Abstract: A method and apparatus for cleansing the interior surfaces of body cavities employs a balloon catheter adapted to be inserted into a cavity through its ostium with the balloon in collapsed condition. An input flow tube for a cleansing and/or medicating fluid passes through a central passage in the balloon. When the balloon is inflated to establish a narrow passage between the balloon and the cavity walls, a pressurized flow of the fluid is pumped out the distal end of the input flow tube through the passage, parallel to the cavity walls, where it scours the inner wall of the cavity, removing debris as it flows out of the ostium. The fluid flow is urged toward a turbulent condition by attachments to the outer wall of the balloon.

Abstract: A method and apparatus for cleansing the interior surfaces of body cavities employs a balloon catheter adapted to be inserted into a cavity through its ostium with the balloon in collapsed condition. An input flow tube for a cleansing and/or medicating fluid passes through a central passage in the balloon. When the balloon is inflated to establish a narrow passage between the balloon and the cavity walls, a pressurized flow of the fluid is pumped out the distal end of the input flow tube through the passage, parallel to the cavity walls, where it scours the inner wall of the cavity, removing debris as it flows out of the ostium. The fluid flow is urged toward a turbulent condition by attachments to the outer wall of the balloon.

Abstract: A piezo-driven, vibrating beam is applicable to surgical procedures. A rod of piezoelectric material defines a length with proximal and distal ends. A pattern of electrodes, disposed adjacent to and along the length of the rod of piezoelectric material, is adapted for connection to a generator operative to stimulate the piezoelectric material, causing the rod to assume one or more vibratory states. In preferred embodiments, the proximal end of the rod of piezoelectric material is adapted for coupling to a blocking mass causing the vibratory states to be concentrated at the distal end of the rod of piezoelectric material. The pattern of electrodes may comprise interdigitated fingers, and the system may further include a material encapsulating the rod and the pattern of electrodes. Preferred embodiments may further include a plurality of coextensive, parallel rods forming a basic unit, each rod having a separate pattern of electrodes adjacent thereto.

Abstract: A method and apparatus for cleansing the interior surfaces of body cavities employs a balloon catheter adopted to be inserted into a cavity through its ostium with the balloon in collapsed condition. An input flow tube for a cleansing and/or medicating fluid passes through a central passage in the balloon. When the balloon is inflated to establish a narrow passage between the balloon and the cavity walls, a pressurized flow of the fluid is pumped out the distal end of the input flow tube through the passage, parallel to the cavity walls, where it scours the inner wall of the cavity, removing debris as it flows out of the ostium. The fluid flow is urged toward a turbulent condition by attachments to the outer wall of the balloon.

Abstract: A surgical instrument for treating body tissues through narrow body passages employs an elongated cantilevered beam having a proximal end supported in a rigid block and a narrower distal end extendable through the narrow passages. One or more piezoelectric actuators are fixed to the beam surface and energized from an AC source provided by an electrical excitation system through electrodes interspersed with the piezoelectric actuators to produce oscillatory motion of the beam distal end in multiple modes of movement.

Abstract: Electrical feedback is provided to a user who cannot receive full sensation from a body part due to amputation, neuropathy or other condition. A sensor array includes an array of capacitive force-sensing elements operative to sense axial and shear forces applied to that element. Temperature may also be sensed at each force-sensor location. An electrode matrix, adapted for external placement in an area on a user of the sensor array, includes an array of electrodes in physical correspondence to the array of capacitive sensing elements of the sensor array. An electronic controller is configured to receive electrical signals representative of the axial and shear forces applied to the sensor array and drive the electrode matrix with electrical stimulation signals corresponding to the electrical signals received from the sensor array, thereby enabling the user to experience force and/or temperature sensations experienced by the body part through the electrode matrix.

