Patents by Inventor Michael S. Bultman

Michael S. Bultman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing halogenated azaindole compounds using boroxine
    Patent number: 9908882
    Abstract: A process for preparing halogenated azaindole compounds makes use of stable reagents including a brominating reagent, a boroxine and a sulfonic anhydride to enhance the selectivity and yield of the final product. In addition, the process is associated with various other advantages, including the ability to recycle reagents, cost reduction, and improved manufacturability.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: March 6, 2018
    Assignee: ViiV HEALTHCARE UK (NO.4) LIMITED
    Inventors: Michael S. Bultman, Benjamin Cohen, Francisco Gonzalez-Bobes, Matthew R. Hickey
  • A PROCESS FOR PREPARING HALOGENATED AZAINDOLE COMPOUNDS USING PYBROP
    Publication number: 20170362262
    Abstract: A process for preparing halogenated azaindole compounds makes use of a brominating agent PyBroP, together with a dehydrating agent BSA to enhance the selectivity and improve the yield of the final product which is a piperazine prodrug useful as an antiviral.
    Type: Application
    Filed: December 17, 2015
    Publication date: December 21, 2017
    Inventors: Michael S. BULTMAN, Benjamin COHEN, Francisco GONZALEZ-BOBES, Matthew R. HICKEY
  • PROCESS FOR PREPARING HALOGENATED AZAINDOLE COMPOUNDS USING BOROXINE
    Publication number: 20170298064
    Abstract: A process for preparing halogenated azaindole compounds makes use of stable reagents including a brominating reagent, a boroxine and a sulfonic anhydride to enhance the selectivity and yield of the final product. In addition, the process is associated with various other advantages, including the ability to recycle reagents, cost reduction, and improved manufacturability.
    Type: Application
    Filed: December 17, 2015
    Publication date: October 19, 2017
    Inventors: Michael S. BULTMAN, Benjamin COHEN, Francisco GONZALEZ-BOBES, Matthew R. HICKEY
  • Methods for the preparation of HIV attachment inhibitor piperazine prodrug compound
    Patent number: 9403821
    Abstract: A method for making the compound is set forth utilizing the starting material
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: August 2, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Martin D. Eastgate, Michael S. Bultman, Ke Chen, Dayne Dustan Fanfair, Richard J. Fox, Thomas E. La Cruz, Boguslaw M. Mudryk, Christina Ann Risatti, James H. Simpson, Maxime C. Soumeillant, Jonathan Clive Tripp, Yi Xiao
  • Methods for the preparation of HIV attachment inhibitor piperazine prodrug compound
    Patent number: 9394322
    Abstract: A method for making the compound is set forth utilizing the starting material
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: July 19, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Martin D. Eastgate, Michael S. Bultman, Ke Chen, Dayne Dustan Fanfair, Richard J. Fox, Thomas E. La Cruz, Boguslaw M. Mudryk, Christina Ann Risatti, James H Simpson, Maxime C. Soumeillant, Jonathan Clive Tripp, Yi Xiao
  • Methods for the preparation of HIV attachment inhibitor piperazine prodrug compound
    Patent number: 9376458
    Abstract: A method for making the compound is set forth utilizing the starting material
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: June 28, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Martin D. Eastgate, Michael S. Bultman, Ke Chen, Dayne Dustan Fanfair, Richard J. Fox, Thomas E. La Cruz, Boguslaw M. Mudryk, Christina Ann Risatti, James H. Simpson, Maxime C. Soumeillant, Jonathan Clive Tripp, Yi Xiao
  • METHODS FOR THE PREPARATION OF HIV ATTACHMENT INHIBITOR PIPERAZINE PRODRUG COMPOUND
    Publication number: 20160152644
    Abstract: A method for making the compound is set forth utilizing the starting material
    Type: Application
    Filed: January 4, 2016
    Publication date: June 2, 2016
    Inventors: Martin D. Eastgate, Michael S. Bultman, Ke Chen, Dayne Dustan Fanfair, Richard J. Fox, Thomas E. La Cruz, Boguslaw M. Mudryk, Christina Ann Risatti, James H. Simpson, Maxime C. Soumeillant, Jonathan Clive Tripp, Yi Xiao
  • METHODS FOR THE PREPARATION OF HIV ATTACHMENT INHIBITOR PIPERAZINE PRODRUG COMPOUND
    Publication number: 20160108029
    Abstract: A method for making the compound is set forth utilizing the starting material
    Type: Application
    Filed: October 17, 2014
    Publication date: April 21, 2016
    Inventors: Martin D. Eastgate, Michael S. Bultman, Ke Chen, Dayne Dustan Fanfair, Richard J. Fox, Thomas E. La Cruz, Boguslaw M. Mudryk, Christina Ann Risatti, James H. Simpson, Maxime C. Soumeillant, Jonathan Clive Tripp, Yi Xiao
  • Methods for the Preparation of HIV attachment inhibitor piperazine prodrug compound
    Patent number: 9255113
    Abstract: A method for making the compound is set forth utilizing the starting material wherein R7?—H, alkyl, aryl, —SO2R, —C(O)OR, and —C(O)NR2; where R?—H, C1-C6 alkyl, -aryl, and —CH2Aryl.
