Abstract: The present disclosure relates to systems and methods for assessing severity of involuntary movement associated with tardive dyskinesia (TD). The method includes receiving video data of the patient. The video data may include facial movements of the patient. The method includes processing the video data to identify facial landmark data of the patient, which may include applying an image processing technique to the video data to identify facial landmarks on one or more frames of the video data to produce labeled frames. The method may include applying a plurality of trained machine learning models to the facial landmark data to determine one or more movement severity scores based on changes in the facial landmark data of the patient, where each movement severity score is representative of a category of facial movement, and a total severity score may be generated based on multiple movement severity scores.

Abstract: A structural element for a motor vehicle chassis, particularly a chassis of an electrically powered motor vehicle, includes at least two securing sections and a central section which connects the two securing sections. Each securing section can be secured to an outer surface of a motor mounting element of the chassis and/or to an outer surface of a longitudinal member of the chassis.

Abstract: Provided is a system for determining a probability of a respiratory disease exacerbation in a subject. The system comprises an inhaler arrangement for delivering a medicament to the subject. The medicament may be a rescue medicament and/or a maintenance medicament. The inhaler arrangement has a use-detection system configured to determine an inhalation performed by the subject using the inhaler arrangement. A sensor system is configured to measure a parameter relating to airflow during the inhalation. A user interface enables user-input of an indication of a status of the respiratory disease being experienced by the subject. A processor is configured to determine the probability of the respiratory disease exacerbation based on the recorded inhalation(s) from the use-detection system, the parameter(s) received from the sensor system, and the indication received from the user interface. Further provided is a method for determining the probability of a respiratory disease exacerbation in a subject.

Abstract: Provided is a system for determining a probability of a respiratory disease exacerbation in a subject. The system comprises an inhaler arrangement for delivering a medicament to the subject. The medicament may be a rescue medicament and/or a maintenance medicament. The inhaler arrangement has a use-detection system configured to determine an inhalation performed by the subject using the inhaler arrangement. A sensor system is configured to measure a parameter relating to airflow during the inhalation. A user interface enables user-input of an indication of a status of the respiratory disease being experienced by the subject. A processor is configured to determine the probability of the respiratory disease exacerbation based on the recorded inhalation(s) from the use-detection system, the parameter(s) received from the sensor system, and the indication received from the user interface. Further provided is a method for determining the probability of a respiratory disease exacerbation in a subject.

Abstract: Provided is a system (10) for determining a probability of an asthma exacerbation in a subject. The system comprises an inhaler (100) for delivering a rescue medicament to the subject. The inhaler has a use-detection system (12B) configured to determine a rescue inhalation performed by the subject using the first inhaler. A sensor system (12A) is configured to measure a parameter relating to airflow during the rescue inhalation. The system further comprises a processor (14) configured to determine a number of the rescue inhalations during a first time period, and receive the parameter measured for at least some of the rescue inhalations. The processor determines, using a weighted model, the probability of the asthma exacerbation based on the number of rescue inhalations and the parameters. The model is weighted such that the number of rescue inhalations is more significant in the probability determination than the parameters.

Abstract: A cargo handling system includes a wireless cargo emergency stop system, a power relay communicatively coupled to the wireless cargo emergency stop system, and a power drive unit communicatively coupled to the power relay and the wireless cargo emergency stop system. Power to the power drive unit is removed in response to an emergency stop activated via the wireless cargo emergency stop system.

Abstract: Provided is a system (10) for determining a probability of an asthma exacerbation in a subject. The system comprises an inhaler (100) for delivering a rescue medicament to the subject. The inhaler has a use-detection system (12B) configured to determine a rescue inhalation performed by the subject using the first inhaler. A sensor system (12A) is configured to measure a parameter relating to airflow during the rescue inhalation. The system further comprises a processor (14) configured to determine a number of the rescue inhalations during a first time period, and receive the parameter measured for at least some of the rescue inhalations. The processor determines, using a weighted model, the probability of the asthma exacerbation based on the number of rescue inhalations and the parameters. The model is weighted such that the number of rescue inhalations is more significant in the probability determination than the parameters.

Abstract: Provided is a method for generating an assessment of a respiratory disease in a subject at a current point in time. The method comprises determining a baseline statistic relating to usage of an inhaler in a baseline period. The inhaler is configured to deliver a rescue medicament to the subject, and has a use determination system configured to determine usage of the inhaler by the subject. The method also comprises determining a current statistic relating to usage of the inhaler in a current period containing the current point in time. The method further comprises generating a comparator variable. Generating the comparator variable comprises comparing the current statistic and the baseline statistic. The assessment of the respiratory disease is based on the comparator variable.

Abstract: A structural element for a motor vehicle chassis, particularly a chassis of an electrically powered motor vehicle, includes at least two securing sections and a central section which connects the two securing sections. Each securing section can be secured to an outer surface of a motor mounting element of the chassis and/or to an outer surface of a longitudinal member of the chassis.

Abstract: Provided is a system for providing an output for warning of a respiratory disease exacerbation in a subject. The system comprises a first inhaler for delivering a rescue medicament to the subject. The system optionally includes a second inhaler for delivering a maintenance medicament to the subject during a routine inhalation. A sensor system is configured to measure a parameter relating to airflow during the rescue inhalation and/or during the routine inhalation, when the second inhaler is included in the system. The system further comprises a processing module configured to monitor a frequency of the determined rescue inhalations. The processing module also monitors the parameter as a function of time.

Abstract: Provided is a system comprising at least one inhaler. Each of the at least one inhaler comprises a use determination system configured to determine at least one value of a usage parameter relating to use of the respective inhaler by a subject. The system further comprises a user interface and a processing module. The user interface is configured to enable user-inputting of an indication of a status of a respiratory disease being experienced by the subject. The processing module is configured to control the user interface to issue a prompt to input the indication based on the at least one value.