Abstract: A tissue-modifying catheter adapted for use with an MRI machine includes an elongated hollow sheath configured for intraluminal introduction with proximal and distal open ends. A coil of electrically conductive, non-magnetic wire, disposed at the proximal open end of the sheath is in electrical communication with an electrical waveform generator through a set of electrical conductors entering into the open proximal end of the sheath. A non-magnetic end effector is physically or mechanically coupled to the coil of wire, such that when a voltage is imposed upon the coil of wire through the waveform generator, the coil experiences a directional torque due to the presence of the MRI-oriented magnetic field, causing the end effector to interact with surrounding tissue. The waveform generator preferably delivers a time-varying waveform such as sinusoid that may be synchronized with the MRI-oriented magnetic field. The catheter may include a plurality of different end effectors for different application.

Abstract: A piezo-driven, vibrating beam is applicable to surgical procedures. A rod of piezoelectric material defines a length with proximal and distal ends. A pattern of electrodes, disposed adjacent to and along the length of the rod of piezoelectric material, is adapted for connection to a generator operative to stimulate the piezoelectric material, causing the rod to assume one or more vibratory states. In preferred embodiments, the proximal end of the rod of piezoelectric material is adapted for coupling to a blocking mass causing the vibratory states to be concentrated at the distal end of the rod of piezoelectric material. The pattern of electrodes may comprise interdigitated fingers, and the system may further include a material encapsulating the rod and the pattern of electrodes. Preferred embodiments may further include a plurality of coextensive, parallel rods forming a basic unit, each rod having a separate pattern of electrodes adjacent thereto.

Abstract: A surgical instrument for treating body tissues through narrow body passages employs an elongated cantilevered beam having a proximal end supported in a rigid block and a narrower distal end extendable through the narrow passages. One or more piezoelectric actuators are fixed to the beam surface and energized from an AC source provided by an electrical excitation system through electrodes interspersed with the piezoelectric actuators to produce oscillatory motion of the beam distal end in multiple modes of movement.

Abstract: Electrical feedback is provided to a user who cannot receive full sensation from a body part due to amputation, neuropathy or other condition. A sensor array includes an array of capacitive force-sensing elements operative to sense axial and shear forces applied to that element. Temperature may also be sensed at each force-sensor location. An electrode matrix, adapted for external placement in an area on a user of the sensor array, includes an array of electrodes in physical correspondence to the array of capacitive sensing elements of the sensor array. An electronic controller is configured to receive electrical signals representative of the axial and shear forces applied to the sensor array and drive the electrode matrix with electrical stimulation signals corresponding to the electrical signals received from the sensor array, thereby enabling the user to experience force and/or temperature sensations experienced by the body part through the electrode matrix.

Abstract: A surgical instrument for treating body tissues through narrow body passages employs an elongated cantilevered beam having a proximal end supported in a rigid block and a narrower distal end extendable through the narrow passages. One or more piezoelectric actuators are fixed to the beam surface and energized from an AC source through electrodes interspersed with the piezoelectric actuators to produce oscillatory motion of the beam distal end in multiple modes of movement with sensing electronics to monitor and control the distal mechanical movement.

Abstract: A surgical instrument for treating body tissues through narrow body passages employs an elongated cantilevered beam having a proximal end supported in a rigid block and a narrower distal end extendable through the narrow passages. One or more piezoelectric actuators are fixed to the beam surface and energized from an AC source through electrodes interspersed with the piezoelectric actuators to produce oscillatory motion of the beam distal end in multiple modes of movement with sensing electronics to monitor and control the distal mechanical movement. The oscillatory beam is assisted with cold plasma sterilization of the target tissue surface to be treated at the distal end.

Abstract: A surgical instrument for treating body tissues through narrow body passages employs an elongated cantilevered beam having a proximal end supported in a rigid block and a narrower distal end extendable through the narrow passages. One or more piezoelectric actuators are fixed to the beam surface and energized from an AC source through electrodes interspersed with the piezoelectric actuators to produce oscillatory motion of the beam distal end in multiple modes of movement with sensing electronics to monitor and control the distal mechanical movement.

