Patents by Inventor Michael Ragusa
Michael Ragusa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20160334307Abstract: A flow through fluid sampling system includes a sample tube and a cap. The sample tube is configured to collect a sample of a fluid and has an open top. The cap is configured to be secured to the sample tube to close the open top. The cap includes an inflow port configured to allow fluid to enter the fluid sample tube, an outflow port configured to allow fluid to leave the sample tube.Type: ApplicationFiled: January 12, 2015Publication date: November 17, 2016Applicant: Haemonetics CorporationInventors: Michael Ragusa, Matthew Murphy
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Patent number: 9370615Abstract: An apparatus for separating whole blood includes an access device for drawing whole blood from a source, a blood component separation device, a draw line, a draw pump, and a controller. The blood component separation device separates the drawn whole blood into a first blood component and a second blood component. The draw line fluidly connects the access device and the blood component separation device, and the draw pump draws whole blood from the source through the access device and draw line and into the blood component separation device. The controller controls fluid flow through the apparatus and operation of the draw pump. The controller also monitors the total volume of whole blood drawn from the source and the total volume of first blood component collected. The controller stops the draw pump when the first of a target whole blood volume is withdrawn or a target volume of first blood component is collected.Type: GrantFiled: October 4, 2013Date of Patent: June 21, 2016Assignee: Haemonetics CorporationInventors: Michael Ragusa, Shiven Ruparel, Dominique Uhlmann
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Patent number: 9364600Abstract: A blood processing device includes a venous-access device, a blood component separation device, a return line, a draw line, a first pressure sensor, a second pressure sensor, and a first pump. The first pressure sensor is located on the return line between the blood component separation device and the venous-access device, and determines a first pressure. The second pressure sensor is located on the draw line between the blood component separation device and the venous-access device, and determines a second pressure. The first pump is connected to at least one of the return line and the draw line and controls a flow rate within the connected line based on a subject access pressure determined based upon the first and second pressures.Type: GrantFiled: January 29, 2014Date of Patent: June 14, 2016Assignee: Haemonetics CorporationInventors: Etienne Pagès, Michael Ragusa
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Publication number: 20160106908Abstract: A method for the re-anticoagulation of platelet rich plasma in a blood apheresis system includes priming the blood apheresis system with anticoagulant, such that a volume of anticoagulant is transferred to a PRP container. The method may then transfer the anticoagulant within the PRP container to a red blood cell container, and collect a volume of platelet rich plasma within the PRP container. The platelet rich plasma may be collected in a plurality of cycles. Between collection cycles, the method may transfer a portion of the volume of anticoagulant from the red blood cell container to the PRP container.Type: ApplicationFiled: December 21, 2015Publication date: April 21, 2016Inventors: Etienne Pagès, Michael Ragusa
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Patent number: 9248227Abstract: A method for the re-anticoagulation of platelet rich plasma in a blood apheresis system includes priming the blood apheresis system with anticoagulant, such that a volume of anticoagulant is transferred to a PRP container. The method may then transfer the anticoagulant within the PRP container to a red blood cell container, and collect a volume of platelet rich plasma within the PRP container. The platelet rich plasma may be collected in a plurality of cycles. Between collection cycles, the method may transfer a portion of the volume of anticoagulant from the red blood cell container to the PRP container.Type: GrantFiled: August 14, 2014Date of Patent: February 2, 2016Assignee: Haemonetics CorporationInventors: Etienne Pagès, Michael Ragusa
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Publication number: 20150273132Abstract: An apparatus for separating whole blood includes a continuous flow separation device in which drawn whole blood is separated into a first and second blood component. The separation device has an inlet for introducing whole blood into the separation device, a first blood component outlet for withdrawing the first blood component, and a second blood component outlet for withdrawing the second blood component. The apparatus also includes a first blood component storage container connected to the first blood component outlet, and a first blood component pump to draw the first blood component from the separation device. Additionally, the apparatus can have second blood component storage container connected to the second blood component outlet, and a controller for controlling fluid flow through the apparatus. The controller monitors the total volume of whole blood drawn from the source, and stops a draw pump when the target whole blood volume is withdrawn.Type: ApplicationFiled: November 5, 2012Publication date: October 1, 2015Inventors: Michael Ragusa, Shiven Ruparel, Dominique Uhlmann
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Patent number: 9095665Abstract: A blood processing system for collecting and exchanging blood components includes a venous-access device for drawing whole blood from a subject and returning blood components to the subject. The system may include three lines connecting the venous access device to a blood component separation device and an anticoagulant source. A blood draw line fluidly connects to the venous-access device to the blood component separation device. An anticoagulant line introduces anticoagulant into the drawn whole blood. A return line, fluidly connected to the venous-access device and the blood component separation device, returns uncollected blood component to the subject. Each line may have a pump that controls flow through the line. The blood component separation device separates the drawn blood into a first blood component and a second blood component, and may be configured to send the first blood component to a first blood component bag.Type: GrantFiled: December 10, 2013Date of Patent: August 4, 2015Assignee: Haemonetics CorporationInventors: Etienne Pagès, Michael Ragusa
