Patents by Inventor Michael Ruane

Michael Ruane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8729134
    Abstract: Compounds of formula (I): wherein R1 and R4 are OR7, R2 and R3 are H or OR7, with the proviso that when R2 is OR7 then R3 is H, and when R3 is OR7 then R2 is H; R5 and R6 are independently H, OH, or OR7 with the proviso that when R5 is OH, R6 is not OH; R7 is alkyl, aryl or arylalkyl; the drawing “” represents either a single or a double bond; or pharmaceutically acceptable salt(s) or prodrug(s) thereof. These compounds are useful of treatment, prophylaxis, amelioration, or defense against and/or prevention of hormonal dependent conditions, cancer, and diseases and conditions associated with oxidant stress.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: May 20, 2014
    Assignee: Heartlink Limited
    Inventors: Michael Ruane, Tracey-Ann Dickens
  • Publication number: 20110263721
    Abstract: Compounds of formula (I): wherein R1 and R4 are OR7, R2 and R3 are H or OR7, with the proviso that when R2 is OR7 then R3 is H, and when R3 is OR7 then R2 is H; R5 and R6 are independently H, OH, or OR7 with the proviso that when R5 is OH, R6 is not OH; R7 is alkyl, aryl or arylalkyl; the drawing “” represents either a single or a double bond; or pharmaceutically acceptable salt(s) or prodrug(s) thereof. These compounds are useful of treatment, prophylaxis, amelioration, or defense against and/or prevention of hormonal dependent conditions, cancer, and diseases and conditions associated with oxidant stress.
    Type: Application
    Filed: November 13, 2009
    Publication date: October 27, 2011
    Applicant: HEARTLINK LIMITED
    Inventors: Michael Ruane, Tracey-Anne Dickens
  • Patent number: 7348152
    Abstract: An isolated RBP with at least one of the following characteristics: a) a molecular weight of approximately 65-70 kDa and more preferably 66-69 kDa; b) a pI of greater than 10 or less than 3; c) a dissociation constant of approximately 1.5×10?6 when bound to the rhamnose moiety of solamargine; d) adapted to bind to a rhamnose affinity column prepared according to example 1 and under the conditions set out therein; e) adapted to be eluted from the column in example 1 with a 100 mM rhamnose solution; f) insoluble in aqueous solution; and g) soluble in highly denaturing buffers containing greater that approximately 2% surfactant.
    Type: Grant
    Filed: March 3, 2005
    Date of Patent: March 25, 2008
    Assignee: Solbec Pharmaceutical Limited
    Inventors: Richard J. Lipscombe, Stephen John Carthr, Michael Ruane
  • Publication number: 20060182659
    Abstract: An assay system having a channel bounded by first and second reflective surfaces adapted to accommodate a fluid material therebetween and defining a plurality of regions in an array between those surfaces with each region defining a resonant cavity and adapted to receive a capturing material on a surface thereof whereby a source of radiation illuminates each region to provide a standing wave of radiation of within the cavity indicative of binding of said capturing agent to material under investigation, a binding thereof being detected in response to radiation from each cavity indicative of a change in the standing wave pattern.
    Type: Application
    Filed: March 19, 2004
    Publication date: August 17, 2006
    Inventors: M Unlu, David Bergstein, Michael Ruane, Bennett Goldberg
  • Patent number: 6930171
    Abstract: An isolated RBP with at least one of the following characteristics: a) a molecular weight of approximately 65-70 kDa and more preferably 66-69 kDa; b) a pl of greater than 10 or less than 3; c) a dissociation constant of approximately 1.5×10?6 when bound to the rhamnose moiety of solamargine; d) adapted to bind to a rhamnose affinity column prepared according to example 1 and under the conditions set out therein; e) adapted to be eluted from the column in example 1 with a 100 mM rhamnose solution; f) insoluble in aqueous solution; and g) soluble in highly denaturing buffers containing greater that approximately 2% surfactant.
    Type: Grant
    Filed: February 7, 2003
    Date of Patent: August 16, 2005
    Assignee: Solbec Pharmaceuticals Limited
    Inventors: Richard J. Lipscombe, Stephen John Carter, Michael Ruane
  • Publication number: 20050170421
    Abstract: An isolated RBP with at least one of the following characteristics: a) a molecular weight of approximately 65-70 kDa and more preferably 66-69 kDa; b) a pI of greater than 10 or less than 3; c) a dissociation constant of approximately 1.5×10?6 when bound to the rhamnose moiety of solamargine; d) adapted to bind to a rhamnose affinity column prepared according to example 1 and under the conditions set out therein; e) adapted to be eluted from the column in example 1 with a 100 mM rhamnose solution; f) insoluble in aqueous solution; and g) soluble in highly denaturing buffers containing greater that approximately 2% surfactant.
    Type: Application
    Filed: March 3, 2005
    Publication date: August 4, 2005
    Applicant: Solbec Pharmaceuticals Limited
    Inventors: Richard Lipscombe, Stephen Carter, Michael Ruane
  • Publication number: 20040030104
    Abstract: An isolated RBP with at least one of the following characteristics:
    Type: Application
    Filed: February 7, 2003
    Publication date: February 12, 2004
    Applicant: SOLBEC PHARMACEUTICALS LIMITED
    Inventors: Richard J. Lipscombe, Stephen John Carter, Michael Ruane
  • Patent number: 5108185
    Abstract: An apparatus for measuring the reflectivity of magnetooptic materials where the complex reflection coefficients of absorbing anisotropic media are determined. Amorphous rare-earth transition metal alloys exhibiting polar Kerr effect are analyzed for use as storage media in erasable optical storage systems.
    Type: Grant
    Filed: June 12, 1989
    Date of Patent: April 28, 1992
    Assignee: Boston University
    Inventors: Masud Mansuripur, Michael Ruane, Robert Rosenvold
  • Patent number: 4838695
    Abstract: An apparatus for measuring the reflectivity of magnetooptic materials where the complex reflection coefficients of absorbing anisotropic media are determined. Amorphous rare-earth transition metal alloys exhibiting polar Kerr effect are analyzed for use as storage media in erasable optical storage systems.
    Type: Grant
    Filed: June 12, 1987
    Date of Patent: June 13, 1989
    Assignee: Boston University
    Inventors: Masud Mansuripur, Michael Ruane, Robert Rosenvold