Patents by Inventor Michael R. Tracey
Michael R. Tracey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9139542Abstract: The invention relates to a crystalline form of a triethylamine salt of (2Z)-2-(2 -amino-5-chlorothiazol-4-yl)-2-(3-N-tert-butoxycarbonylaminopropoxyimino)acetic acid. The invention also relates to processes and intermediates for preparing the crystalline form. The crystalline form is useful as an intermediate for preparing cross-linked glycopeptide-cephalosporin antibiotics.Type: GrantFiled: March 6, 2014Date of Patent: September 22, 2015Assignee: THERAVANCE BIOPHARMA ANTIBIOTICS IP, LLCInventors: Weijiang Zhang, Michael R. Tracey, Junning Lee
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Publication number: 20140275554Abstract: The invention relates to a crystalline form of a triethylamine salt of (2Z)-2-(2-amino-5-chlorothiazol-4-yl)-2-(3-N-tert-butoxycarbonylaminopropoxyimino)acetic acid. The invention also relates to processes and intermediates for preparing the crystalline form. The crystalline form is useful as an intermediate for preparing cross-linked glycopeptide-cephalosporin antibiotics.Type: ApplicationFiled: March 6, 2014Publication date: September 18, 2014Applicant: THERAVANCE, INC.Inventors: Weijiang Zhang, Michael R. Tracey, Junning Lee
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Publication number: 20140249361Abstract: A system and method for stimulating a target such as a nerve, wherein the system includes a first waveform generator adapted to generate a first waveform having a frequency capable of stimulating a predetermined target of the mammal, a second waveform generator adapted to generate a carrier waveform having a frequency capable of passing through tissue of the mammal, a modulation device electrically coupled to the first and second waveform generators and adapted to modulate the first and carrier waveforms to create a modulated waveform, and an electrode electrically coupled to the modulation device and positioned substantially adjacent to skin of the mammal, and adapted to apply the modulated waveform thereto.Type: ApplicationFiled: May 8, 2014Publication date: September 4, 2014Applicant: Ethicon, Inc.Inventors: Anthony R. DiUbaldi, Michael R. Tracey
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Patent number: 8751003Abstract: A medial treatment device for treating at least first and second medical conditions is provided, as well as a method for using the same. The medical treatment device includes a stimulation device for treating the first medical condition with electrical stimulation, and an implantable mesh adapted for implantation within the patient to treat the second medical condition. The implantable mesh has a plurality of incorporated electrically conductive elements adapted to conduct electrical stimulation from the stimulation device to a position closer to a predetermined body part the stimulation of which at least partially treats the first medical condition.Type: GrantFiled: August 2, 2006Date of Patent: June 10, 2014Assignee: Ethicon, Inc.Inventors: Anthony DiUbaldi, Michael R. Tracey
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Patent number: 8588930Abstract: A method for stimulating a predetermined body part such as a nerve using a stimulation device including an external non-implantable transmitting device powered by a power source and generating an electrical waveform signal. A surface electrode applies the generated electrical waveform signal transcutaneously. An implantable piezoelectric element receives the applied electrical waveform signal generated transcutaneously and, in turn, causes mechanical deformation resulting in mechanical vibration of the implantable piezoelectric element sufficient to stimulate the predetermined body part. The electrical waveform signal may be either a high frequency continuous waveform or high frequency burst packets.Type: GrantFiled: March 26, 2010Date of Patent: November 19, 2013Assignee: Ethicon, Inc.Inventors: Anthony DiUbaldi, Stephen Wahlgren, Michael R. Tracey
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Patent number: 8583256Abstract: A system and method for stimulating a nerve, wherein the system includes a first waveform generator adapted to generate a first waveform having a frequency capable of stimulating a predetermined nerve of the mammal, a second waveform generator adapted to generate a carrier waveform having a frequency capable of passing through tissue of the mammal, a modulation device electrically coupled to the first and second waveform generators and adapted to modulate the first and carrier waveforms to create a modulated waveform, and an electrode electrically coupled to the modulation device and positioned substantially adjacent to skin of the mammal, and adapted to apply the modulated waveform thereto.Type: GrantFiled: April 26, 2011Date of Patent: November 12, 2013Assignee: Ethicon, Inc.Inventors: Michael R. Tracey, Anthony DiUbaldi
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Patent number: 8165695Abstract: A device and method is provided for transdermally stimulating selected body parts of a mammal. The device includes a first waveform generator adapted to generate a first waveform having a first frequency capable of stimulating a first predetermined body part, a second waveform generator adapted to generate a carrier waveform having a second frequency capable of passing through tissue of the mammal, and a third waveform generator adapted to generate a third waveform having a third frequency different from and out of phase with that of the first waveform, and capable of stimulating a second predetermined body part.Type: GrantFiled: January 31, 2006Date of Patent: April 24, 2012Assignee: Ethicon, Inc.Inventors: Anthony DiUbaldi, Michael R. Tracey
