Abstract: A curable silicone rubber composition of the type referred to in industry as “self-adhesive” or as having “selective adhesion” (hereafter referred to as “curable self-adhesive silicone rubber compositions”). The curable self-adhesive silicone rubber compositions comprise: (A) one or more organopolysiloxanes containing at least 2 alkenyl groups and/or alkynyl groups per molecule and having a viscosity in a range of 1000 mPa·s to 200,000 mPa·s at 25° C.; (B) an organopolysiloxane containing at least 2 or 3 silicon-bonded hydrogen atoms per molecule; (C) at least one hydrosilylation catalyst; (D) at least one reinforcing and optionally one or more non-reinforcing fillers; (E) an adhesion promoter; and (F) an oligomer which has been found to surprisingly provide heat-humidity stabilization.

Abstract: Embodiments described herein are generally directed to improving predictions regarding workload performance to facilitate dynamic auto device selection. In an example, based on telemetry samples collected from a computer system in real-time and indicative of a state of the computer system, one or more workload performance prediction models are built or updated for a heterogeneous set of computer resources of the computer system with reference to one or more optimization goals. At a time of execution of a workload, a particular computer resource of the heterogeneous set of computer resources on which to dispatch the workload is dynamically determined by: (i) generating multiple predicted performance scores each corresponding to one of the computer resources based on the state of the computer system and the one or more workload performance prediction models; and (ii) selecting the particular computer resource based on the predicted performance scores.

Abstract: Methods, apparatus, systems, and articles of manufacture for enhancing a video and audio experience are disclosed. Example apparatus disclosed herein detect a first visual object in a visual stream of a multimedia stream, the first visual object associated with a first location in a content creation space represented by the multimedia stream, and detect a first audio object in an audio stream of the multimedia stream, the first audio object associated with a second location in the content creation space. Disclosed example apparatus also evaluate a correlation between the first visual object and the first audio object, the correlation based on the first location and the second location. Disclosed example apparatus further generate metadata for the multimedia stream based on the correlation between the first visual object and the first audio object.

Abstract: Example smart panel display apparatus and related methods are disclosed herein. An example apparatus to control a display of an electronic device includes a user presence detector to determine a presence of a user relative to the device based on image data generated by an image sensor of the device. The example apparatus includes a gaze detector to determine a direction of a gaze of the user relative to the image sensor based on the image data. The example apparatus includes a backlight manager to selectively adjust a display brightness based on the presence of the user and the direction of the gaze of the user.

Abstract: Methods, systems, and apparatus to reconfigure a computer are disclosed. An example electronic device includes at least one memory, instructions in the electronic device, and processor circuitry to execute instructions to analyze data corresponding to a first configuration of the electronic device to detect a change associated with the electronic device, the first configuration corresponding to a respective first user profile, determine a second configuration of the electronic device based on the detected change, and adjust a configuration of the electronic device from the first configuration to the second configuration.

Abstract: Systems and methods for applying style transfer functions in multi-camera systems and multi-microphone systems are disclosed herein. An example multi-camera style transfer system includes at least one memory, instructions in the system, and processor circuitry to execute the instructions to at least apply a style transfer function to a second image from a second video feed to generate a stylized image based on a reference image. The reference image corresponds to a first image from a first video feed. The first video feed is from a first camera. The second video feed is from a second camera. The processor circuitry also executed the instructions to adjust one or more parameter settings of a video filter based on the stylized image, and filter the second video feed using the video filter with the adjusted parameter settings to generate a filtered version of the second video feed.

Abstract: The present disclosure is directed to a computing device including one or more processors and a foldable display. A non-transitory computer-readable medium stores a set of instructions that when executed by at least one processor of the one more processors cause the at least one processor to detect a usage mode of the foldable electronic device, detect user input to the foldable electronic device, and control a brightness of an active area on the display based on the detected usage mode and detected user input.

Abstract: Apparatus, systems, and methods for audio and video filtering for electronic user devices are disclosed. An example apparatus includes at least one memory, instructions in the apparatus, and processor circuitry to execute instructions to detect a visual event based on image data, the visual event representative of an activity associated with a likelihood of noise, the image data associated with a video stream output by a camera associated with a user device, and in response to the detection of the visual event, apply an audio filter to a portion of an audio stream corresponding to the image data in the video stream.

Abstract: The present invention relates to methods of treating a cell proliferation disorder (e.g., cancer) comprising administering: (a) a compound having the Formula (I), wherein R1 or R2 are as herein defined, or a pharmaceutically acceptable salt thereof; and (b) an anti-human PD-1 antibody or antigen binding fragment thereof to a human patient in need thereof. Also disclosed are therapeutic combinations and kits containing such agents for the treatment of cancers.

Abstract: Disclosed herein are flexible display panels and bend detection circuits for flexible display panels where the bend detection circuit can be formed on a flexible substrate of the flexible display panel stack. The bend detection circuit including a number of sensor elements arranged to change an electric response to an applied electric signal based on an applied physical force. The bend detection circuits also including a bend sensing circuit arranged to measure a time delay of the number of sensor elements to the applied electric signal.

