Abstract: The disclosure relates to barcoded polymer nanoparticles for in vivo screening and for in vivo therapeutic delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticles, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, associated with polynucleotide barcodes, for therapeutic delivery, and for high throughput in vivo screening of drug delivery nanoparticles.

Abstract: The invention relates to barcoded nucleic acid nanostructure delivery compositions for in vivo screening for subsequent use in vivo therapeutic delivery, and methods therefor. More particularly, the invention relates to nucleic acid nanostructure delivery compositions, such as DNA origami structures, associated with barcodes for high throughput in vivo screening of the nucleic acid nanostructure delivery compositions for subsequent use in drug delivery, and methods therefor.

Abstract: A digital magazine server generates a digital magazine for user based on a received request for the digital magazine identifying one or more topics. The digital magazine server applies one or more machined trained models to obtained content items to select content items for the topic. A hierarchy of the topics included in the received request may be determined by the digital magazine server and used by the trained models to select content items. When generating the digital magazine, the digital magazine server also includes one or more editorial content items that are manually selected. The digital magazine serer may reposition one or more content items selected by the trained models to include an editorial content items.

Abstract: A digital magazine server generates a digital magazine for user based on a received request for the digital magazine identifying one or more topics. The digital magazine server applies one or more machined trained models to obtained content items to select content items for the topic. A hierarchy of the topics included in the received request may be determined by the digital magazine server and used by the trained models to select content items. When generating the digital magazine, the digital magazine server also includes one or more editorial content items that are manually selected. The digital magazine serer may reposition one or more content items selected by the trained models to include an editorial content items.

Abstract: A digital magazine server generates a digital magazine for user based on a received request for the digital magazine identifying one or more topics. The digital magazine server applies one or more machined trained models to obtained content items to select content items for the topic. A hierarchy of the topics included in the received request may be determined by the digital magazine server and used by the trained models to select content items. When generating the digital magazine, the digital magazine server also includes one or more editorial content items that are manually selected. The digital magazine server may reposition one or more content items selected by the trained models to include an editorial content items.

Abstract: A digital magazine server generates a digital magazine for user based on a received request for the digital magazine identifying one or more topics. The digital magazine server applies one or more machined trained models to obtained content items to select content items for the topic. A hierarchy of the topics included in the received request may be determined by the digital magazine server and used by the trained models to select content items. When generating the digital magazine, the digital magazine server also includes one or more editorial content items that are manually selected. The digital magazine server may reposition one or more content items selected by the trained models to include an editorial content items.

Abstract: A digital magazine server generates a digital magazine for user based on a received request for the digital magazine identifying one or more topics. The digital magazine server applies one or more machined trained models to obtained content items to select content items for the topic. A hierarchy of the topics included in the received request may be determined by the digital magazine server and used by the trained models to select content items. When generating the digital magazine, the digital magazine server also includes one or more editorial content items that are manually selected. The digital magazine serer may reposition one or more content items selected by the trained models to include an editorial content items.

Abstract: Systems and methods for enabling users to rapidly flip through displayed pages of content in an intuitive manner are provided. Graphical animations for transitioning from one page to another can be executed so that portions of three or more pages can be simultaneously viewed. This enables a user to make snap judgments as to whether she wishes to explore anyone of those pages in more detail as she rapidly flips through the pages.

Abstract: Systems and methods for enabling users to rapidly flip through displayed pages of content in an intuitive manner are provided. Graphical animations for transitioning from one page to another can be executed so that portions of three or more pages can be simultaneously viewed. This enables a user to make snap judgments as to whether she wishes to explore anyone of those pages in more detail as she rapidly flips through the pages.

Abstract: Systems and methods for enabling users to rapidly flip through displayed pages of content in an intuitive manner are provided. Graphical animations for transitioning from one page to another can be executed so that portions of three or more pages can be simultaneously viewed. This enables a user to make snap judgments as to whether she wishes to explore any one of those pages in more detail as she rapidly flips through the pages.

Abstract: A digital magazine server creates cover pages identifying relevant content items relevant to a user. Candidate feeds of content items are identified from various sources, such as user-defined sections of content items, social networking systems, external content providers, and recommended content. The digital magazine server retrieves content items from the candidate feeds and generates clusters including retrieved content items based at least in part on the content elements contained in the content items. The content items in various clusters are scored, and one or more content items are selected from each cluster. The selected content items are placed in a consolidated feed, which is used to create a cover page describing a digital magazine for presentation to a digital magazine server user.

Abstract: Systems and methods for enabling users to rapidly flip through displayed pages of content in an intuitive manner are provided. Graphical animations for transitioning from one page to another can be executed so that portions of three or more pages can be simultaneously viewed. This enables a user to make snap judgments as to whether she wishes to explore any one of those pages in more detail as she rapidly flips through the pages.

