Abstract: The present invention is based on the finding that enrichment of D3-creatinine in a urine sample following oral administration of a single defined dose of D3-creatine can be used to calculate total-body creatine pool size and total body skeletal muscle mass in a subject. The invention further encompasses methods for detecting creatinine and D3-creatinine in a single sample. The methods of the invention find use, inter alia, in diagnosing disorders related to skeletal muscle mass, and in screening potential therapeutic agents to determine their effects on muscle mass.

Abstract: A suction drum dryer, for knitted fabrics and the like, is provided with an adjustable width bellows mechanism for masking side margins of the drums not occupied by the fabric web. Ambient air draw into the suction drums is thus caused to flow substantially exclusively through the material to be processed. Significantly improved operating efficiencies are realized, as well as significantly higher production output from a given piece of equipment.