Patents by Inventor Michael Robert Barbachyn

Michael Robert Barbachyn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tricyclic tetrahydroquinoline antibacterial agents
    Patent number: 8420646
    Abstract: The present invention is directed to tricyclic tetrahydroquinoline compounds of formula I, and pharmaceutically acceptable salts thereof wherein the variables R1, R2, R3, R4, R5, R20 and X are as described herein and to pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: April 16, 2013
    Assignee: PAH P&U LLC
    Inventors: Michael Robert Barbachyn, Paul Joseph Dobrowolski, Alexander Ross Hurd, Dennis Joseph McNamara, John Raymond Palmer, Arthur Glenn Romero, J. Craig Ruble, Debra Ann Sherry, Lisa Marie Thomasco, Peter Laurence Toogood
  • Tricyclic Tetrahydroquinoline Antibacterial Agents
    Publication number: 20110092494
    Abstract: The invention includes tetrahydroquinoline and related compounds of formula I, and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens.
    Type: Application
    Filed: December 20, 2010
    Publication date: April 21, 2011
    Inventors: Michael Robert Barbachyn, J. Craig Ruble, Arthur Glenn Romero, Lisa Marie Thomasco, Alexander Ross Hurd, John Raymond Palmer, Peter Laurence Toogood, Dennis Joseph McNamara, Debra Ann Sherry, Paul Joseph Dobrowolski
  • TRICYCLIC TETRAHYDROQUINOLINE ANTIBACTERIAL AGENTS
    Publication number: 20100022524
    Abstract: The invention includes tetrahydroquinoline and related compounds of formula I, and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens.
    Type: Application
    Filed: August 28, 2009
    Publication date: January 28, 2010
    Inventors: Michael Robert Barbachyn, J. Craig Ruble, Arthur Glenn Romero, Lisa Marie Thomasco, Alexander Ross Hurd, John Raymond Palmer, Peter Laurence Toogood, Dennis Joseph McNamara, Debra Ann Sherry, Paul Joseph Dobrowolski
  • Tricyclic tetrahydroquinoline antibacterial agents
    Patent number: 7605157
    Abstract: The invention includes tetrahydroquinoline and related compounds of formula I and pharmaceutical compositions thereof, that exhibit useful antibacterial activity again a wide range of human and veterinary pathogens
    Type: Grant
    Filed: March 7, 2007
    Date of Patent: October 20, 2009
    Assignee: Pharmacia & Upjohn Company LLC
    Inventors: Michael Robert Barbachyn, J. Craig Ruble, Arthur Glenn Romero, Lisa Marie Thomasco, Alexander Ross Hurd, John Raymond Palmer, Peter Laurence Toogood, Dennis Joseph McNamara, Debra Ann Sherry, Paul Joseph Dobrowolski
  • Tricyclic tetrahydroquinoline antibacterial agents
    Patent number: 7208490
    Abstract: The invention includes tetrahydroquinoline and related compounds of formula I, and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens
    Type: Grant
    Filed: October 2, 2003
    Date of Patent: April 24, 2007
    Assignee: Pharmacia & Upjohn Company LLC
    Inventors: Michael Robert Barbachyn, Gordan L. Bundy, Paul Joseph Dobrowolski, Alexander Ross Hurd, Gary E. Martin, Dennis Joseph McNamara, John Raymond Palmer, Donna L. Romero, Arthur Glenn Romero, J. Craig Ruble, Debra Ann Sherry, Lisa Marie Thomasco, Peter Laurence Toogood
  • N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
    Patent number: 7141588
    Abstract: The present invention provides antibacterial agents having the formulae I, II, and III described herein.
    Type: Grant
    Filed: August 22, 2003
    Date of Patent: November 28, 2006
    Assignee: Pfizer, Inc.
    Inventors: Richard Charles Thomas, Toni-Jo Poel, Michael Robert Barbachyn, Mikhail Fedor Gordeev, Gary W. Luehr, Adam Renslo, Upinder Singh, Vara Prasad Venkata Nagendra Josyula
  • N-Aryl-2-oxazolidinone-5-carboxamides and their derivatives
    Patent number: 6919329
    Abstract: The present invention provides antibacterial agents having the formulae I, II, and III described herein.
    Type: Grant
    Filed: February 24, 2003
    Date of Patent: July 19, 2005
    Assignee: Pharmacia & Upjohn Company
    Inventors: Richard Charles Thomas, Toni-Jo Poel, Michael Robert Barbachyn, Mikhail F. Gordeev, Gary W. Luehr, Adam Renslo, Upinder Singh
  • Bicyclic isoxazolinones as antibacterial agents
    Patent number: 6825225
    Abstract: The present invention provides compounds of formula I useful as anti microbial agents wherein X, Y, R1, and n are as defined in thereof.
    Type: Grant
    Filed: November 14, 2001
    Date of Patent: November 30, 2004
    Assignee: Pharmacia & Upjohn Company
    Inventors: Michael J. Genin, Michael Robert Barbachyn, Jackson B. Hester, Jr., Paul D. Johnson, Fred L. Ciske
  • Tricyclic tetrahydroquinoline antibacterial agents
    Publication number: 20040162279
    Abstract: The invention includes tetrahydroquinoline and related compounds of formula I, and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens.
