Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1 to R3, A, B, X, Y and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1 to R6, A, B, X, Y and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1 to R6, A, B, X, Y and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

Abstract: Disclosed are compounds of formula (I): wherein R1 and R4 are defined herein, which are useful as inhibitors of the kinase activity of the I?B kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases, cardiovascular disease and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.

Abstract: Disclosed are novel substituted 2H-isoquinolin-1-one and 3H-quinazolin-4-one derivatives useful as inhibitors of Rho kinase and for treating a variety of diseases and disorders that are mediated or sustained through the activity of Rho kinase, including cardiovascular diseases, pharmaceutical compositions comprising such compounds, methods for using such compounds and processes for making such compounds.

Abstract: A memory exhaustion condition is handled in a data processing system having first and second regions of physical memory. The memory exhaustion condition is detected while the second region is mirroring at least part of the first region. In response to the memory exhaustion condition, memory mirroring is at least partially deactivated and at least part of the second region is utilized to augment the first region, such that the memory exhaustion condition is eliminated. In an illustrative embodiment, the data processing system compresses real memory into the first region of physical memory, and the memory exhaustion condition arises when the first region lacks sufficient available capacity to accommodate current requirements for real memory. The memory exhaustion condition is eliminated by compressing at least part of the real memory into the second region.

Abstract: The present invention provides a method and apparatus for enabling or disabling an ISA adapter or bus expansion device. In one embodiment of the invention, the housing slot is first checked to see whether the device is installed. If the device is installed and is malfunctioning or defective, the device is then isolated or disabled to allow the system to continue to operate. In another embodiment of the invention, a check is done to determine whether the housing slot has changed from an empty to a full status and vice versa. This check determines whether configuration status of an adapter, stored in memory, should be deleted. This check also allows for the differentiation of a PNP adapter card from a legacy adapter card.

Abstract: A method for managing a memory address space in a memory system, the memory system having multiple block address translation entries, each entry defining a portion of the memory address space, including the steps of determining that a received virtual address references a portion of the memory address space not defined by any of the block address translation entries, reallocating at least one of the block address translation entries to define a portion of the memory address space including the received virtual address, and providing a physical address matching the virtual address by using the reallocated block address translation entries.

Abstract: A method and apparatus for dynamically selecting adapter card identifiers within a computer system having expansion slots. Name strings used by the computer system, such as in a system using Micro Channel expansion slots, identify the installed adapter card. The method and apparatus distinguish automatically between adapter cards upon installation. This is accomplished by, responsive to identifying a newly installed adapter card, transforming the default POS name string to an alternate identifier. Next, additional random values are added to the transformed alternate identifier to increase identifier uniqueness. Then, portions of the name string are matched to a field within the alternate identifier, before storing the identifier, for allowing the computer to identify the correct alternate identifier matching the newly installed adapter card. The new identifier is stored in both the expansion slot addressing region and on the adapter card.