Kurt D. Humphrey, Brian Scott Poarch, Michael R. Reeder, Neal J. Verzwyvelt
  • Patent number: 4835118
    Abstract: A process of manufacturing selectively restructurable conductive links between circuit elements and corresponding spare elements on a semiconductor. A continuous green light laser directed at a non-conductive amorphous region in the links causes the region to recrystallize. This makes the link electrically conductive thereby joining the circuit elements to a corresponding spare element on the semiconductor. The method permits for high density packing of circuit elements and creates a link without producing bulk material movement.
    Type: Grant
    Filed: March 23, 1987
    Date of Patent: May 30, 1989
    Assignee: INMOS Corporation
    Inventors: Robert E. Jones, Jr., Lee Kammerdiner, Michael R. Reeder
  • Patent number: 4414057
    Abstract: A process is described for anisotropically etching semiconductor products which include a lower dielectric layer, an intermediate polysilicon layer, and an upper silicide layer such as titanium silicide. A pattern-defining layer will normally overlie the silicide layer to define target areas to be etched. In a first step, the silicide is etched through using Freon 115 chloro, pentafluoroethane (C.sub.2 ClF.sub.5) in a plasma etching chamber conditioned to provide a reactive ion etch. The etch is completed in the same chamber using a second gas which includes an amount of Cl.sub.2 selected to etch anisotropically through the polysilicon layer without substantially etching the dielectric layer. Preferably, both etches occur after covering inner surfaces of the etching chamber with a material which releases molecules of the character included in the pattern-defining layer, such as Kapton, a polymide, in the disclosed example.
    Type: Grant
    Filed: December 3, 1982
    Date of Patent: November 8, 1983
    Assignee: Inmos Corporation
    Inventors: Ronald R. Bourassa, Michael R. Reeder