Patents by Inventor Michael S. Eison

Michael S. Eison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treatment of ischemia in brain
    Patent number: 5055470
    Abstract: A process for protecting brain cells from ischemia and for treating ischemic and degenerative brain disorders. The process involves systemic administration of BMY 14802 or a pharmaceutically acceptable acid addition salt and/or hydrate.
    Type: Grant
    Filed: June 1, 1989
    Date of Patent: October 8, 1991
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Christopher G. Boissard, Duncan P. Taylor, Michael S. Eison
  • THAZ derivatives for enhancement of cerebral function
    Patent number: 4859666
    Abstract: Tetrahydro-isoxazolo[4,5-d]azepine derivatives possess antiamnesic properties and are cognition enhancers.
    Type: Grant
    Filed: July 6, 1988
    Date of Patent: August 22, 1989
    Assignee: Bristol-Myers Company
    Inventors: Michael S. Eison, Povl Krogsgaard-Larsen
  • Method for alleviation of vascular headache
    Patent number: 4847252
    Abstract: Tiospirone and its pharmaceutically acceptable salts are useful in alleviation of vascular or vascular-related headaches such as migraine, cluster, muscle-contraction, and combined headaches.
    Type: Grant
    Filed: October 25, 1988
    Date of Patent: July 11, 1989
    Assignee: Bristol-Myers Company
    Inventors: Davis L. Temple, Michael F. Rafferty, Michael S. Eison, Stacy N. Suberg
  • Cerebral function enhancing diazinylpiperidine derivatives
    Patent number: 4826843
    Abstract: A series of diazinylpiperidine compounds of Formula I ##STR1## wherein X is an ethylene chain or a 1,2-benzo ring; Y is carbonyl or methylene; R.sup.1 is hydrogen or lower alkyl; and Z is an R.sup.2, R.sup.3 -disubstituted diazinyl ring selected from pyridazine, pyrimidine, and pyrazine ring systems. Pharmacologic and neuroanatomical testing demonstrates that compounds of the series act to enhance cerebral function in mammals, particularly when there is a deficit in normal cerebral functioning. Specific pharmacologic test results indicate that compounds of Formula I possess cognition and memory enhancing activity.
    Type: Grant
    Filed: August 28, 1987
    Date of Patent: May 2, 1989
    Assignee: Bristol-Myers
    Inventors: Ronald J. Mattson, Joseph P. Yevich, Michael S. Eison
  • Anxiolytic method
    Patent number: 4409223
    Abstract: 1-(2-Pyrimidinyl)piperazine and its pharmaceutically acceptable salts are useful in the alleviation of anxiety.
    Type: Grant
    Filed: August 6, 1982
    Date of Patent: October 11, 1983
    Inventors: Leslie A. Riblet, Michael S. Eison