    Type: Application
    Filed: October 2, 2003
    Publication date: August 19, 2004
    Inventors: Michael Robert Barbachyn, J. Craig Ruble, Arthur Glenn Romero, Lisa Marie Thomasco, Alexander Ross Hurd, John Raymond Palmer, Peter Laurence Toogood, Dennis Joseph McNamara, Debra Ann Sherry, Paul Joseph Dobrowolski
  • N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
    Publication number: 20040147760
    Abstract: The present invention provides antibacterial agents having the formulae I, II, and III described herein.
    Type: Application
    Filed: August 22, 2003
    Publication date: July 29, 2004
    Inventors: Richard Charles Thomas, Toni-Jo Poel, Michael Robert Barbachyn, Mikhail Fedor Gordeev, Gary W. Luehr, Adam Renslo, Upinder Singh, Vara Prasad Venkata Nagendra Josyula
  • Novel bicyclic isoxazolinones as antibacterial agents
    Publication number: 20040116413
    Abstract: The present invention provides compounds of formula I useful as antimicrobial agents 1
    Type: Application
    Filed: November 14, 2001
    Publication date: June 17, 2004
    Inventors: Michael J. Genin, Michael Robert Barbachyn, Jackson B. Hester, Paul D. Johnson, Fred L. Ciske
  • N-Aryl-2-oxazolidinone-5-carboxamides and their derivatives
    Publication number: 20040044052
    Abstract: The present invention provides antibacterial agents having the formulae I, II, and III described herein.
    Type: Application
    Filed: February 24, 2003
    Publication date: March 4, 2004
    Inventors: Richard Charles Thomas, Toni-Jo Poel, Michael Robert Barbachyn, Mikhail F. Gordeev, Gary W. Luehr, Adam Renslo, Upinder Singh
  • Thizaine oxazolidinone
    Patent number: 6605609
    Abstract: The present invention provides a thizaine oxazolidinone useful as antimicrobial.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: August 12, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Michael Robert Barbachyn, Gary Edward Zurenko
  • Thiazine oxazolidinone
    Publication number: 20020156072
    Abstract: The present invention provides a thizaine oxazolidinone useful as antimicrobial.
    Type: Application
    Filed: June 15, 2001
    Publication date: October 24, 2002
    Inventors: Michael Robert Barbachyn, Gary Edward Zurenko
  • Novel bicyclic oxazolidinones as antibacterial agents
    Publication number: 20020143009
    Abstract: The present invention provides compounds of formula I useful as antimicrobial agents 1
    Type: Application
    Filed: March 4, 2002
    Publication date: October 3, 2002
    Applicant: Pharmacia & Upjohn
    Inventors: Michael J. Genin, Michael Robert Barbachyn, Jackson B. Hester, Paul D. Johnson
  • Bicyclic oxazolidinones as antibacterial agents
    Patent number: 6387896
    Abstract: The present invention provides compounds of formula I useful as antimicrobial agents wherein W, X, Y, R1, R2 and n are as defined in thereof.
    Type: Grant
    Filed: May 17, 2000
    Date of Patent: May 14, 2002
    Assignee: Pharmacia & Upjohn Co.
    Inventors: Michael J. Genin, Michael Robert Barbachyn, Jackson B. Hester, Jr., Paul D. Johnson
  • Polyaromatic antiviral compositions
    Patent number: 6147116
    Abstract: The present invention relates to polyaromatic compounds having useful antiviral activity against viruses of the herpes family, to a composition containing them, and to a method of using them for the treatment of herpes viruses infections.
    Type: Grant
    Filed: May 11, 1999
    Date of Patent: November 14, 2000
    Assignee: Pharmacia & Upjohn Company
    Inventors: Michael Robert Barbachyn, Fred L. Homa, Antonio Monge, Esteban Santiago, Juan J. Martinez-Irujo, Maria Font
  • Isoxazoline derivatives useful as antimicrobials
    Patent number: 6093736
    Abstract: The present invention provides compounds of formula I ##STR1## or a pharmaceutical acceptable salt thereof wherein Q, X, Y and R.sub.1 are as defined in the claims which are antibacterial agents.
    Type: Grant
    Filed: August 31, 1999
    Date of Patent: July 25, 2000
    Assignee: Pharmacia & Upjohn Company
    Inventors: Michael Robert Barbachyn, Richard Charles Thomas, Gary J. Cleek
  • Spirocyclic and bicyclic diazinyl and carbazinyl oxazolidinones
    Patent number: 6090820
    Abstract: A compound of structural Formula I or II which is useful for treating microbial infections in humans or other warm-blooded animals, or pharmaceultically acceptable salts thereof as defined herein.
    Type: Grant
    Filed: November 7, 1997
    Date of Patent: July 18, 2000
    Assignee: Pharmacia & Upjohn Company
    Inventors: Michael Robert Barbachyn, Steven Joseph Brickner, Douglas K. Hutchinson
  • S-oxide and S,S-dioxide tetrahydrothiopyran phenyloxazolidinones
    Patent number: 6083967
    Abstract: The present invention provides compounds of formula I and formula II useful as antimicrobial agents wherein R.sub.1 is methyl, ethyl, cyclopropyl, or dichloromethyl; R.sub.2 and R.sub.3 are independently hydrogen or fluoro; R.sub.4 is ethyl or dichloromethyl. The invention also relates to a novel assay for determining the inhibitory activity of oxazolidinones to human monoamine oxidase.
    Type: Grant
    Filed: November 20, 1998
    Date of Patent: July 4, 2000
    Assignee: Pharmacia & Upjohn Company
    Inventors: Toni-Jo Poel, Joseph Patrick Martin, Jr., Michael Robert Barbachyn