Patents by Inventor Michael S. DeMott

Michael S. DeMott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of quantifying RNA and DNA variants through sequencing employing phosphorothioates
    Patent number: 11802311
    Abstract: This disclosure provides methods and compositions for analyzing nucleic acids such as DNA and RNA, and including determination of absolute numbers of such nucleic acids and/or detection and localization of lesions or other modifications on such nucleic acids.
    Type: Grant
    Filed: January 15, 2019
    Date of Patent: October 31, 2023
    Assignee: Massachusetts Institute of Technology
    Inventors: Bo Cao, Peter C. Dedon, Jennifer F. Hu, Michael S. DeMott
  • METHODS OF QUANTIFYING RNA AND DNA VARIANTS THROUGH SEQUENCING EMPLOYING PHOSPHOROTHIOATES
    Publication number: 20190284624
    Abstract: This disclosure provides methods and compositions for analyzing nucleic acids such as DNA and RNA, and including determination of absolute numbers of such nucleic acids and/or detection and localization of lesions or other modifications on such nucleic acids.
    Type: Application
    Filed: January 15, 2019
    Publication date: September 19, 2019
    Applicant: Massachusetts Institute of Technology
    Inventors: Bo Cao, Peter C. Dedon, Jennifer F. Hu, Michael S. DeMott
  • ENZYMATIC PHOSPHOROTHIOATION OF DNA OR RNA
    Publication number: 20140308711
    Abstract: This invention relates to methods, compositions, and kits for enzymatic phosphorothioation of the sugar-phosphate backbone of nucleic acids. The invention allows for phosphorothioation of pre-existing nucleic acids.
    Type: Application
    Filed: March 13, 2014
    Publication date: October 16, 2014
    Applicants: Massachusetts Institute of Technology, Wuhan University, Shanghai Jiaotong University
    Inventors: Peter C. Dedon, Delin You, Bo Cao, Ramesh Babu Indrakanti, Michael S. DeMott, Lianrong Wang, Zixin Deng, Xiufen Zhou