Abstract: To treat body surfaces, such as the sinuses, which are coated with biofilms, the surface is irrigated and suctioned with a fluid which may contain a biocide or other chemical agent for disrupting the biofilm while ultrasonic energy is applied to either the fluid barrier formed over the biofilm or a body surface proximal to the biofilm. Action of the fluid enhanced by the ultrasonic energy tends to remove sections of biofilm which are suctioned out of the site. An electrical field may also be applied to the biofilm to enhance the disruptive action. Apparatus for practicing this method to treat chronic rhinosinusitis comprises an elongated tube adapted to be inserted into sinus cavities through the nose or mouth. The tube includes a first lumen which feeds an irrigating fluid containing biocides and/or biofilm-disruptive chemicals to the treatment site and a second lumen which suctions fluid from the site.

Abstract: Chronic sinusitis is treated by the application of cold plasma or plasma-activated species to the infected mucosal surfaces through use of an endoscope having a steerable end which may be projected into the sinus cavities through the nasal cavity. The cold plasma is generated at either the distal end of the endoscope with a power source by application of a power, or at the distal end by gas and electrical connections extending through the endoscope. The cold plasma or plasma-activated species act to destroy bacterial cells but not eukaryotic cells.

Abstract: Embodiments isolate exposed surfaces to increase the effectiveness of different treatment modalities. Embodiments isolate hollow spaces within the body to increase the effectiveness of ultrasound energy and/or other treatments. Such hollow spaces within the body may include nasal surfaces, and recessed or sequestered surfaces, e.g. sinus cavity surfaces or other anatomical structures, such as upper and lower gastrointestinal tract, airways, uterine and vaginal cavities and the anorectal canal, for example. Isolating the area to be treated reduces the volume of the enclosed and delimited space and reduces the tissue surface against which the ultrasound and/or biologically active substances act. For example, isolating a hollow passageway within the body enhances the effectiveness of ultrasound within the isolated space, and constrains the biologically active fluid and/or the gel or fluid configured to conducts the ultrasonic energy from the emitter thereof (e.g.

Abstract: A method and apparatus for cleansing the interior surfaces of body cavities employs a balloon catheter adopted to be inserted into a cavity through its ostium with the balloon in collapsed condition. An input flow tube for a cleansing and/or medicating fluid passes through a central passage in the balloon. When the balloon is inflated to establish a narrow passage between the balloon and the cavity walls, a pressurized flow of the fluid is pumped out the distal end of the input flow tube through the passage, parallel to the cavity walls, where it scours the inner wall of the cavity, removing debris as it flows out of the ostium. The fluid flow is urged toward a turbulent condition by attachments to the outer wall of the balloon.

Abstract: Devices, systems and methods using low frequency ultrasound to emulsify, disintegrate, cut and/or coagulate tissue in a narrow space such as the nasal passages and paranasal sinuses. The devices may comprise a low frequency generator, a functionally active handle, an ultrasound emitter, a concentrator, a waveguide and distal functional tips. The devices and methods are configured to safely and efficiently carry out surgical procedures within the nose and sinuses, among other soft tissues within the body.

Abstract: Chronic sinusitis is treated by the application of cold plasma or plasma-activated species to the infected mucosal surfaces through use of an endoscope having a steerable end which may be projected into the sinus cavities through the nasal cavity. The cold plasma is generated at either the distal end of the endoscope with a power source by application of a power, or at the distal end by gas and electrical connections extending through the endoscope. The cold plasma or plasma-activated species act to destroy bacterial cells but not eukaryotic cells.

Abstract: Chronic sinusitis is treated by the application of cold plasma or plasma-activated species to the infected mucosal surfaces through use of an endoscope having a steerable end which may be projected into the sinus cavities through the nasal cavity. The cold plasma is generated at either the distal end of the endoscope with a power source by application of a power, or at the distal end by gas and electrical connections extending through the endoscope. The cold plasma or plasma-activated species act to destroy bacterial cells but not eukaryotic cells.