Abstract: A treatment system delivers a breathing gas and frozen ice or other particles (FSP) to a bronchus of a lung of a patient in order to induce hypothermia. The breathing gas and the FSP are usually delivered through separate lumens. Clogging of an FSP lumen can be inhibited by heating and/or cooling of the lumen. The temperature of exhaled gases or a body temperature may be measured, and a controller can adjust the duration or rate at which the ice particles are delivered in order to control the patient's core temperature based on the measured temperature.

Abstract: A device having multiple chambers may be configured to expand to contact a substantial section of an interior wall of a body structure or lumen in order to simultaneously exclude blood or other liquid from a target structure while providing for delivery of a therapeutic agent directly to the interior wall. The expandable device may be manufactured from a plurality of flat sheets of material heat sealed to one another to form an inflation chamber and one, two or more delivery chambers. The sheets may also be bonded to an elongate catheter body having inflation and delivery lumens. The excluding of blood flow and delivery of therapeutic agents are completed by the same device.

Abstract: Apparatus and methods for generating foam are disclosed. The inventions can be used for generating foam for sclerotherapy. A foaming element can be agitated within a foaming chamber by a drive unit that does not touch the foaming element, but actuates it from outside the foaming chamber. The foaming element and drive unit can be magnetically coupled. A syringe can be used to form a foaming chamber.

Abstract: An apparatus for introducing an implant into a hollow anatomical structure. The apparatus comprises a storage unit; an elongate vascular implant stored inside the storage unit and having a distal end; and a pushrod at least partially stored inside the storage unit and having a distal end coupled to the distal end of the implant. The implant diverges from adjacency with the pushrod as the implant extends away from the distal end of the pushrod, such that the pushrod forms a force application region near the distal end of the pushrod. The force application region is accessible for force application but separated from the implant.

Abstract: An apparatus for treating a hollow anatomical structure can include a light delivery device. The light delivery device comprises an optical fiber that is located in a lumen of a shaft suitable for insertion into the hollow anatomical structure and has a fiber tip located proximal of a distal end of the shaft during treatment of the hollow anatomical structure. The apparatus can further include a liquid source for providing a liquid flow over the optical fiber at a predetermined liquid flow rate.

Abstract: Apparatus for advancing a vascular implant into a blood vessel. The apparatus comprises a first elongate member, the first elongate member having sufficient column strength to function as a pusher member; and a second elongate member, the second elongate member being thinner than the first elongate member and extending to a distal end located at a first point which is at or near a distal end of the first elongate member. The elongate members form an implant retaining portion while the distal end of the second elongate member is located at the first point. The implant retaining portion is located proximal of the first point. The implant retaining portion comprises a space located between the elongate members and configured for receiving an implant portion, with the first elongate member on one side of the space and the second elongate member on another side. The implant retaining portion further comprises a proximal side and a distal side which further circumscribe the space.

Abstract: In certain embodiments, the system is configured to remove from or fragment materials in a vessel by inserting a catheter into a vessel, wherein the distal tip of the catheter is placed at the surgical site and a liquid spray is applied to materials to remove or fragment (as defined herein) the materials. In certain embodiments, the system comprises a liquid spray emanating from a fragmentation lumen and across a fragmentation opening.

Abstract: The various embodiments simplify the delivery of an occlusive implant to a hollow anatomical structure, such as a fallopian tube. For example, the delivery devices don't need to be retracted manually to deploy the implant. When the devices are activated, stored energy or a powered drive member induces movement of the various components. The operator need only position the distal ends of the devices at the treatment site and then commence deployment by, for example, flipping a switch or changing the position of an activation button. The present embodiments thus increase the efficacy of occlusion procedures by reducing the likelihood of operator error.