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Patent number: 8128576Abstract: An implantable urodynamic system includes an implantable first device deployable in a patient's bladder, an implantable second device deployable in a patient's vaginal canal, and a data acquisition and analysis module or processing unit external to the body of the patient. The first device includes a magnet and an inductive coil, and the second device includes a magnet, an inductive coil and a battery. When deployed in the patient's body, attraction between the magnets maintains the two devices in close proximity to one another to effect an inductive coupling between the coils so that the first device may be powered by the battery of the second device. The urodynamic system is intended to facilitate measurement, collection, and wireless transmission of real-time, or near real-time, data (bladder pressure, abdominal pressure, and temperature) from an ambulatory patient.Type: GrantFiled: December 7, 2006Date of Patent: March 6, 2012Assignee: Ethicon, Inc.Inventors: Michael R. Tracey, Anthony DiUbaldi, Stephen Wahlgren, Rex O. Bare, Bradley J. Sargent
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Publication number: 20110264163Abstract: A system and method for stimulating a nerve, wherein the system includes a first waveform generator adapted to generate a first waveform having a frequency capable of stimulating a predetermined nerve of the mammal, a second waveform generator adapted to generate a carrier waveform having a frequency capable of passing through tissue of the mammal, a modulation device electrically coupled to the first and second waveform generators and adapted to modulate the first and carrier waveforms to create a modulated waveform, and an electrode electrically coupled to the modulation device and positioned substantially adjacent to skin of the mammal, and adapted to apply the modulated waveform thereto.Type: ApplicationFiled: April 26, 2011Publication date: October 27, 2011Applicant: ETHICON, INC.Inventors: Michael R. Tracey, Anthony DiUbaldi
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Patent number: 7979137Abstract: A system and method for stimulating a nerve, wherein the system includes a first waveform generator adapted to generate a first waveform having a frequency capable of stimulating a predetermined nerve of the mammal, a second waveform generator adapted to generate a carrier waveform having a frequency capable of passing through tissue of the mammal, a modulation device electrically coupled to the first and second waveform generators and adapted to modulate the first and carrier waveforms to create a modulated waveform, and an electrode electrically coupled to the modulation device and positioned substantially adjacent to skin of the mammal, and adapted to apply the modulated waveform thereto.Type: GrantFiled: June 7, 2005Date of Patent: July 12, 2011Assignee: Ethicon, Inc.Inventors: Michael R. Tracey, Anthony DiUbaldi
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Patent number: 7970478Abstract: A method and system for optimizing stimulation therapy of an external stimulating device. The stimulating signal for stimulation of a target nerve is produced using the external stimulating device. A magnetic field is induced in an implanted transmitting coil disposed proximate the target nerve when the action potential is fired along an axon of the target nerve. In turn, a feedback signal is generated in a receiving coil associated with the external stimulating device based on whether the target nerve fires an action potential. Stimulating signal parameters of the stimulating signal are adjusted based on the feedback signal.Type: GrantFiled: December 19, 2008Date of Patent: June 28, 2011Assignee: Ethicon, Inc.Inventors: Stephen Wahlgren, Michael R. Tracey
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Patent number: 7942806Abstract: A suburethral implant for treating stress urinary incontinence (SUI) includes an elongated plate-like member which is slightly curved in transverse cross-section, and a pair of spaced apart arms having hooked ends or barbs which extend from the plate-like member. A device for deploying the suburethral implant for treating SUI includes a vaginal probe for insertion in the vaginal canal of a patient, and a urethra locator probe for the simultaneous insertion in the urethra of a patient. The urethra probe is spaced apart from and overlies the vaginal probe. The vaginal probe includes a wall in which is formed an exit port. A suburethral implant introducer assembly is extendable and retractable through the exit port on the vaginal probe. The introducer assembly has a distal end on which is removably mounted a suburethral implant.Type: GrantFiled: December 29, 2005Date of Patent: May 17, 2011Assignee: Ethicon, Inc.Inventors: Michael R. Tracey, Steve Bell, Bryan Knodel
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Publication number: 20100249677Abstract: A method for stimulating a predetermined body part such as a nerve using a stimulation device including an external non-implantable transmitting device powered by a power source and generating an electrical waveform signal. A surface electrode applies the generated electrical waveform signal transcutaneously. An implantable piezoelectric element receives the applied electrical waveform signal generated transcutaneously and, in turn, causes mechanical deformation resulting in mechanical vibration of the implantable piezoelectric element sufficient to stimulate the predetermined body part. The electrical waveform signal may be either a high frequency continuous waveform or high frequency burst packets.Type: ApplicationFiled: March 26, 2010Publication date: September 30, 2010Applicant: Ethicon, Inc.Inventors: Anthony DiUbaldi, Stephen Wahlgren, Michael R. Tracey
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Publication number: 20100161005Abstract: A method and system for optimizing stimulation therapy of an external stimulating device. The stimulating signal for stimulation of a target nerve is produced using the external stimulating device. A magnetic field is induced in an implanted transmitting coil disposed proximate the target nerve when the action potential is fired along an axon of the target nerve. In turn, a feedback signal is generated in a receiving coil associated with the external stimulating device based on whether the target nerve fires an action potential. Stimulating signal parameters of the stimulating signal are adjusted based on the feedback signal.Type: ApplicationFiled: December 19, 2008Publication date: June 24, 2010Applicant: Ethicon, Inc.Inventors: Stephen Wahlgren, Michael R. Tracey