Abstract: A method of accessing and updating an electronic phonebook over electronic communications networks such as a telephone and computer networks is described. The creation of a voice portal is supported by the invention. Embodiments of the invention use telephone identifying information such as the calling party's number to identify, or create, user profiles for customization. The user profile can include personalized phonebook entries that include names and telephone numbers of relevance to the user. Additionally, the voice portal can connect the user to numbers contained in the personalized phonebook in response to spoken commands. The profile can also be updated with additional phonebook entries over the interne using a web browser.

Abstract: A method and apparatus for providing personalized information content over telephones is described. The creation of a voice portal is supported by the invention. Embodiments of the invention use telephone identifying information such as the calling party's number to identify, or create, user profiles for customization. The personalized content is specific to that user based on her/his telephone identifying information and may be further customized based on the current time, current date, the calling party's locales, and/or the calling party's dialect and speech patterns. In some embodiments, the dialect is selected from a range of common American English dialects according to the locale of the calling party. For example, callers from the Northern Midland will automatically hear a Northern Midland dialect, while callers from the Coastal Southeast will hear that dialect, etc. Individuals can change the dialect to better suit their personal tastes.

Abstract: A voice portal supporting telephone to web server commerce is described. The voice portal allows users to access web servers using a hypertext transfer protocol (HTTP), optionally including the use of a secure sockets layer (SSL) protocol, to complete commercial transactions. Additionally, embodiments of the invention can employ a one word commerce model that abstracts the particular model used by various electronic commerce vendors' web sites. The one word commerce model permits a user to identify a product and signal her/his purchase intentions with a single word, phrase, or touch-tone command. The voice portal can then complete the transaction supplying the electronic commerce vendor necessary information about the purchaser, e.g., her/his address, telephone number, electronic mail address, credit card information, etc. As needed, the voice portal can prompt the purchaser for information.

Abstract: A method and apparatus for providing personalized information content over telephones is described. The creation of a voice portal is supported by the invention. Embodiments of the invention use telephone identifying information such as the calling party's number to identify, or create, user profiles for customization. The personalized content is specific to that user based on her/his telephone identifying information and may be further customized based on the current time, current date, the calling party's locales, and/or the calling party's dialect and speech patterns. Also, the telephone identifying information may support targeted advertising, content, and purchasing recommendations specific to that user. The system may use a voice password and/or touch-tone login system when appropriate to distinguish the caller or verify the caller's identity for specific activities.

Abstract: A method and apparatus for providing streaming content over telephones is described. The creation of a voice portal is supported by the invention. Embodiments of the invention use allows users to place a telephone call to access the voice portal. The user can access many different types of content. This content can include text based content which is read to the user by a text to speech system (e.g., news reports, stock prices, text content of Internet sites), audio content which can be played to the user (e.g., voicemail messages, music), and streaming audio content (e.g., Internet broadcast radio shows, streaming news reports, and streaming live broadcasts). This content can be accessed from many different places. For example, the content can be retrieved from a news feed, a local streaming content server, an audio repository, and/or an Internet based streaming content server. The streaming content allows the user to access live web broadcasts even though the user may not have access to a computer.

Abstract: A method and apparatus for providing personalized information content over telephones is described. The creation of a voice portal is supported by the invention. Embodiments of the invention use telephone identifying information such as the calling party's number to identify, or create, user profiles for customization. The personalized content is specific to that user based on her/his telephone identifying information and may be further customized based on the current time, current date, the calling party's locales, and/or the calling party's dialect and speech patterns. Also, the telephone identifying information may support targeted advertising, content, and purchasing recommendations specific to that user. The system may use a voice password and/or touch-tone login system when appropriate to distinguish the caller or verify the caller's identity for specific activities.

Abstract: A method and apparatus for providing personalized information content over telephones is described. The creation of a voice portal is supported by the invention. Embodiments of the invention use telephone identifying information such as the calling party's number to identify, or create, user profiles for customization. The personalized content is specific to that user based on her/his telephone identifying information and may be further customized based on the current time, current date, the calling party's locales, and/or the calling party's dialect and speech patterns. Also, the telephone identifying information may support targeted advertising, content, and purchasing recommendations specific to that user. The system may use a voice password and/or touch-tone login system when appropriate to distinguish the caller or verify the caller's identity for specific activities.

Abstract: A phone based loyalty rewards approach is described. The approach focuses on rewarding certain behaviors by maintaining a rewards balance usable for services such as free telephone calls. Users can be awarded some initial value of rewards balance at registration and then can earn additional rewards through their activities. Calls can be placed using voice dialing against a user supplied address book in one embodiment. Additionally, the rewards can be directly integrated with an advanced dial tone service offering and minutes spent on phone calls beyond the then available rewards balance charged to the user. The rewards are designed to encourage behaviors such as full and accurate registrations, regular usage, trying new features, etc.