Patents by Inventor Michael Robert McKeown

Michael Robert McKeown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF STRATIFYING PATIENTS FOR TREATMENT WITH RETINOIC ACID RECEPTOR-ALPHA AGONISTS
    Publication number: 20240102106
    Abstract: Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations.
    Type: Application
    Filed: June 16, 2023
    Publication date: March 28, 2024
    Inventors: Michael Robert McKeown, Christopher M. Fiore, Matthew Lucas Eaton, Emily Payton Lee, Christian Fritz
  • METHODS OF STRATIFYING PATIENTS FOR TREATMENT WITH RETINOIC ACID RECEPTOR-ALPHA AGONISTS
    Publication number: 20230042181
    Abstract: The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.
    Type: Application
    Filed: July 22, 2022
    Publication date: February 9, 2023
    Inventors: Mei Wei Chen, Cindy Collins, Matthew Lucas Eaton, Matthew G. Guenther, Nan Ke, Jeremy Lopez, Michael Robert McKeown, David A. Orlando
  • Methods of stratifying patients for treatment with retinoic acid receptor-alpha agonists
    Patent number: 11447831
    Abstract: The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.
    Type: Grant
    Filed: May 8, 2020
    Date of Patent: September 20, 2022
    Assignee: Syros Pharmaceuticals, Inc.
    Inventors: Mei Wei Chen, Cindy Collins, Matthew Lucas Eaton, Matthew G. Guenther, Nan Ke, Jeremy Lopez, Michael Robert McKeown, David A. Orlando
  • METHODS OF STRATIFYING PATIENTS FOR TREATMENT WITH RETINOIC ACID RECEPTOR-ALPHA AGONISTS
    Publication number: 20210285059
    Abstract: Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations.
    Type: Application
    Filed: June 1, 2021
    Publication date: September 16, 2021
    Inventors: Michael Robert McKeown, Christopher M. Fiore, Matthew Lucas Eaton, Emily Payton Lee, Christian Fritz
  • Methods of stratifying patients for treatment with retinoic acid receptor-? agonists
    Patent number: 11053552
    Abstract: Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: July 6, 2021
    Assignee: Syros Pharmaceuticals, Inc.
    Inventors: Michael Robert McKeown, Christopher Fiore, Matthew Lucas Eaton, Emily Payton Lee, Christian Fritz
  • METHODS OF STRATIFYING PATIENTS FOR TREATMENT WITH RETINOIC ACID RECEPTOR-ALPHA AGONISTS
    Publication number: 20200392583
    Abstract: The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.
    Type: Application
    Filed: May 8, 2020
    Publication date: December 17, 2020
    Inventors: Mei Wei Chen, Cindy Collins, Matthew Lucas Eaton, Matthew G. Guenther, Nan Ke, Jeremy Lopez, Michael Robert McKeown, David A. Orlando
  • METHODS OF STRATIFYING PATIENTS FOR TREATMENT WITH RETINOIC ACID RECEPTOR-ALPHA AGONISTS
    Publication number: 20190249259
    Abstract: Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations.
    Type: Application
    Filed: January 14, 2019
    Publication date: August 15, 2019
    Inventors: Michael Robert McKeown, Christopher Fiore, Matthew Lucas Eaton, Emily Payton Lee, Christian Fritz
  • Methods of stratifying patients for treatment with retinoic acid receptor-alpha agonists
    Patent number: 10240210
    Abstract: Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: March 26, 2019
    Assignee: Syros Pharmaceuticals, Inc.
    Inventors: Michael Robert McKeown, Christopher Fiore, Matthew Lucas Eaton, Emily Payton Lee, Christian Fritz
  • METHODS OF STRATIFYING PATIENTS FOR TREATMENT WITH RETINOIC ACID RECEPTOR-ALPHA AGONISTS
    Publication number: 20180155796
    Abstract: Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations.
    Type: Application
    Filed: December 1, 2017
    Publication date: June 7, 2018
    Inventors: Michael Robert McKeown, Christopher Fiore, Matthew Lucas Eaton, Emily Payton Lee, Christian Fritz
  • Methods of stratifying patients for treatment with retinoic acid receptor-? agonists
    Patent number: 9868994
    Abstract: Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: January 16, 2018
    Assignee: Syros Pharmaceuticals, Inc.
    Inventors: Michael Robert McKeown, Christopher Fiore, Matthew Lucas Eaton, Emily Payton Lee, Christian Fritz
  • METHODS OF STRATIFYING PATIENTS FOR TREATMENT WITH RETINOIC ACID RECEPTOR-ALPHA AGONISTS
    Publication number: 20170292165
    Abstract: Described herein are methods that define cellular populations that are sensitive to RARA agonists and identify patient populations that will benefit from treatment with RARA agonists. The methods may comprise administering RARA agonists to patient populations.
    Type: Application
    Filed: April 28, 2017
    Publication date: October 12, 2017
    Inventors: Michael Robert McKeown, Christopher Fiore, Matthew Lucas Eaton, Emily Payton Lee, Christian Fritz