Abstract: The disclosure relates to block copolymer nanoparticles for in vivo therapeutic delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticles, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, for delivering nucleotides that encode polypeptides.

Abstract: The invention relates to a rotating mechanical seal arrangement (1) for sealing a product side (5) at a rotating component, comprising a first rotating mechanical seal (2) with a first rotating slide ring (21) and a first stationary slide ring (22) which define a first sealing gap (23) between them, a second rotating mechanical seal (3) with a second rotating slide ring (31) and a second stationary slide ring (32) which define a second sealing gap (33) between them, a fluid space (4) which is limited by the first and second rotating mechanical seals (2, 3), wherein the first rotating mechanical seal (2) is lubricated with a product medium of the product side (5), and wherein the second rotating mechanical seal (3) is lubricated with a liquid quench medium of a quench supply unit (7), the quench medium being located in the fluid space (4), a quench outlet (8) via which quench medium may be discharged from the fluid space (4), a gas outlet (9) via which a gas located in the fluid space may be discharged, and a

Abstract: The invention relates to a rotating mechanical seal arrangement (1) for sealing a product side (5) at a rotating component, comprising a first rotating mechanical seal (2) with a first rotating slide ring (21) and a first stationary slide ring (22) which define a first sealing gap (23) between them, a second rotating mechanical seal (3) with a second rotating slide ring (31) and a second stationary slide ring (32) which define a second sealing gap (33) between them, a fluid space (4) which is limited by the first and second rotating mechanical seals (2, 3), wherein the first rotating mechanical seal (2) is lubricated with a product medium of the product side (5), and wherein the second rotating mechanical seal (3) is lubricated with a liquid quench medium of a quench supply unit (7), the quench medium being located in the fluid space (4), a quench outlet (8) via which quench medium may be discharged from the fluid space (4), a gas outlet (9) via which a gas located in the fluid space may be discharged, and a

Abstract: Improved workpiece-carrier in the form of a high-temperature-grating 10 assembled from mutually engaging elements consisting of carbon-fiber-reinforced carbon-composite-board-strips comprising comb-shaped elements, having a frame surrounding a horizontal grating as well as at least one workpiece-support (40) which is inert in relation to the supported workpiece and provides a workpiece-support-area (50) at a distance above the grating (3O)7 said work-piece-support (40) being arranged within at least one enclosing cut-out-section of at least one element wherein furthermore said elements comprise at least one element having interlocking cut-out-sections in alternating arrangement, at least one auxiliary element, said workpiece-support (40) is a single-piece part of high temperature ceramic of rod-shaped elongation being arranged parallel to the plane of said grating (30) and being an integral part of the grating by being enclosed beneath the workpiece-support-area (50) by cut-out-sections of a multitude of cros

Abstract: The present invention refers to a seal ring comprising: a base region (20), a diamond coating (21) applied to the base region (20), and a lubricant coating (22) applied to the diamond coating (21), which adheres to the diamond coating and fills recesses (23) of the diamond coating (21). Furthermore, the present invention refers to a mechanical seal comprising at least one seal ring according to the invention.

Abstract: This invention relates to magnetic particles having a glass surface which are substantially spherical. This invention also relates to methods for making them, as well as to suspensions thereof and their uses for the purification of DNA or RNA in particular in automated processes.

Abstract: Improved workpiece-carrier in the form of a high-temperature-grating 10 assembled from mutually engaging elements consisting of carbon-fibre-reinforced carbon-composite-board-strips comprising comb-shaped elements, having a frame surrounding a horizontal grating as well as at least one workpiece-support (40) which is inert in relation to the supported workpiece and provides a workpiece-support-area (50) at a distance above the grating (3O)7 said work-piece-support (40) being arranged within at least one enclosing cut-out-section of at least one element wherein furthermore said elements comprise at least one element having interlocking cut-out-sections in alternating arrangement, at least one auxiliary element, said workpiece-support (40) is a single-piece part of high temperature ceramic of rod-shaped elongation being arranged parallel to the plane of said grating (30) and being an integral part of the grating by being enclosed beneath the workpiece-support-area (50) by cut-out-sections of a multitude of cros

Abstract: This invention relates to magnetic particles having a glass surface which are substantially spherical. This invention also relates to methods for making them, as well as to suspensions thereof and their uses for the purification of DNA or RNA in particular in automated processes.

Abstract: Magnetic particles with an outer glass surface being essentially poreless or having pores of a diameter of less then 10 nm as well as ferromagnetic particles with a glass surface are preferentially useful for the isolation of biological material from samples. They provide a quick and reliable purification.

Abstract: Magnetic particles with an outer glass surface being essentially poreless or having pores of a diameter of less then 10 nm as well as ferromagnetic particles with a glass surface are preferentially useful for the isolation of biological material from samples. They provide a quick and reliable purification.

