Patents by Inventor Michael Roller

Michael Roller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230272462
    Abstract: Kits, methods, polypeptides, systems, and non-transitory, machine-readable storage media for detecting a nucleic acid in a sample are described. In an embodiment, the kit comprises a loop primer nucleic acid molecule configured for loop-mediated isothermal amplification (LAMP), the loop primer nucleic acid molecule comprising: a targeting sequence complementary to a target portion of a target nucleic acid sequence; and an adapter sequence; a displacement nucleic acid probe comprising: a fluorophore adapter sequence; and the adapter sequence; and a fluorophore adapter complement nucleic acid molecule complementary to the fluorophore adapter sequence, wherein the fluorophore adapter sequence or the fluorophore adapter complement nucleic acid molecule is coupled to a fluorophore. In an embodiment, the system comprises a thermal subsystem for heating a sample disposed therein, and an optical subsystem for optically excited the sample and detecting light emitted from the sample.
    Type: Application
    Filed: July 9, 2021
    Publication date: August 31, 2023
    Applicant: UNIVERSITY OF WASHINGTON
    Inventors: Enos Kline, Michael Roller, Robert G. Atkinson, Nuttada Panpradist, Daniel Leon, Ian Hull, Qin Wang, Barry R. Lutz
  • Publication number: 20210237088
    Abstract: A thermal cycling device has been disclosed herein. The device includes an upper housing and a lower housing for housing a plurality of components of the thermal cycling device. The plurality of components comprises at least a plurality of heat blocks, a plurality of tubes, and a heater. The heat block is a thin-walled metallic component that conforms to the contour of the corresponding tube and provides a surface for interfacing with the heater. Further, the heat block is designed to minimize thermal mass in order to reduce power required to achieve desired temperature ramp rates. Further, the heat block is designed such that it should exhibit minimal deflection when preload is applied to the corresponding tube.
    Type: Application
    Filed: February 3, 2021
    Publication date: August 5, 2021
    Inventor: Michael Roller
  • Publication number: 20180044772
    Abstract: An apparatus and method for open-atmosphere flame based spraying employs a nozzle to preheat, pressurize and atomize a mechanically pumped reactive and flammable liquid solution through a small orifice or a nozzle and then a set of pilot flames to combust the spray. The liquid feedstock is preheated to a supercritical temperature before reaching the nozzle and is pressurized before spraying due to a reduced size of the outlet port of the feedstock flow channel relative to the inlet. A supplementary collimating, or sheathing, gas is supplied to the flow channel of the feedstock and both the feedstock and the supplementary gas are uniformly heated before spraying. This arrangement helps to avoid clogging of the nozzle and results in satisfactory control of the properties of the particulate products of the spraying procedure.
    Type: Application
    Filed: July 13, 2016
    Publication date: February 15, 2018
    Inventors: Radenka Maric, Thomas P.K. Vanderhoek, Justin Michael Roller
  • Patent number: 9787883
    Abstract: A testing device for carrying out investigations on a test body, which testing device comprises a rail guide with a slide unit coupled to a drive unit for acceleration, on which slide unit the test body is arranged, wherein the drive unit is connected to a control unit and at least one image capturing unit is provided for capturing image data of the test body. The at least one image capturing unit is arranged on a further slide unit, which is arranged on a further rail guide running parallel to the rail guide of the slide unit of the test body, wherein the further slide unit of the at least one image capturing unit comprises a separate drive unit for accelerating the further slide unit, which drive unit is connected to the control unit. Further, embodiments of the invention relate to a use of such a testing device.
    Type: Grant
    Filed: May 7, 2014
    Date of Patent: October 10, 2017
    Assignee: Frontone GmbH
    Inventors: Klaus Matlschweiger, Michael Roller, Bernhard Glaser, Helmut Ruoff
  • Patent number: 9399234
    Abstract: An apparatus and method for open-atmosphere flame based spraying employs a nozzle to preheat, pressurize and atomize a mechanically pumped reactive and flammable liquid solution through a small orifice or a nozzle and then a set of pilot flames to combust the spray. The liquid feedstock is preheated to a supercritical temperature before reaching the nozzle and is pressurized before spraying due to a reduced size of the outlet port of the feedstock flow channel relative to the inlet. A supplementary collimating, or sheathing, gas is supplied to the flow channel of the feedstock and both the feedstock and the supplementary gas are uniformly heated before spraying. This arrangement helps to avoid clogging of the nozzle and results in satisfactory control of the properties of the particulate products of the spraying procedure.
    Type: Grant
    Filed: October 17, 2006
    Date of Patent: July 26, 2016
    Assignee: National Research Council of Canada
    Inventors: Radenka Maric, Thomas P. K. Vanderhoek, Justin Michael Roller
  • Publication number: 20160119511
    Abstract: A testing device for carrying out investigations on a test body, which testing device comprises a rail guide with a slide unit coupled to a drive unit for acceleration, on which slide unit the test body is arranged, wherein the drive unit is connected to a control unit and at least one image capturing unit is provided for capturing image data of the test body. The at least one image capturing unit is arranged on a further slide unit, which is arranged on a further rail guide running parallel to the rail guide of the slide unit of the test body, wherein the further slide unit of the at least one image capturing unit comprises a separate drive unit for accelerating the further slide unit, which drive unit is connected to the control unit. Further, embodiments of the invention relate to a use of such a testing device.
    Type: Application
    Filed: May 7, 2014
    Publication date: April 28, 2016
    Inventors: Klaus Matlschweiger, Michael Roller, Bernhard Glaser, Helmut Ruoff
  • Publication number: 20080280056
    Abstract: An apparatus and method for open-atmosphere flame based spraying employs a nozzle to preheat, pressurize and atomize a mechanically pumped reactive and flammable liquid solution through a small orifice or a nozzle and then a set of pilot flames to combust the spray. The liquid feedstock is preheated to a supercritical temperature before reaching the nozzle and is pressurized before spraying due to a reduced size of the outlet port of the feedstock flow channel relative to the inlet. A supplementary collimating, or sheathing, gas is supplied to the flow channel of the feedstock and both the feedstock and the supplementary gas are uniformly heated before spraying. This arrangement helps to avoid clogging of the nozzle and results in satisfactory control of the properties of the particulate products of the spraying procedure.
    Type: Application
    Filed: October 17, 2006
    Publication date: November 13, 2008
    Inventors: Radenka Maric, Thomas P.K. Vanderhoek, Justin Michael Roller