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Patent number: 7647112Abstract: Devices and methods are provided for electrically stimulating a predetermined body part of a mammal. The method includes placing at least one electrode in proximity to the mammal's skin, injecting an electrically conductive gel into the body of the mammal so as to form a conductive gel pathway extending at least partially along a distance between the at least one electrode and the predetermined body part, and stimulating the predetermined body part by applying an electrical signal via the electrode that travels, at least in part, through the conductive gel pathway.Type: GrantFiled: January 31, 2006Date of Patent: January 12, 2010Assignee: Ethicon, Inc.Inventors: Michael R. Tracey, Anthony DiUbaldi, Douglas B. Johns
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Publication number: 20090149918Abstract: An antenna implantable through minimally invasive techniques, preferably comprising a coil with conductive probes is provided. The antenna is preferably superelastic nickel-titanium having an insulative coating. The antenna may conduct a signal originating from a device external to the body of the implantee, or from another implanted device connected to the antenna depending on whether the antenna is employed for sending, receiving, or transceiving signals. Signals may contain data, operational commands, and may be used to transfer power. The implantable antenna may be connected to another implanted device, such as a blood pressure monitor, or may be implanted as a stand-alone device for purposes such as stimulating tissue.Type: ApplicationFiled: December 6, 2007Publication date: June 11, 2009Inventors: Peter Krulevitch, Michael R. Tracey, Stuart Wenzel
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Publication number: 20080139875Abstract: An implantable urodynamic system includes an implantable first device deployable in a patient's bladder, an implantable second device deployable in a patient's vaginal canal, and a data acquisition and analysis module or processing unit external to the body of the patient. The first device includes a magnet and an inductive coil, and the second device includes a magnet, an inductive coil and a battery. When deployed in the patient's body, attraction between the magnets maintains the two devices in close proximity to one another to effect an inductive coupling between the coils so that the first device may be powered by the battery of the second device. The urodynamic system is intended to facilitate measurement, collection, and wireless transmission of real-time, or near real-time, data (bladder pressure, abdominal pressure, and temperature) from an ambulatory patient.Type: ApplicationFiled: December 7, 2006Publication date: June 12, 2008Inventors: Michael R. Tracey, Anthony DiUbaldi, Stephen Wahlgren, Rex O. Bare, Bradley J. Sargent
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Publication number: 20080132962Abstract: A device for transcutaneous electrical stimulation device for affecting gastric function in a patient and a method for performing the same is provided. The device includes a first waveform generator adapted to generate a first waveform having a first frequency capable of stimulating a vagus nerve of the patient at a predetermined location, a second waveform generator adapted to generate a carrier waveform having a second frequency capable of passing from the surface of skin of the patient at the predetermined location, through tissue to the vagus nerve, a modulation device electrically coupled to the first, second and third waveform generators and adapted to modulate the first and carrier waveforms to create a modulated signal, and a first electrode electrically coupled to the modulation device and positioned substantially adjacent to the skin of the mammal, and adapted to apply the modulated signal thereto.Type: ApplicationFiled: December 1, 2006Publication date: June 5, 2008Inventors: Anthony DiUbaldi, Michael R. Tracey, Stephen B. Wahlgren
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Patent number: 7255673Abstract: A method is provided for assessing urinary function including removably coupling a first test module to a portable control device, selecting from a plurality of different tests a first test to assess urinary function, the selection being made based on first module identification information obtained by the control device from the test module, and performing the first test. The method may also include one or more of the steps of inserting an insert member coupled to the first test module at least partially into a patient's urinary tract, infusing fluid through the insert member into the urinary tract, and measuring pressure within the urinary tract as fluid is infused therein.Type: GrantFiled: June 27, 2002Date of Patent: August 14, 2007Assignee: Ethicon, Inc.Inventors: Ulf Ulmsten, Michael R. Tracey, Martin Nohilly
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Patent number: 7252631Abstract: A method is provided for diagnosing detrusor instability. The method includes using an insert member having a channel therethrough positioned distal of the urethral sphincter, creating a substantially fluid tight seal to substantially block fluid flow into or out of the urethral canal other than through the channel, infusing fluid from a fluid source through the channel in the insert member and into the urethral canal at a location distal of the urethral sphincter, and measuring a pressure within the urethral canal at a location distal of the urethral sphincter as the fluid is being infused therein. The infusing step further involves infusing fluid until the urethral sphincter opens, and thereafter until at least one detrusor contraction occurs.Type: GrantFiled: September 30, 2003Date of Patent: August 7, 2007Assignee: Ethicon, Inc.Inventor: Michael R. Tracey