Patents by Inventor Michael S. Donnenberg

Michael S. Donnenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pathogenic associated protein
    Patent number: 8021861
    Abstract: The present invention provides a polypeptide, called EspA, which is secreted by pathogenic E. coli, such as the enteropathogenic (SPEC) and enterohemorrhagic (EHEC) E. coli. The invention also provides isolated nucleic acid sequences encoding EspA polypeptide, EspA peptides, a recombinant method for producing recombinant EspA, antibodies which bind to EspA, and a kit for the detection of EspA-producing E. coli.
    Type: Grant
    Filed: March 29, 2007
    Date of Patent: September 20, 2011
    Assignee: University of British Columbia
    Inventors: B. Brett Finlay, Brendan Kenny, Markus Stein, Michael S. Donnenberg, Li-Ching Lai
  • Pathogenic Escherichia Coli Associated Protein
    Publication number: 20110003339
    Abstract: The present invention provides a polypeptide, called EspA, which is secreted by pathogenic E. coli, such as the enteropathogenic (SPEC) and enterohemorrhagic (EHEC) E. coli. The invention also provides isolated nucleic acid sequences encoding EspA polypeptide, EspA peptides, a recombinant method for producing recombinant EspA, antibodies which bind to EspA, and a kit for the detection of EspA-producing E. coli.
    Type: Application
    Filed: March 29, 2007
    Publication date: January 6, 2011
    Applicant: The University of British Columbia
    Inventors: B. Brett Finlay, Brendan Kenny, Markus Stein, Michael S. Donnenberg, Li-Ching Lai
  • Pathogenic associated protein
    Patent number: 7214499
    Abstract: The present invention provides a polypeptide, called EspA, which is secreted by pathogenic E. coli, such as the enteropathogenic (SPEC) and enterohemorrhagic (EHEC) E. coli. The invention also provides isolated nucleic acid sequences encoding EspA polypeptide, EspA peptides, a recombinant method for producing recombinant EspA, antibodies which bind to EspA, and a kit for the detection of EspA-producing E. coli.
    Type: Grant
    Filed: April 25, 2006
    Date of Patent: May 8, 2007
    Assignee: University of British Columbia
    Inventors: B. Brett Finlay, Brendan Kenny, Markus Stein, Michael S. Donnenberg, Li-Ching Lai
  • Pathogenic associated protein espA
    Patent number: 7078193
    Abstract: The present invention provides a polypeptide, called EspA, which is secreted by pathogenic E. coli, such as the enteropathogenic (EPEC) and enterohemorrhagic (EHEC) E. coli. The invention also provides isolated nucleic acid sequences encoding EspA polypeptide, EspA peptides, a recombinant method for producing recombinant EspA, antibodies which bind to EspA, and a kit for the detection of EspA-producing E. coli.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: July 18, 2006
    Assignee: University of British Columbia
    Inventors: B. Brett Finlay, Brendan Kenny, Markus Stein, Michael S. Donnenberg, Li-Ching Lai
  • Pathogenic escherichia coli associated protein
    Publication number: 20020115829
    Abstract: The present invention provides a polypeptide, called EspA, which is secreted by pathogenic E. coli, such as the enteropathogenic (EPEC) and enterohemorrhagic (EHEC) E. coli. The invention also provides isolated nucleic acid sequences encoding EspA polypeptide, EspA peptides, a recombinant method for producing recombinant EspA, antibodies which bind to EspA, and a kit for the detection of EspA-producing E. coli.
    Type: Application
    Filed: September 28, 2001
    Publication date: August 22, 2002
    Inventors: B. Brett Finlay, Brendan Kenny, Markus Stein, Michael S. Donnenberg, Li-Ching Lai
  • Pathogenic Escherichia coli associated protein EspA
    Patent number: 6355254
    Abstract: The present invention provides the EspA polypeptide, which is secreted by pathogenic E coli, such as the enteropathogenic (EPEC) and enterohemorrhagic (EHEC) E coli. Diagnosis of disease caused by such pathogenic E coli can be performed by standard techniques, such as those based upon the use of antibodies which bind to EspA to detect the protein, as well as those based on the use of nucleic acid probes for detection of nucleic acids encoding EspA protein. The invention also provides isolated nucleic acid sequences encoding EspA, EspA polypeptide, EspA peptides, a method for producing recombinant EspA, antibodies which bind to EspA, and a kit for the detection of EspA-producing E coli. The invention also provides a method of immunizing a host with EspA to induce a protective immune response to EspA.
    Type: Grant
    Filed: August 10, 1999
    Date of Patent: March 12, 2002
    Assignee: University of British Columbia
    Inventors: B. Brett Finlay, Brendan Kenny, Markus Stein, Michael S. Donnenberg, Li-Ching Lai