Abstract: Kits, methods, polypeptides, systems, and non-transitory, machine-readable storage media for detecting a nucleic acid in a sample are described. In an embodiment, the kit comprises a loop primer nucleic acid molecule configured for loop-mediated isothermal amplification (LAMP), the loop primer nucleic acid molecule comprising: a targeting sequence complementary to a target portion of a target nucleic acid sequence; and an adapter sequence; a displacement nucleic acid probe comprising: a fluorophore adapter sequence; and the adapter sequence; and a fluorophore adapter complement nucleic acid molecule complementary to the fluorophore adapter sequence, wherein the fluorophore adapter sequence or the fluorophore adapter complement nucleic acid molecule is coupled to a fluorophore. In an embodiment, the system comprises a thermal subsystem for heating a sample disposed therein, and an optical subsystem for optically excited the sample and detecting light emitted from the sample.

Abstract: A thermal cycling device has been disclosed herein. The device includes an upper housing and a lower housing for housing a plurality of components of the thermal cycling device. The plurality of components comprises at least a plurality of heat blocks, a plurality of tubes, and a heater. The heat block is a thin-walled metallic component that conforms to the contour of the corresponding tube and provides a surface for interfacing with the heater. Further, the heat block is designed to minimize thermal mass in order to reduce power required to achieve desired temperature ramp rates. Further, the heat block is designed such that it should exhibit minimal deflection when preload is applied to the corresponding tube.

Abstract: A testing device for carrying out investigations on a test body, which testing device comprises a rail guide with a slide unit coupled to a drive unit for acceleration, on which slide unit the test body is arranged, wherein the drive unit is connected to a control unit and at least one image capturing unit is provided for capturing image data of the test body. The at least one image capturing unit is arranged on a further slide unit, which is arranged on a further rail guide running parallel to the rail guide of the slide unit of the test body, wherein the further slide unit of the at least one image capturing unit comprises a separate drive unit for accelerating the further slide unit, which drive unit is connected to the control unit. Further, embodiments of the invention relate to a use of such a testing device.

Abstract: A testing device for carrying out investigations on a test body, which testing device comprises a rail guide with a slide unit coupled to a drive unit for acceleration, on which slide unit the test body is arranged, wherein the drive unit is connected to a control unit and at least one image capturing unit is provided for capturing image data of the test body. The at least one image capturing unit is arranged on a further slide unit, which is arranged on a further rail guide running parallel to the rail guide of the slide unit of the test body, wherein the further slide unit of the at least one image capturing unit comprises a separate drive unit for accelerating the further slide unit, which drive unit is connected to the control unit. Further, embodiments of the invention relate to a use of such a testing device.