Patents by Inventor Michael Roy

Michael Roy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240108654
    Abstract: Provided herein are methods, compositions and uses involving T cell therapies, such as adoptive T cell therapy, and an inhibitor of a Diacylglycerol kinase (DGK). The provided methods, compositions and uses include those involving the administration or use of one or more DGK inhibitors (DGKi) in a combination therapy with a T cell therapy, such as a genetically engineered T cell therapy involving cells engineered with a recombinant receptor, such as chimeric antigen receptor (CAR) or T cell receptor (TCR).
    Type: Application
    Filed: March 2, 2022
    Publication date: April 4, 2024
    Applicant: Juno Therapeutics, Inc.
    Inventors: David G. KUGLER, Jim QIN, Alison MAIER, Richard OLSON, Michael WICHROSKI, Upender VELAPARTHI, Chetan Padmakar DARNE, Bireshwar DASGUPTA, Denise Christine GRUNENFELDER, Jayakumar Sankara WARRIER, Hasibur RAHAMAN, Prasada Rao JALAGAM, Saumya ROY, Pallavur SIVAKUMAR
  • Publication number: 20240108597
    Abstract: A composition, workout/exercise supplement, treatment method for conditions associated with vasoconstriction, and method of extracting galloylated procyanidins. The composition includes galloylated procyanidins having a preponderance of (?)-epicatechins. The treatment methods include administering a therapeutically effective amount of galloylated procyanidins having a preponderance of (?)-epicatechins. The extraction methods include isolating galloylated procyanidins having a preponderance of (?)-epicatechins from a sample that contains polyphenols, catechins, epicatechins, and galloylated epicatechins.
    Type: Application
    Filed: August 9, 2023
    Publication date: April 4, 2024
    Applicants: UNIVERSITY OF SOUTH FLORIDA, ENCORE IP MANAGEMENT, LLC
    Inventors: Michael Louis Sperduti, Matthew Cleary Nickerson, Jimmy Roy Huddleston, Leigh Anthony West
  • Patent number: 11946929
    Abstract: The invention generally relates to performing sandwich assays in droplets. In certain embodiments, the invention provides methods for detecting a target analyte that involve forming a compartmentalized portion of fluid including a portion of a sample suspected of containing a target analyte and a sample identifier, a first binding agent having a target identifier, and a second binding agent specific to the target analyte under conditions that produce a complex of the first and second binding agents with the target analyte, separating the complexes, and detecting the complexes, thereby detecting the target analyte.
    Type: Grant
    Filed: July 18, 2023
    Date of Patent: April 2, 2024
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Michael L. Samuels, Darren Roy Link
  • Publication number: 20240105081
    Abstract: A system and method are provided for utilizing a device positioned at or near a signage plate to provide non-visual assistance in approaching the signage plate's location when activated by a digital signal. A venue might improve accessibility by installing the invented device next to or even behind one or more restroom signs. A visitor using this accessibility feature might utilize a fob provided by the venue or a personal device such as a smartphone with a compatible app, such that the visitor can press a button and activate the invented device to generate a non-visual cue to assist the visitor in locating the device and associated sign, such as emitting an audio sound. The fob or phone might further provide additional guidance, such as emitting the same sound as the sign device so that the visitor knows what sound to listen for, or providing additional information.
