Abstract: A system and method for sending encrypted messages to a distribution list that facilitates the sending of such messages only to individuals or other entities associated with the distribution list that will be able to read the message.

Abstract: A system and method of selecting messaging settings on a messaging client are provided. A data store configured to operate in conjunction with the messaging client stores records comprising messaging settings or characteristics for previously received and/or sent messages. The messaging client is configured to send outgoing messages, each of the messages having message characteristics, to determine whether a record for an addressed recipient of an outgoing message exists in the data store, and to select messaging settings to control the message characteristics of the outgoing message based on the record where a record exists.

Abstract: Ghrelin O-acyltransferase (GOAT) is inhibited with designed small molecules. Methods comprise contacting the GOAT with an inhibitor and detecting a resultant inhibition.

Abstract: A method and system for Certificate management and transfer between messaging clients are disclosed. When communications are established between a first messaging client and a second messaging client, one or more Certificates stored on the first messaging client may be selected and transferred to the second messaging client. Messaging clients may thereby share Certificates. Certificate management functions such as Certificate deletions, Certificate updates and Certificate status checks may also be provided.

Abstract: Systems and methods for establishing a security-related mode of operation for computing devices. A security-related mode of operation is established through security mode configuration data. The security mode configuration data specifies the proper security mode or modes for operation of the computing devices.

Abstract: A device and method for generating user notifications associated with tasks that are pending completion on a mobile device. When additional input is required from a user of the mobile device to complete performance of a task and is not being received from the user within a predefined time period, at least one form of user notification is generated. The particular form or forms of user notification are defined by a user profile associated with the user. User notifications may comprise visual, audible, and/or vibratory alerts, and different forms of these user notifications may be generated in a sequence. The volume of audible alerts or the period between periodic user notifications may vary over time.

Abstract: Disclosed are methods and compositions for the identification of inhibitors of farnesyl protein transferases, enzymes involved in the farnesylation of various cellular proteins, including cancer related ras proteins such as p21ras. One farnesyl protein transferase which is disclosed herein exhibits a molecular weight of between about 70,000 and about 100,000 upon gel exclusion chromatography. The enzyme appears to comprise one or two subunits of approximately 50 kDa each. Methods are disclosed for assay and purification of the enzyme, as well as procedures for using the purified enzyme in screening protocols for the identification of possible anticancer agents which inhibit the enzyme and thereby prevent expression of proteins such as p21ras. Also disclosed is a families of compounds which act either as false substrates for the enzyme or as pure inhibitors and can therefore be employed for inhibition of the enzyme.

Abstract: Embodiments of a system and method for providing additional security for data being transmitted across a wireless connection that has been established using a known wireless protocol (e.g. Bluetooth) are described. An encryption key is exchanged between a computing device (e.g. a mobile device) and a wireless peripheral device (e.g. a keyboard, a printer). In exemplary embodiments, the encryption key is generated at one of the two devices. Data associated with the encryption key is output at the one device, which can be input by the user at the other device. The encryption key is then recovered at the other device from the input, thereby completing the key exchange. The encryption key can then be used to encrypt and decrypt data transmitted over the established wireless connection, providing additional security.

Abstract: A system and method for processing attachments to messages sent to a mobile device is described herein. Embodiments described herein apply to encrypted messages comprising multiple message parts, in which different encryption keys (e.g. session keys) have been used to encrypt the different message parts. In at least one example embodiment, the encrypted session keys for every message content part comprising an attachment is received at the mobile device. In one embodiment, all of the encrypted session keys are stored together in a main message header. The mobile device may then decrypt the encrypted session key associated with a user requested attachment, and transmits the decrypted session key to one or more remote servers in an attachment request for use in decrypting the requested attachment. Data associated with the requested attachment, in decrypted form, is returned to the mobile device.

Abstract: Systems and methods for processing messages within a wireless communications system are disclosed. A server within the wireless communications system maintains a list of certificates contained in devices that use the server. The server synchronizes or updates the list of certificates based on information contained in message to and from the device. By providing a server with certificates associated with devices that use the server, and providing a system and method for synchronizing the certificates between the device and server, the server can implement powerful features that will improve the efficiency, speed and user satisfaction of the devices.

