Abstract: Methods of forming supple tissue dressing assemblies from hydrophilic polymer sponge structures, such as chitosan, by uniformly cooling the sponge structure and freezer from above freezing to below freezing. The supple tissue dressing assemblies are characterized by suppleness or multi-dimensional flexibility. The assemblies can be flexed, bent, folded, twisted, and even rolled upon itself before and during use, without creasing, cracking, fracturing, otherwise compromising the integrity and mechanical and/or therapeutic characteristics of the assemblies.