    Type: Application
    Filed: September 26, 2022
    Publication date: March 28, 2024
    Applicant: AUDIBLE BRAILLE TECHNOLOGIES, LLC
    Inventors: MICHAEL ROY CONOVER, ANTONIO SABAREZ, II
  • Patent number: 11941021
    Abstract: Methods, systems, and computer-readable storage media for automatic creation of distributed ledger networks. A request to deploy a distributed ledger network is received by an automation framework. The request comprising a configuration file and is associated with a platform type for one or more platforms for deployment of the distributed ledger network. Configuration prerequisites are determined for performing installations of software components on the one or more platforms. In response to installing the software components, the software components are configured and executed to set up an environment for deploying the distributed ledger network by creating a build folder, copying the configuration file and key files for accessing a source code repository into the build folder, and updating the configuration file according to criteria associated with the platform type.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: March 26, 2024
    Assignee: Accenture Global Solutions Limited
    Inventors: Michael W. Klein, Manuel Merino, Pramodsing Bijani, Mahesh Krishna Bandkar, Mufaddal Moazam Kantawala, Anand Parulkar, Sownak Roy, Ankur A. Banerjee, Peter Bidewell
  • Patent number: 11940621
    Abstract: An apparatus comprises: a first integrated circuit comprising: a plurality of sets of optical waveguides, each set of optical waveguides including a plurality of optical waveguide segments, and a plurality of optical emitter elements arranged over a first surface of the first integrated circuit, each optical emitter element coupled to a distal end of one of the optical waveguide segments; and a second integrated circuit comprising: a plurality of optical phase shifters that each provide a phase-shifted optical wave that is coupled to the first integrated circuit from a first edge surface of the second integrated circuit. The first edge surface of the second integrated circuit is in proximity to a row of proximal ends of the optical waveguide segments of a first set of the plurality of sets of optical waveguides.
    Type: Grant
    Filed: September 2, 2021
    Date of Patent: March 26, 2024
    Assignee: Analog Photonics LLC
    Inventors: Michael Robert Watts, Ehsan Shah Hosseini, Benjamin Roy Moss, Christopher Vincent Poulton
  • Patent number: 11938191
    Abstract: Described herein are block copolymers, and methods of making and utilizing such copolymers. The described block copolymers are disruptive of a cellular membrane, including an extracellular membrane, an intracellular membrane, a vesicle, an organelle, an endosome, a liposome, or a red blood cell. Preferably, in certain instances, the block copolymer disrupts the membrane and enters the intracellular environment. In specific examples, the block copolymer is endosomolytic and capable of delivering an oligonucleotide (e.g., an mRNA) to a cell. Compositions comprising a block copolymer and an oligonucleotide (e.g., an mRNA) are also disclosed.
    Type: Grant
    Filed: May 1, 2020
    Date of Patent: March 26, 2024
    Assignee: GENEVANT SCIENCES GMBH
    Inventors: Sean D. Monahan, Michael S. Declue, Pierrot Harvie, Russell N. Johnson, Amber E. Paschal, Mary G. Prieve, Debashish Roy, Charbel Diab, Michael E. Houston, Jr., Anna Galperin, Maher Qabar
  • Publication number: 20240093124
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: April 17, 2023
    Publication date: March 21, 2024
    Inventors: Joshua Roy Basler, Michael Stoner, James T. Kellis, Jr., Adam Garske, David Marquez, Katherine Augustyn, Priyanka Chandrasekaran, Miles Christopher Scotcher, Lilia Maria Babe, Richard R. Bott, David A. Estell, Gudrun Vogtentanz, Sina Pricelius, Jian Yao
  • Patent number: 11919771
    Abstract: High quality, catalyst-free boron nitride nanotubes (BNNTs) that are long, flexible, have few wall molecules and few defects in the crystalline structure, can be efficiently produced by a process driven primarily by Direct Induction. Secondary Direct Induction coils, Direct Current heaters, lasers, and electric arcs can provide additional heating to tailor the processes and enhance the quality of the BNNTs while reducing impurities. Heating the initial boron feed stock to temperatures causing it to act as an electrical conductor can be achieved by including refractory metals in the initial boron feed stock, and providing additional heat via lasers or electric arcs. Direct Induction processes may be energy efficient and sustainable for indefinite period of time. Careful heat and gas flow profile management may be used to enhance production of high quality BNNT at significant production rates.
    Type: Grant
    Filed: October 7, 2021
    Date of Patent: March 5, 2024
    Assignee: BNNT, LLC
    Inventors: Michael W. Smith, Kevin C. Jordan, Jonathan C. Stevens, R. Roy Whitney
  • Publication number: 20240067600
    Abstract: The present technology relates to compounds of any one of Formula I, II, IIa, III, IV, and/or V as described herein and their tautomers and/or pharmaceutically acceptable salts, compositions, and methods of uses thereof.