Abstract: A divided driver device (5) for a mechanical face seal for non-rotatable assembly on a rotary component and for the transmission of a torque to a seal ring (2) held in non-rotatable manner on the driver device. The driver device (5) is divided in at least a single radial plane so as to form sections in the form of segments of a circle that are adapted to be clamped together to form a ring shape and furthermore, it is axially sub-divided into a divided retaining ring (14) for retaining the seal ring (2) and a divided mounting ring (16) for non-rotatable mounting to the rotary component. The rings (14, 16) are coupled together for rotation in common, as indicted by (24).

Abstract: Magnetic particles are prepared containing a magnetic core coated with a glass layer having a substantially pore-free glass surface or having pores with a diameter of less than 10 nm. The particles are used for separating biological material such as nucleic acids. A preferred process of preparing the particles is by forming a mixture of magnetic cores with a sol formed from an alcohol and a metal alkoxide, spray-drying the mixture to coat the cores with a layer of gelled sol, and heating the coated cores to obtain the magnetic glass particles. Preferably, the particles have an average particle size of less than 100 ?m. The magnetic core may be a composite material containing a mica core and magnetite particles immobilized on the mica core, and the glass layer may contain boron oxide. Magnetic core materials include magnetite (Fe3O4) and Fe2O3.

Abstract: Magnetic particles with an outer glass surface being essentially poreless or having pores of a diameter of less then 10 nm as well as ferromagnetic particles with a glass surface are preferentially useful for the isolation of biological material from samples. They provide a quick and reliable purification.

Abstract: The invention relates to a divided driver device (5) for a slip ring seal to be mounted in a rotationally fixed manner on a rotating part and serving to transfer a rotatory force to a slip ring (2) that is held in a rotationally fixed manner on the driver device. The driver device (5) is divided in at least one radial plane while forming circle segment-shaped sections that can be joined to one another to form a circular shape, and is also axially subdivided into a divided retaining ring (14) for the slip ring (2) and into a divided mounting ring (16) for mounting in a rotationally fixed manner on the rotating part. The rings (14, 16) are intercoupled as indicated by (24) so that they rotate together. The retaining ring (14) has circle segment-shaped sections (141, 142), which are sealed from one another, can be joined to from an annular shape having a radial inner dimension that is greater than the radial outer nominal dimension of the relevant rotating part (6).

Abstract: Magnetic particles with an outer glass surface being essentially poreless or having pores of a diameter of less then 10 nm as well as ferromagnetic particles with a glass surface are preferentially useful for the isolation of biological material from samples. They provide a quick and reliable purification.

Abstract: This invention relates to magnetic particles having a glass surface which are substantially spherical. This invention also relates to methods for making them, as well as to suspensions thereof and their uses for the purification of DNA or RNA in particular in automated processes.

Abstract: Preparations of particles having a glass surface, wherein more than 75% by weight of these particles have a particle size between 0.5 ?m and 15 ?m and a glass surface which contains between 2 and 6 mole % zinc oxide, have proven to be particularly advantageous in processes for the purification of nucleic acids. This in particular results in an increased nucleic acid yield.

Abstract: Magnetic particles are prepared containing a magnetic core coated with a glass layer having a substantially pore-free class surface or having pores with a diameter offices than 10 nm. The particles are used for separating biological material such as nucleic acids. A preferred process of preparing the particles is by forming a mixture of magnetic cores with a sol formed from an alcohol and a metal alkoxide, spray-drying the mixture to coat the cores with a layer of gelled sol, and heating the coated cores to obtain the magnetic glass particles. Preferably, the particles have an average particle size of less than 100 ?m. The magnetic core may be a composite material containing a mica core and magnetite particles immobilized on the mica core, and the glass layer may contain boron oxide. Magnetic core materials include magnetite (Fe3O4) and Fe2O3.

Abstract: This invention relates to magnetic particles having a glass surface which are substantially spherical. This invention also relates to methods for making them, as well as to suspensions thereof and their uses for the purification of DNA or RNA in particular in automated processes.

Abstract: A seal element of a face seal device for sealing a rotary component relative to a stationary component, includes a pair of mounting portions spaced apart from each other and a bellows portion connected with and extending between the mounting portions. One of the mounting portions serves for non-rotational mounting on the rotary component and the other for mounting a seal ring thereon. At least the surfaces of the mounting and bellows portions which are subjected to a medium which is to be sealed are formed of a synthetic material essentially resistant to the medium. The one mounting portion includes at least a single screw bore essentially radially extending therethrough. A screw pin made of a ceramic material is inserted in the screw bore for clamping the mounting portion relative to the rotary component.