Abstract: Devices, systems, and methods are provided for enhanced geographical caching of estimated arrival times. A method may include receiving respective user inputs indicative of respective users being in transit to a destination location from within a geographic region; determining, for the first user and the second user, a first estimated time of arrival from a first geographical area to the destination location, the first geographical area including the first location and the second location; identifying a third location of the first device at a third time, wherein the third location is within the first geographical area; determining that a time-to-live (TTL) of the first estimated time of arrival has not expired at the third time; and refraining from recalculating the first estimated time of arrival.

Abstract: Methods for sensitive and reliable qualitative detection and identification of the common pathogens associated with ocular infections, including uveitis, endophthalmitis and keratitis.

Abstract: Compositions comprising antigenic peptides, and their use in inducing an immunoprotective response in a subject against an infection with Streptococcus pneumonia, or for treating or preventing, i.e., reducing risk of, an infection of Streptococcus pneumonia.

Abstract: Compositions comprising antigenic peptides, and their use in inducing an immunoprotective response in a subject against an infection with Streptococcus pneumonia, or for treating or preventing, i.e., reducing risk of, an infection of Streptococcus pneumonia.

Abstract: Provided herein are methods for inducing cell death in a gram positive bacterium and methods for reducing the proliferation of a gram positive bacterium that include contacting a gram positive bacterium with a dye (e.g., an azo dye) and a TarO inhibitor. Also provided are methods of treating a subject having a gram positive bacterial infection that include administering to a subject having a gram positive bacterial infection a dye (e.g., an azo dye) and a TarO inhibitor. Also provided are compositions containing a dye (e.g., an azo dye) and a TarO inhibitor, and kits containing at least one of these compositions.

Abstract: Provided herein are methods for inducing cell death in a gram positive bacterium and methods for reducing the proliferation of a gram positive bacterium that include contacting a gram positive bacterium with a dye (e.g., an azo dye) and a TarO inhibitor. Also provided are methods of treating a subject having a gram positive bacterial infection that include administering to a subject having a gram positive bacterial infection a dye (e.g., an azo dye) and a TarO inhibitor. Also provided are compositions containing a dye (e.g., an azo dye) and a TarO inhibitor, and kits containing at least one of these compositions.