    Type: Application
    Filed: March 16, 2023
    Publication date: February 29, 2024
    Applicants: UNIVERSITY OF KANSAS, Oregon Health & Science University
    Inventors: Sudeshna ROY, Paolo BERNARDI, Michael FORTE, Frank SCHOENEN, Justina SILEIKYTE
  • Publication number: 20240066797
    Abstract: A 3D printing apparatus and method includes a piezo actuator that reciprocates a tappet. The reciprocation of the tappet generates pressure within a chamber filled with molten print material. The generated pressure causes the molten print material to be extruded through a nozzle coupled to the chamber. The piezo actuator is controlled to switchably provide continuous extrusion of print material or extrusion of discrete droplets of print material.
    Type: Application
    Filed: August 23, 2022
    Publication date: February 29, 2024
    Inventors: Maxim Seleznev, Joseph Roy-Mayhew, Benjamin Gallup, Yuwei Li, Michael Imburgia
  • Publication number: 20240003097
    Abstract: A maintenance vehicle for an attraction system includes a maintenance component configured to output a material onto a path of a pathway system of the attraction system, a guide engager configured to capture a projection of the pathway system, the projection being separate from the path, and a set of wheels configured to move the maintenance vehicle along the pathway system while the guide engager maintains capture of the projection to move the maintenance component along the path.
    Type: Application
    Filed: June 29, 2022
    Publication date: January 4, 2024
    Inventors: Michael Roy Kiddoo, Rebecca Barbara Dean
  • Patent number: 11831237
    Abstract: A power supply includes a power factor correction (PFC) circuit, a PFC bypass circuit, and a decision circuit. The PFC circuit is configured to receive an input current from a power source and, when enabled, reduce current harmonics in the input current by shaping an input sinusoidal current waveform to match a phase and shape of a sinusoidal input voltage waveform. The PFC bypass circuit is configured to bypass the PFC circuit when the PFC circuit is disabled. The decision circuit includes a detection circuit configured to detect an output load of the power supply and is configured to output a PFC enable command based at least in part on the detected output load being greater than or equal to a threshold value and a determination that an input voltage of the power source is greater than or equal to a threshold value.
    Type: Grant
    Filed: March 23, 2022
    Date of Patent: November 28, 2023
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Chee Kiong Fong, Michael Roy Volkman, Geoffrey Jason Shew, Suet Fong Tin, Marshall T Depue
  • Publication number: 20230287490
    Abstract: The disclosure provides compositions and methods for assaying the function or properties of a plurality of polypeptides. In particular, the disclosure provides methods for high-throughput characterization of large population of polypeptides. Each polypeptide is displayed on a solid surface, such as a bead, where the solid surface also displays a nucleic acid that encodes the polypeptide. For example, each polypeptide may be covalently linked to a nucleic acid that encodes the polypeptide. In preferred embodiments, the polypeptide and nucleic acid are assayed in parallel, and with the same instrument.
    Type: Application
    Filed: July 27, 2021
    Publication date: September 14, 2023
    Inventors: Michael Roy GOTRIK, Curtis James LAYTON, Pavanapuresan Pushpagiri VAIDYANATHAN
  • Publication number: 20230279595
    Abstract: A sewing machine for sewing a stitch into an article is provided. The sewing machine includes a support structure, a first head and a second head. The first head is coupled to the support structure and includes a coupler contained within a second actuator assembly and 360° rotatable relative to the support structure and a first stitching element rotatable with the coupler and translatable via a first actuator assembly relative to the coupler. The second head is coupled to the support structure and includes a coupler contained within the second actuator assembly and 360° degree rotatable relative to the support structure and a second stitching element rotatable with the coupler via the first actuator assembly.
    Type: Application
    Filed: February 10, 2023
    Publication date: September 7, 2023
    Inventors: Darren Wendel, Joseph Cox, Ramez Habhab, Edward Wenzel, Nicholas Hallstedt, Michael Roy
  • Publication number: 20230188031
    Abstract: A power supply includes a power factor correction (PFC) circuit, a PFC bypass circuit, and a decision circuit. The PFC circuit is configured to receive an input current from a power source and, when enabled, reduce current harmonics in the input current by shaping an input sinusoidal current waveform to match a phase and shape of a sinusoidal input voltage waveform. The PFC bypass circuit is configured to bypass the PFC circuit when the PFC circuit is disabled. The decision circuit includes a detection circuit configured to detect an output load of the power supply and is configured to output a PFC enable command based at least in part on the detected output load being greater than or equal to a threshold value and a determination that an input voltage of the power source is greater than or equal to a threshold value.
