Patents by Inventor Michael Robert Cancilla

Michael Robert Cancilla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid molecule
    Patent number: 7186550
    Abstract: The present invention is directed generally to an isolated nucleic acid molecule encompassing a neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof and its use inter alia in developing a range of eukaryotic artificial chromosomes including mammalian (e.g. human) and non-mammalian an artificial chromosomes. Such artificial chromosomes are useful in a range of genetic therapies.
    Type: Grant
    Filed: December 2, 2000
    Date of Patent: March 6, 2007
    Assignee: Murdoch Childrens Research Institute
    Inventors: Kong-Hong Andy Choo, Desiree Du Sart, Michael Robert Cancilla
  • In vitro translation system
    Publication number: 20040235029
    Abstract: In vitro translation (IVT) systems and methods for increased expression of proteins from linear templates, using GamS, are provided. The proteins may be full length or protein fragments. The IVT system may be used in batch or continuous mode. The GamS may be used as GamS nucleic acid template, crude protein fraction, or purified protein product. The IVT system using GamS component may be employed in a high-throughput mode. The ability to predict expressible protein or fragments, and activity and solubility of a large-scale protein expression product based on the results obtained from high-throughput, small-scale IVT expression product is also provided.
    Type: Application
    Filed: April 27, 2004
    Publication date: November 25, 2004
    Inventors: Jae Moon Lee, Douglas Iwen Buckley, Michael Robert Cancilla, Damian E. Curtis, Krista K. Bowman, Hangjun Zhan, Margie Ciancio
  • Novel nucleic acid molecule
    Publication number: 20030096398
    Abstract: The present invention is directed generally to an isolated nucleic acid molecule encompassing a neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof and its use inter alia in developing a range of eukaryotic artificial chromosomes including mammalian (e.g. human) and non-mammalian an artificial chromosomes. Such artificial chromosomes are useful in a range of genetic therapies.
    Type: Application
    Filed: December 2, 2000
    Publication date: May 22, 2003
    Inventors: Kong-Hong Andy Choo, Desiree Du Sart, Michael Robert Cancilla
  • Nucleic acid molecules comprising a neocentromere
    Patent number: 6265211
    Abstract: The present invention is directed generally to an isolated nucleic acid molecule encompassing a neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof and its use inter alia in developing a range of eukaryotic artificial chromosomes including mammalian (e.g. human) and non-mammalian artificial chromosomes. Such artificial chromosomes are useful in a range of genetic therapies.
    Type: Grant
    Filed: May 13, 1998
    Date of Patent: July 24, 2001
    Assignee: AMRAD Operations Pty. Ltd.
    Inventors: Kong-Hong Andy Choo, Desiree Du Sart, Michael Robert Cancilla