Abstract: Provided is a system (10) for determining a probability of an asthma exacerbation in a subject. The system comprises an inhaler (100) for delivering a rescue medicament to the subject. The inhaler has a use-detection system (12B) configured to determine a rescue inhalation performed by the subject using the first inhaler. A sensor system (12A) is configured to measure a parameter relating to airflow during the rescue inhalation. The system further comprises a processor (14) configured to determine a number of the rescue inhalations during a first time period, and receive the parameter measured for at least some of the rescue inhalations. The processor determines, using a weighted model, the probability of the asthma exacerbation based on the number of rescue inhalations and the parameters. The model is weighted such that the number of rescue inhalations is more significant in the probability determination than the parameters.

Abstract: Provided is a system (10) for determining a probability of an asthma exacerbation in a subject. The system comprises an inhaler (100) for delivering a rescue medicament to the subject. The inhaler has a use-detection system (12B) configured to determine a rescue inhalation performed by the subject using the first inhaler. A sensor system (12A) is configured to measure a parameter relating to airflow during the rescue inhalation. The system further comprises a processor (14) configured to determine a number of the rescue inhalations during a first time period, and receive the parameter measured for at least some of the rescue inhalations. The processor determines, using a weighted model, the probability of the asthma exacerbation based on the number of rescue inhalations and the parameters. The model is weighted such that the number of rescue inhalations is more significant in the probability determination than the parameters.

Abstract: Provided is a system (10) for determining a probability of a CORD exacerbation in a subject. The system comprises a first inhaler (100) for delivering a rescue medicament to the subject. The rescue medicament may be suitable for treating the subject's acute respiratory disease, for example by effecting rapid dilation of the bronchi and bronchioles upon inhalation of the medicament. The first inhaler has a use-detection system (12B) configured to determine a rescue inhalation performed by the subject using the first inhaler. The system optionally includes a second inhaler for delivering a maintenance medicament to the subject during a routine inhalation A sensor system (12A) is configured to measure a parameter relating to airflow during the rescue inhalation and/or during the routine inhalation, when the second inhaler is included in the system.

Abstract: Provided is a system for determining a probability of a respiratory disease exacerbation in a subject. The system comprises an inhaler arrangement for delivering a medicament to the subject. The medicament may be a rescue medicament and/or a maintenance medicament. The inhaler arrangement has a use-detection system configured to determine an inhalation performed by the subject using the inhaler arrangement. A sensor system is configured to measure a parameter relating to airflow during the inhalation. A user interface enables user-input of an indication of a status of the respiratory disease being experienced by the subject. A processor is configured to determine the probability of the respiratory disease exacerbation based on the recorded inhalation(s) from the use-detection system, the parameter(s) received from the sensor system, and the indication received from the user interface. Further provided is a method for determining the probability of a respiratory disease exacerbation in a subject.

Abstract: Provided is a system (10) for determining a probability of an asthma exacerbation in a subject. The system comprises an inhaler (100) for delivering a rescue medicament to the subject. The inhaler has a use-detection system (12B) configured to determine a rescue inhalation performed by the subject using the first inhaler. A sensor system (12A) is configured to measure a parameter relating to airflow during the rescue inhalation. The system further comprises a processor (14) configured to determine a number of the rescue inhalations during a first time period, and receive the parameter measured for at least some of the rescue inhalations. The processor determines, using a weighted model, the probability of the asthma exacerbation based on the number of rescue inhalations and the parameters. The model is weighted such that the number of rescue inhalations is more significant in the probability determination than the parameters.

Abstract: The invention relates to a brake, comprising at least one brake actuating element, which is operatively connected to a planetary-roller threaded unit and to an electrical drive in order to move the brake actuating element between a braking position and an axially offset non-braking position of the brake actuating element, wherein the planetary-roller threaded unit has a plurality of threaded roller elements distributed in the circumferential direction, the threaded roller elements being in threaded engagement with a spindle element connected in a rotationally fixed manner to the electrical drive and with a stationary housing, and wherein the threaded roller elements are rotatably arranged about the axes thereof, which are each arranged parallel to an axis of the spindle element, and about the axis of the spindle element, wherein the brake actuating element is coupled only to the spindle element.

Abstract: An optoelectronic semiconductor device at least one radiation-emitting semiconductor chip (3); at least one converter element (4) disposed downstream of the semiconductor chip (3) and serving for converting electromagnetic radiation emitted by the semiconductor chip (3) during operation, wherein the converter element (4) emits colored light upon irradiation with ambient light; a means for diffusely scattering light (5), which is designed to scatter ambient light impinging on the device in a switched-off operating state of the device in such a way that a light exit area (62) of the device appears white.

Abstract: An imaging device for projecting an image onto a projection area includes a radiation-emitting component which emits electromagnetic radiation along an emission direction during operation, an image-generating element in the beam path of the radiation-emitting component, a radiation-directing element in the beam path of the radiation-emitting component for directing the electromagnetic radiation onto the projection area, and a radiation exit area, wherein the projection area is offset laterally with respect to the radiation exit area.

Abstract: A display device includes a light source, an optical waveguide element with an emission area, optical waveguide element configured to conduct light from the light source onto an emission area, and a transflective element arranged on the emission area including a first layer with at least one first subregion and at least one second subregion, the first layer configured to transmit light from emission area in the first subregion and not to transmit in the second subregion, and a second layer arranged above the first layer in the emission direction of the light, the second layer configured to transmit at least a part of the light from light source.