Abstract: The present disclosure is directed to a computing device including one or more processors and a foldable display. A non-transitory computer-readable medium stores a set of instructions that when executed by at least one processor of the one more processors cause the at least one processor to detect a usage mode of the foldable electronic device, detect user input to the foldable electronic device, and control a brightness of an active area on the display based on the detected usage mode and detected user input.

Abstract: The present invention relates to methods of treating a cell proliferation disorder (e.g., cancer) comprising administering: (a) a compound having the Formula (I), wherein R1 or R2 are as herein defined, or a pharmaceutically acceptable salt thereof; and (b) an anti-human PD-1 antibody or antigen binding fragment thereof to a human patient in need thereof. Also disclosed are therapeutic combinations and kits containing such agents for the treatment of cancers.

Abstract: The receptor for VISTA is identified (VSIG8) as well as the use of this receptor in the identification or synthesis of agonist or antagonist compounds, preferably antibodies, polypeptides and fusion proteins which agonize or antagonize the effects of VSIG8 and/or VISTA and/or the VSIG8/VISTA binding interaction. These antagonists may be used to suppress VISTA's suppressive effects on T cell immunity, and more particularly used in the treatment of cancer, or infectious disease. These agonist compounds may be used to potentiate or enhance VISTA's suppressive effects on T cell immunity and thereby suppress T cell immunity, such as in the treatment of autoimmunity, allergy or inflammatory conditions. Screening assays for identifying these agonists and antagonist compounds are also provided.

Abstract: The present invention provides binding molecules that specifically bind to GITR, e.g., human GITR (hGITR), on T cells and dendritic cells. Binding molecules of the invention are characterized by binding to hGITR with high affinity, in the presence of a stimulating agent, e.g., CD3, are agonistic, and abrogate the suppression of Teff cells by Treg cells. Various aspects of the invention relate to binding molecules, and pharmaceutical compositions thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such binding molecules. Methods of using a binding molecule of the invention to detect human GITR or to modulate human GITR activity, either in vitro or in vivo, are also encompassed by the invention.

Abstract: The receptor for VISTA is identified (VSIG8) as well as the use of this receptor in the identification or synthesis of agonist or antagonist compounds, preferably antibodies, polypeptides and fusion proteins which agonize or antagonize the effects of VSIG8 and/or VISTA and/or the VSIG8/VISTA binding interaction. These antagonists may be used to suppress VISTA's suppressive effects on T cell immunity, and more particularly used in the treatment of cancer, or infectious disease. These agonist compounds may be used to potentiate or enhance VISTA's suppressive effects on T cell immunity and thereby suppress T cell immunity, such as in the treatment of autoimmunity, allergy or inflammatory conditions. Screening assays for identifying these agonists and antagonist compounds are also provided.

Abstract: Disclosed herein are flexible display panels and bend detection circuits for flexible display panels where the bend detection circuit can be formed on a flexible substrate of the flexible display panel stack. The bend detection circuit including a number of sensor elements arranged to change an electric response to an applied electric signal based on an applied physical force. The bend detection circuits also including a bend sensing circuit arranged to measure a time delay of the number of sensor elements to the applied electric signal.

Abstract: Systems, methods, and circuitry for performing distributed speech processing are provided. In one example voice activation circuitry is configured to receive audio data detected by a gateway that is connected to a plurality of devices and recognize a key phrase based on the audio data. In response to recognizing the key phrase, the voice activation circuitry is configured to store the audio data in memory located in the gateway and provide the stored audio data to a selected device in the plurality of devices for speech processing.

Abstract: The present invention provides combination therapies that employ a GITR binding molecule in combination with one or more additional agents.

Abstract: The present invention provides binding molecules that specifically bind to GITR, e.g., human GITR (hGITR), on T cells and dendritic cells. Binding molecules of the invention are characterized by binding to hGITR with high affinity, in the presence of a stimulating agent, e.g., CD3, are agonistic, and abrogate the suppression of Teff cells by Treg cells. Various aspects of the invention relate to binding molecules, and pharmaceutical compositions thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such binding molecules. Methods of using a binding molecule of the invention to detect human GITR or to modulate human GITR activity, either in vitro or in vivo, are also encompassed by the invention.

Abstract: The present invention provides binding molecules that specifically bind to GITR, e.g., human GITR (hGITR), on T cells and dendritic cells. Binding molecules of the invention are characterized by binding to hGITR with high affinity, in the presence of a stimulating agent, e.g., CD3, are agonistic, and abrogate the suppression of Teff cells by Treg cells. Various aspects of the invention relate to binding molecules, and pharmaceutical compositions thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such binding molecules. Methods of using a binding molecule of the invention to detect human GITR or to modulate human GITR activity, either in vitro or in vivo, are also encompassed by the invention.