Patents by Inventor MICHAEL ROBERT KIERNY

MICHAEL ROBERT KIERNY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNE REPERTOIRE MINING
    Publication number: 20240150437
    Abstract: The present invention provides a method for producing encapsulated natively-paired scFv amplicons, by encapsulating single cells in droplets, wherein the droplets further contain reagents for amplifying and sinking native pairings of heavy and light chain variable domain amplicons from single encapsulated cells; lysing the single encapsulated cells; and generating the encapsulated natively-paired scFv amplicons, wherein each scFv amplicon comprises a native pairing of heavy and light chain variable domain amplicons.
    Type: Application
    Filed: October 19, 2023
    Publication date: May 9, 2024
    Inventors: Partha S. CHOWDHURY, Saravanan RAJAN, Michael Robert KIERNY
  • IMMUNE REPERTOIRE MINING
    Publication number: 20190367585
    Abstract: The present invention provides a method for producing encapsulated natively-paired scFv amplicons, by encapsulating single cells in droplets, wherein the droplets further contain reagents for amplifying and sinking native pairings of heavy and light chain variable domain amplicons from single encapsulated cells; lysing the single encapsulated cells; and generating the encapsulated natively-paired scFv amplicons, wherein each scFv amplicon comprises a native pairing of heavy and light chain variable domain amplicons.
    Type: Application
    Filed: April 12, 2017
    Publication date: December 5, 2019
    Inventors: PARTHA S. CHOWDHURY, SARAVANAN RAJAN, MICHAEL ROBERT KIERNY