Abstract: A protective safety container for encasing toxic drug filled glass vials is disclosed. The container includes a molded plastic body that is shaped to conform to the shape of a vial to be protected. A plurality of spaced longitudinal ribs are formed on the inner surface of the container body that act to engage the vial and hold it firmly in position, and also form a cushioning air space between the vial and the container. A molded plastic annular base is adapted to be snap fitted into the body such that the vial cannot be easily removed once it is secured within the container. Disposed in the top of the container is a small aperture having a frangible disk disposed therein. The disk may be removed so that a hypodermic needle may be inserted into a stopper in the vial to withdraw the vial's contents. The aperture is too small, however, to permit removal of the stopper itself.