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: February 9, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Martin D. Eastgate, Michael S. Bultman, Ke Chen, Dayne Dustan Fanfair, Richard J. Fox, Thomas E. La Cruz, Boguslaw M. Mudryk, Christina Ann Risatti, James H. Simpson, Maxime C. Soumeillant, Jonathan Clive Tripp, Yi Xiao
  • Methods for the preparation of HIV attachment inhibitor piperazine prodrug compound
    Patent number: 9249168
    Abstract: A method for making the compound is set forth utilizing the starting material
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: February 2, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Martin D. Eastgate, Michael S. Bultman, Ke Chen, Dayne Dustan Fanfair, Richard J. Fox, Thomas E. La Cruz, Boguslaw M. Mudryk, Christina Ann Risatti, James H. Simpson, Maxime C. Soumeillant, Jonathan Clive Tripp, Yi Xiao
  • Methods for the preparation of HIV attachment inhibitor piperazine prodrug compound
    Patent number: 9243010
    Abstract: A process for the preparation of the compound of Formula I is set forth utilizing the starting compound 1 and the acid chloride compound
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: January 26, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Martin D. Eastgate, Michael S. Bultman, Ke Chen, Dayne Dustan Fanfair, Richard J. Fox, Thomas E. La Cruz, Boguslaw M. Mudryk, Christina Ann Risatti, James H. Simpson, Maxime C. Soumeillant, Jonathan Clive Tripp, Yi Xiao
  • METHODS FOR THE PREPARATION OF HIV ATTACHMENT INHIBITOR PIPERAZINE PRODRUG COMPOUND
    Publication number: 20150038711
    Abstract: A method for making the compound is set forth utilizing the starting material
    Type: Application
    Filed: October 17, 2014
    Publication date: February 5, 2015
    Inventors: Martin D. Eastgate, Michael S. Bultman, Ke Chen, Dayne Dustan Fanfair, Richard J. Fox, Thomas E. La Cruz, Boguslaw M. Mudryk, Christina Ann Risatti, James H. Simpson, Maxime C. Soumeillant, Jonathan Clive Tripp, Yi Xiao
  • METHODS FOR THE PREPARATION OF HIV ATTACHMENT INHIBITOR PIPERAZINE PRODRUG COMPOUND
    Publication number: 20150038717
    Abstract: A method for making the compound is set forth utilizing the starting material
    Type: Application
    Filed: October 17, 2014
    Publication date: February 5, 2015
    Inventors: Martin D. Eastgate, Michael S. Bultman, Ke Chen, Dayne Dustan Fanfair, Richard J. Fox, Thomas E. La Cruz, Boguslaw M. Mudryk, Christina Ann Risatti, James H. Simpson, Maxime C. Soumeillant, Jonathan Clive Tripp, Yi Xiao
  • METHODS FOR THE PREPARATION OF HIV ATTACHMENT INHIBITOR PIPERAZINE PRODRUG COMPOUND
    Publication number: 20150038716
    Abstract: A method for making the compound is set forth utilizing the starting material
    Type: Application
    Filed: October 17, 2014
    Publication date: February 5, 2015
    Inventors: Martin D. Eastgate, Michael S. Bultman, Ke Chen, Dayne Dustan Fanfair, Richard J. Fox, Thomas E. La Cruz, Boguslaw M. Mudryk, Christina Ann Risatti, James H. Simpson, Maxime C. Soumeillant, Jonathan Clive Tripp, Yi Xiao
  • METHODS FOR THE PREPARATION OF HIV ATTACHMENT INHIBITOR PIPERAZINE PRODRUG COMPOUND
    Publication number: 20150038712
    Abstract: A method for making the compound is set forth utilizing the starting material
    Type: Application
    Filed: October 17, 2014
    Publication date: February 5, 2015
    Inventors: Martin D. Eastgate, Michael S. Bultman, Ke Chen, Dayne Dustan Fanfair, Richard J. Fox, Thomas E. La Cruz, Boguslaw M. Mudryk, Christina Ann Risatti, James H. Simpson, Maxime C. Soumeillant, Jonathan Clive Tripp, Yi Xiao
  • METHODS FOR THE PREPARATION OF HIV ATTACHMENT INHIBITOR PIPERAZINE PRODRUG COMPOUND
    Publication number: 20150038709
    Abstract: A method for making the compound is set forth utilizing the starting material
    Type: Application
    Filed: October 17, 2014
    Publication date: February 5, 2015
    Inventors: Martin D. Eastgate, Michael S. Bultman, Ke Chen, Dayne Dustan Fanfair, Richard J. Fox, Thomas E. La Cruz, Boguslaw M. Mudryk, Christina Ann Risatti, James H. Simpson, Maxime C. Soumeillant, Jonathan Clive Tripp, Yi Xiao
  • METHODS FOR THE PREPARATION OF HIV ATTACHMENT INHIBITOR PIPERAZINE PRODRUG COMPOUND
    Publication number: 20150038710
    Abstract: A method for making the compound is set forth utilizing the starting material
    Type: Application
    Filed: October 17, 2014
    Publication date: February 5, 2015
    Inventors: Martin D. Eastgate, Michael S. Bultman, Ke Chen, Dayne Dustan Fanfair, Richard J. Fox, Thomas E. La Cruz, Boguslaw M. Mudryk, Christina Ann Risatti, James H. Simpson, Maxime C. Soumeillant, Jonathan Clive Tripp, Yi Xiao
  • Methods for the preparation of HIV attachment inhibitor piperazine prodrug compound
    Patent number: 8889869
    Abstract: A method for making the compound is set forth utilizing the starting material
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: November 18, 2014
    Assignee: Bristol-Myers Squibb Company
    Inventors: Martin D. Eastgate, Michael S. Bultman, Ke Chen, Dayne Dustan Fanfair, Richard J. Fox, Thomas E. La Cruz, Boguslaw M. Mudryk, Christina Ann Risatti, James H. Simpson, Maxime C. Soumeillant, Jonathan Clive Tripp, Yi Xiao