Abstract: A device having multiple chambers may be configured to expand to contact a substantial section of an interior wall of a body structure or lumen in order to simultaneously exclude blood or other liquid from a target structure while providing for delivery of a therapeutic agent directly to the interior wall. The expandable device may be manufactured from a plurality of flat sheets of material heat sealed to one another to form an inflation chamber and one, two or more delivery chambers. The sheets may also be bonded to an elongate catheter body having inflation and delivery lumens. The excluding of blood flow and delivery of therapeutic agents are completed by the same device.

Abstract: A catheter is usable to treat a hollow anatomical structure (HAS). The catheter comprises one or more shafts which extend away from a proximal end of the catheter toward a distal end thereof. The catheter further comprises an HAS constriction energy source located at or near the distal end of the catheter. The catheter further comprises at least one radially expandable transmural fluid delivery channel located in the catheter near the HAS constriction energy source.

Abstract: An apparatus for treating a hollow anatomical structure comprises an implant comprising a plurality of bioabsorbable fibers. The implant has a compressed state in which the implant can fit within a cylindrical tube having an inside diameter of 8 French or less. The implant is expandable from the compressed state to an expanded state in which the implant has sufficient size to span the inside diameter of a cylindrical tube having an inside diameter of 12 French or greater.

Abstract: Apparatus and methods for treating a hollow anatomical structure comprises an implant sized for insertion into a hollow anatomical structure. The implant comprises a plurality of loose, bulked fibers. The fibers are formed from one or more bioabsorbable materials. Upon implantation, the apparatus causes a partial occlusion of the hollow anatomical structure, followed by a complete or substantially complete occlusion.

Abstract: An electrosurgical ablation device provides pulse width modulated DC power to a heating segment in a catheter for use in providing treatment. In some embodiments the DC power to be modulated is sourced from an AC/DC power converter coupled to a source of AC power. In some embodiments the DC power to be modulated is sourced from a battery. In some embodiments the device switchably selects for modulation DC power sourced from either the AC/DC power converter or the battery, for example based on availability of power from the AC/DC power converter.

Abstract: A method of treating a hollow anatomical structure of a patient comprises implanting a bioabsorbable fibrous body in a hollow anatomical structure. The body is secured in the hollow anatomical structure to limit migration of the body within the hollow anatomical structure.

Abstract: An energy delivering probe is used for thermally coagulating and/or constricting hollow anatomical structures (HAS) including, but not limited to, blood vessels such as perforator veins. The probe includes a shaft and an energy source.

Abstract: A catheter is usable to treat a hollow anatomical structure (HAS). The catheter comprises one or more shafts which extend away from a proximal end of the catheter toward a distal end thereof. The catheter further comprises an HAS constriction energy source located at or near the distal end of the catheter. The catheter further comprises at least one radially expandable transmural fluid delivery channel located in the catheter near the HAS constriction energy source.

Abstract: An apparatus for treating a hollow anatomical structure can include a light delivery device. The light delivery device comprises an optical fiber that is located in a lumen of a shaft suitable for insertion into the hollow anatomical structure and has a fiber tip located proximal of a distal end of the shaft during treatment of the hollow anatomical structure. The apparatus can further include a liquid source for providing a liquid flow over the optical fiber at a predetermined liquid flow rate.

Abstract: An energy delivering probe is used for thermally coagulating and/or constricting hollow anatomical structures (HAS) including, but not limited to, blood vessels such as perforator veins. The probe includes a shaft and at least two electrodes where at least one of the electrodes has a generally spherical or toroidal geometry.

Abstract: Apparatus and methods for generating foam are disclosed. The inventions can be used for generating foam for sclerotherapy. A foaming element can be agitated within a foaming chamber by a drive unit that does not touch the foaming element, but actuates it from outside the foaming chamber. The foaming element and drive unit can be magnetically coupled. A syringe can be used to form a foaming chamber.

Abstract: Apparatus and methods for generating foam are disclosed. The inventions can be used for generating foam for sclerotherapy. A foaming element can be agitated within a foaming chamber by a drive unit that does not touch the foaming element, but actuates it from outside the foaming chamber. The foaming element and drive unit can be magnetically coupled. A syringe can be used to form a foaming chamber.