    Type: Application
    Filed: March 23, 2022
    Publication date: June 15, 2023
    Applicant: Microsoft Technology Licensing, LLC
    Inventors: Chee Kiong FONG, Michael Roy VOLKMAN, Geoffrey Jason SHEW, Suet Fong TIN, Marshall T. DEPUE
  • Publication number: 20230132462
    Abstract: A deflector selectively connectable to a helmet is disclosed. The helmet has a helmet shell and a jaw shield defining at least one jaw aperture configured to permit air flow therethrough. The deflector has a deflector body and at least one connecting protrusion receivable in the at least one jaw aperture to restrict air flow. A helmet having the deflector is disclosed. A helmet having a helmet shell, left and right holders having first and second connectors and a peak adjustable between first and second configurations is disclosed. The peak has left and right connecting portions, each having third and fourth connectors. The first connectors are rotationally connected to the third connectors. The second connectors are selectively connected to the fourth connectors in one of at least two positions. The second connectors are at a first position in the first configuration, and at a second position in the second configuration.
    Type: Application
    Filed: October 31, 2022
    Publication date: May 4, 2023
    Inventors: Michael ROY, Oussama YAHYAOUI
  • Patent number: 11620658
    Abstract: A system and method for hidden security feature detection, analysis and authentication using a smart device is disclosed. The smart device can detect and analyze hidden security features using the camera capability of the smart device to capture a digital image, and then analyze and authenticate that image using a security service including a database of security feature data, processing rules, and other information. The security service can support a variety of smart devices and security features. The smart device includes a security-specific autofocus function that allows the smart device to be positioned within a range of distances and angles from a target document that includes hidden/covert security feature(s). The smart device can display an enhanced image showing the hidden security feature(s) and/or report if the security feature is valid or invalid, along with related information, via beeps, vibration, display, text messaging, or other reporting capabilities.
    Type: Grant
    Filed: February 4, 2020
    Date of Patent: April 4, 2023
    Assignee: PROOF AUTHENTICATION CORPORATION
    Inventors: Michael Caton, Michael Roy, David Wicker, Nicole Acton, Jaeson Caulley
  • Publication number: 20230043117
    Abstract: A power supply unit (PSU) configured to provide electrical power to an electronic device. The PSU may include a PSU control circuit configured to, via a power meter, detect that electrical power conveyed to the electronic device is above a timer starting threshold. In a first charging mode with a first predetermined charging duration, the PSU control circuit may control the PSU to convey electrical power to the electronic device with a first power ceiling. Subsequently to the first predetermined charging duration elapsing, in a second charging mode with a second predetermined charging duration, the PSU control circuit may control the PSU to convey electrical power to the electronic device with a second power ceiling that is lower than the first power ceiling. Subsequently to the second predetermined charging duration elapsing, the PSU control circuit may control the PSU to return to the first charging mode.
    Type: Application
    Filed: November 2, 2021
    Publication date: February 9, 2023
    Applicant: Microsoft Technology Licensing, LLC
    Inventors: Chee Kiong FONG, Michael Roy VOLKMAN, Suet Fong TIN, Geoffrey Jason SHEW, Edward Charles GIAIMO, III, Cindy-Kay FORSYTH-MARTINEZ
  • Patent number: 11554403
    Abstract: In order to provide a balanced bent lip disc, the applicant routinely had issues with rippling at an outer circumference edge of the lip. Due to the geometries involved in a 3½ inch disc bent to provide an outer lip of ½ inch at 45 degrees, 0.1145 of excess circumference is created thereby providing a ripple effect. The applicant discovered that simultaneously embossing the lip while bending the lip could reduce this rippling effect (and the outer circumference at the edge) by at least 75 if not 90 or 95% of a non-embossed lip bent in the same manner.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: January 17, 2023
    Assignee: Trailblazer Attachments LLC
    Inventors: William Robert Thompson, Michael Roy Turner