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Publication number: 20140356851Abstract: A method for the re-anticoagulation of platelet rich plasma in a blood apheresis system includes priming the blood apheresis system with anticoagulant, such that a volume of anticoagulant is transferred to a PRP container. The method may then transfer the anticoagulant within the PRP container to a red blood cell container, and collect a volume of platelet rich plasma within the PRP container. The platelet rich plasma may be collected in a plurality of cycles. Between collection cycles, the method may transfer a portion of the volume of anticoagulant from the red blood cell container to the PRP container.Type: ApplicationFiled: August 14, 2014Publication date: December 4, 2014Inventors: Etienne Pagès, Michael Ragusa
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Patent number: 8834402Abstract: A method for the re-anticoagulation of platelet rich plasma in a blood apheresis system includes priming the blood apheresis system with anticoagulant, such that a volume of anticoagulant is transferred to a PRP container. The method may then transfer the anticoagulant within the PRP container to a red blood cell container, and collect a volume of platelet rich plasma within the PRP container. The platelet rich plasma may be collected in a plurality of cycles. Between collection cycles, the method may transfer a portion of the volume of anticoagulant from the red blood cell container to the PRP container.Type: GrantFiled: March 12, 2009Date of Patent: September 16, 2014Assignee: Haemonetics CorporationInventors: Etienne Pagès, Michael Ragusa
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Patent number: 8808217Abstract: A method and apparatus for collecting plasma reduced platelets potentially suspended in a synthetic solution from a donor. Whole blood is drawn from the donor and introduced into a separation chamber. Platelets are extracted from the separation chamber into a container, using, for example, surge (with anticoagulated plasma or a synthetic solution) or push methodologies. The remaining blood components in the separation chamber are returned back to the donor. The steps of drawing whole blood and introducing the whole blood into the separation chamber, extracting platelets from the separation chamber into the container, and returning the remaining components in the chamber back to the donor are repeated. The sequestered platelets in the container are reintroduced into the separation chamber, whereupon a plasma reduced platelet product is extracted.Type: GrantFiled: May 2, 2013Date of Patent: August 19, 2014Assignee: Haemonetics CorporationInventors: Toshiyasu Ohashi, Etienne Pagès, Dominique Uhlmann, Pascal Maillard, Michael Ragusa
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Publication number: 20140148750Abstract: A blood processing device includes a venous-access device, a blood component separation device, a return line, a draw line, a first pressure sensor, a second pressure sensor, and a first pump. The first pressure sensor is located on the return line between the blood component separation device and the venous-access device, and determines a first pressure. The second pressure sensor is located on the draw line between the blood component separation device and the venous-access device, and determines a second pressure. The first pump is connected to at least one of the return line and the draw line and controls a flow rate within the connected line based on a subject access pressure determined based upon the first and second pressures.Type: ApplicationFiled: January 29, 2014Publication date: May 29, 2014Applicant: Haemonetics CorporationInventors: Etienne Pagès, Michael Ragusa
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Publication number: 20140128239Abstract: A continuous flow centrifuge bowl includes a rotatable outer body, and a top and bottom core that are rotatable with the outer body. The bottom core has a wall extending proximally from a bottom wall. The proximally extending wall is radially outward from at least a portion of the top core and, together with the top core, defines a primary separation region in which initial separation of the whole blood occurs. The bowl may also have a secondary separation region located between the top core and the outer body, and a rotary seal that couples an inlet port and two outlet ports to the outer body. The inlet port may be connected to an inlet tube that extends distally into a whole blood introduction region. Additionally, one of the outlet ports may be connected to an extraction tube that extends into a region below the bottom core.Type: ApplicationFiled: November 5, 2013Publication date: May 8, 2014Applicant: Haemonetics CorporationInventors: Matthew Murphy, Dominique Uhlmann, Edward Powers, Michael Ragusa, Etienne Pagès
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Patent number: 8702637Abstract: A blood processing device includes a venous-access device, a blood component separation device, a return line, a draw line, a first pressure sensor, a second pressure sensor, and a first pump. The first pressure sensor is located on the return line between the blood component separation device and the venous-access device, and determines a first pressure. The second pressure sensor is located on the draw line between the blood component separation device and the venous-access device, and determines a second pressure. The first pump is connected to at least one of the return line and the draw line and controls a flow rate within the connected line based on a subject access pressure determined based upon the first and second pressures.Type: GrantFiled: April 14, 2008Date of Patent: April 22, 2014Assignee: Haemonetics CorporationInventors: Etienne Pagès, Michael Ragusa
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Publication number: 20140100506Abstract: A blood processing system for collecting and exchanging blood components includes a venous-access device for drawing whole blood from a subject and returning blood components to the subject. The system may include three lines connecting the venous access device to a blood component separation device and an anticoagulant source. A blood draw line fluidly connects to the venous-access device to the blood component separation device. An anticoagulant line introduces anticoagulant into the drawn whole blood. A return line, fluidly connected to the venous-access device and the blood component separation device, returns uncollected blood component to the subject. Each line may have a pump that controls flow through the line. The blood component separation device separates the drawn blood into a first blood component and a second blood component, and may be configured to send the first blood component to a first blood component bag.Type: ApplicationFiled: December 10, 2013Publication date: April 10, 2014Applicant: Haemonetics CorporationInventors: Etienne Pagès, Michael Ragusa
