Abstract: The invention relates to compounds of formula (I): and related aspects.

Abstract: A medical apparatus for widening a stenosis in the airway of a patient which includes a central hollow core, an inflatable outer balloon, and at least one inner balloon inside the outer balloon. The apparatus also can include a flexible support member mounted on the external surface of the outer balloon with at least one microsurgical blade. The outer balloon can be dumbbell-shaped to keep the balloon in position over the stenosis when the balloon is inflated. The hollow core allows the patient to be ventilated during the procedure, the inner balloon(s) allow higher dilation pressures to be generated from inside the outer balloon, and the blade can form an effective cutting edge upon inflation of the outer balloon.

Abstract: A medical apparatus for widening a stenosis in the airway of a patient which includes a central hollow core, an inflatable outer balloon, and at least one inner balloon inside the outer balloon. The apparatus also can include a flexible support member mounted on the external surface of the outer balloon with at least one microsurgical blade. The outer balloon can be dumbbell-shaped to keep the balloon in position over the stenosis when the balloon is inflated. The hollow core allows the patient to be ventilated during the procedure, the inner balloon(s) allow higher dilation pressures to be generated from inside the outer balloon, and the blade can form an effective cutting edge upon inflation of the outer balloon.

Abstract: An adjustable collar and retainer for a nasal or oral endotracheal tube are disclosed. The collar comprises a smooth first surface for contacting the skin of the patient, a support section attached to the first surface, and a band attached to the support section comprising flexible domes that compress against the tube and grip it when the collar is secured around the tube. The retainer comprises the adjustable collar and lateral extensions from the collar for securing the collar to the head of the patient. The retainer optionally further comprises at least one strap attached to the lateral extensions for securing the collar to the head of the patient.

Abstract: Disclosed is a pressure vessel comprising a pressurized chamber; an overflow chute having an inlet open to an upper level of the chamber, a chute passage extending from the upper level to a lower level, and a chute discharge; wherein the chute passage has a bend to defect a flow in the chute passage before the flow exits the discharge.