Abstract: A method and apparatus for providing intelligent error messaging is disclosed wherein a user of a mobile communications device is provided with descriptive error messaging information to assist the user in overcoming errors associated with the processing of electronic messages and data.

Abstract: A wireless communication device (and its related method of operation) includes, if invoked, password protected access to data stored therewithin and/or to normal device operations and further includes duress password checking logic that automatically causes a duress message to be sent if a duress password has been entered. The duress message is preferably sent without maintaining any user accessible indication of such sending. It is also preferred that the password checking logic automatically cause an end-of-duress message to be sent if a normal password is entered after a duress password has been entered. A plurality of different duress passwords may be entered into a duress password portion of data memory in the device.

Abstract: Systems and methods for displaying messages to a user, the messages having different levels of security, are provided herein. One method of displaying to a user messages having different levels of security includes receiving a message over a network includes examining an attribute of the message to determine a security-related level associated with the message. A visual indication for display to a device user is generated by the device. Such visual indication is indicative of the determined security-related level, and is configured to be visible during scrolling through a majority of the message text.

Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a SCAP gene (Human SCAP gene), comprising an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of a SCAP gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by Human SCAP expression and the expression of a SCAP gene using the pharmaceutical composition; and methods for inhibiting the expression of a SCAP gene in a cell.

Abstract: A method for preventing a recipient of an electronically transmitted message from taking at least one action in relation to the message is disclosed. The message has at least two parts with one of the parts having a higher level of security than the other part. The method includes the step of extracting information from the message. The information indicates that the higher level security part is not permitted to have the action taken on it while the other part is so permitted. The method also includes the step of preventing the higher level security part from having the action taken on it in reaction to said recipient making an offending request.

Abstract: Systems and methods for handling restoration operations for a mobile device. A mobile device receives a kill pill command, wherein the command causes some or all data on the mobile device to be wiped. An indicator is stored to indicate that the kill pill command was sent to the mobile device. The indicator is used to determine whether a program should be wiped from the mobile device.

Abstract: A method for processing security communication protocol compliant signed receipts at a mobile communication device linked to a host system is provided. The host system receives an email message linked to a digital signature, and a signed receipt. The host system redirects the signed receipt to the mobile communication device. The host system determines if the email message is available at the mobile communication device, and if not, the host system retrieves the email message and redirects the email message to the mobile communication device. The mobile communication device can then verify the signed receipt based on the email message. Optionally, rather than the email message, the host system retrieves and/or recalculates data elements associated with the email message and required to verify the signed receipt, and redirects these data elements to the mobile communication device.

Abstract: A hand-held electronic device with a keyboard, thumbwheel, display and associated software is optimized for use of the device with the thumbs. The associated software has a plurality of features to optimize efficient use of the limited keyboard space and encourage the use of the device by thumb-based data entry through the thumbwheel and/or through a combination of minimal number of keystrokes. Software features include international character scrolling, and auto-capitalization. The keys on the device keyboard are optimally shaped and configured for thumb-based input. In addition, the thumbwheel is inclined between the front and a side edge of the device so as to be reachable by either the thumb or index finger of the user's hand at the side edge of the device.

Abstract: Systems and methods for processing messages within a wireless communications system are disclosed. A server within the wireless communications system maintains a list of certificates contained in devices that use the server. The server synchronizes or updates the list of certificates based on information contained in message to and from the device. By providing a server with certificates associated with devices that use the server, and providing a system and method for synchronizing the certificates between the device and server, the server can implement powerful features that will improve the efficiency, speed and user satisfaction of the devices. The exemplary embodiments also enable advantageous bandwidth savings by preventing transmission of certificates unnecessarily.

Abstract: Various embodiments are described for providing password approval on a device. The password approval includes getting the user password, generating at least one symbolically equivalent password and then comparing the at least one symbolically equivalent password with at least one specified forbidden password. The user password is disapproved if one of the symbolically equivalent passwords corresponds to the at least one forbidden password.