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Patent number: 8647289Abstract: A blood processing device includes a venous-access device, a blood component separation device, a return line, a draw line, a first pressure sensor, a second pressure sensor, and a first pump. The first pressure sensor is located on the return line between the blood component separation device and the venous-access device, and determines a first pressure. The second pressure sensor is located on the draw line between the blood component separation device and the venous-access device, and determines a second pressure. The first pump is connected to at least one of the return line and the draw line and controls a flow rate within the connected line based on a subject access pressure determined based upon the first and second pressures.Type: GrantFiled: March 31, 2011Date of Patent: February 11, 2014Assignee: Haemonetics CorporationInventors: Etienne Pagès, Michael Ragusa
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Publication number: 20140039373Abstract: An apparatus for separating whole blood includes an access device for drawing whole blood from a source, a blood component separation device, a draw line, a draw pump, and a controller. The blood component separation device separates the drawn whole blood into a first blood component and a second blood component. The draw line fluidly connects the access device and the blood component separation device, and the draw pump draws whole blood from the source through the access device and draw line and into the blood component separation device. The controller controls fluid flow through the apparatus and operation of the draw pump. The controller also monitors the total volume of whole blood drawn from the source and the total volume of first blood component collected. The controller stops the draw pump when the first of a target whole blood volume is withdrawn or a target volume of first blood component is collected.Type: ApplicationFiled: October 4, 2013Publication date: February 6, 2014Applicant: Haemonetics CorporationInventors: Michael Ragusa, Shiven Ruparel, Dominique Uhlmann
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Patent number: 8628489Abstract: A blood processing system for collecting and exchanging blood components includes a venous-access device for drawing whole blood from a subject and returning blood components to the subject. The system may also include three lines connecting the venous access device to a blood component separation device and an anticoagulant source. A blood draw line fluidly connects to the venous-access device to the blood component separation device. An anticoagulant line introduces anticoagulant into the drawn whole blood. A return line, fluidly connected to the venous-access device and the blood component separation device, and returns uncollected blood component to the subject. Each line may have a pump that controls flow through the line. The blood component separation device separates the drawn blood into a first blood component and a second blood component, and may be configured to send the first blood component to a first blood component bag.Type: GrantFiled: April 14, 2008Date of Patent: January 14, 2014Assignee: Haemonetics CorporationInventors: Etienne Pagès, Michael Ragusa
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Patent number: 8591448Abstract: A fluid cassette for a blood processing system includes a cassette housing and a rigid structure. The cassette housing defines the structure of the cassette and has a fluid path at least partially extending through it. The fluid path is configured to allow a fluid to pass through the housing. The rigid structure defines a cavity that is in fluid communication with the fluid path. The rigid structure also has an interface for interfacing and/or connecting with a pressure monitoring device. The interface allows the pressure monitoring device to measure the pressure within the fluid path. The cavity has a volume of air located between the fluid path and the interface.Type: GrantFiled: May 13, 2009Date of Patent: November 26, 2013Assignee: Haemonetics CorporationInventors: Edward T. Powers, Matthew J. Murphy, Michael Ragusa
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Publication number: 20130240422Abstract: A method and apparatus for collecting plasma reduced platelets potentially suspended in a synthetic solution from a donor. Whole blood is drawn from the donor and introduced into a separation chamber. Platelets are extracted from the separation chamber into a container, using, for example, surge (with anticoagulated plasma or a synthetic solution) or push methodologies. The remaining blood components in the separation chamber are returned back to the donor. The steps of drawing whole blood and introducing the whole blood into the separation chamber, extracting platelets from the separation chamber into the container, and returning the remaining components in the chamber back to the donor are repeated. The sequestered platelets in the container are reintroduced into the separation chamber, whereupon a plasma reduced platelet product is extracted.Type: ApplicationFiled: May 2, 2013Publication date: September 19, 2013Applicant: Haemonetics CorporationInventors: Toshiyasu Ohashi, Etienne Pagès, Dominique Uhlmann, Pascal Maillard, Michael Ragusa
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Patent number: 8454548Abstract: A method and apparatus for collecting plasma reduced platelets potentially suspended in a synthetic solution from a donor. Whole blood is drawn from the donor and introduced into a separation chamber. Platelets are extracted from the separation chamber into a container, using, for example, surge (with anticoagulated plasma or a synthetic solution) or push methodologies. The remaining blood components in the separation chamber are returned back to the donor. The steps of drawing whole blood and introducing the whole blood into the separation chamber, extracting platelets from the separation chamber into the container, and returning the remaining components in the chamber back to the donor are repeated. The sequestered platelets in the container are reintroduced into the separation chamber, whereupon a plasma reduced platelet product is extracted.Type: GrantFiled: April 14, 2008Date of Patent: June 4, 2013Assignee: Haemonetics CorporationInventors: Toshiyasu Ohashi, Etienne Pagès, Dominique Uhlmann, Pascal Maillard, Michael Ragusa