Patents by Inventor Michael S. Sacks

Michael S. Sacks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9744267
    Abstract: A rapid method for preparing stem cell and physiologically acceptable matrix compositions for use in tissue and organ repair is described. Compared with previous tissue engineering materials, the stem cell-matrix compositions of the present invention do not require long-term incubation or cultivation in vitro prior to use in in vivo applications. The stem cells can be from numerous sources and may be homogeneous, heterogeneous, autologous, and/or allogeneic in the matrix material. The stem cell-matrix compositions provide point of service utility for the practitioner, wherein the stem cells and matrix can be combined not long before use, thereby alleviating costly and lengthy manufacturing procedures. In addition, the stem cells offer unique structural properties to the matrix composition which improves outcome and healing after use. Use of stem cells obtained from muscle affords contractility to the matrix composition.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: August 29, 2017
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Michael B. Chancellor, Johnny Huard, Christopher C. Capelli, Steve Chung, Michael S. Sacks
  • Publication number: 20160101217
    Abstract: A rapid method for preparing stem cell and physiologically acceptable matrix compositions for use in tissue and organ repair is described. Compared with previous tissue engineering materials, the stem cell-matrix compositions of the present invention do not require long-term incubation or cultivation in vitro prior to use in in vivo applications. The stem cells can be from numerous sources and may be homogeneous, heterogeneous, autologous, and/or allogeneic in the matrix material. The stem cell-matrix compositions provide point of service utility for the practitioner, wherein the stem cells and matrix can be combined not long before use, thereby alleviating costly and lengthy manufacturing procedures. In addition, the stem cells offer unique structural properties to the matrix composition which improves outcome and healing after use. Use of stem cells obtained from muscle affords contractility to the matrix composition.
    Type: Application
    Filed: December 17, 2015
    Publication date: April 14, 2016
    Inventors: Michael B. Chancellor, Johnny Huard, Christopher C. Capelli, Steve Chung, Michael S. Sacks
  • Publication number: 20150017220
    Abstract: A rapid method for preparing stem cell and physiologically acceptable matrix compositions for use in tissue and organ repair is described. Compared with previous tissue engineering materials, the stem cell-matrix compositions of the present invention do not require long-term incubation or cultivation in vitro prior to use in in vivo applications. The stem cells can be from numerous sources and may be homogeneous, heterogeneous, autologous, and/or allogeneic in the matrix material. The stem cell-matrix compositions provide point of service utility for the practitioner, wherein the stem cells and matrix can be combined not long before use, thereby alleviating costly and lengthy manufacturing procedures. In addition, the stem cells offer unique structural properties to the matrix composition which improves outcome and healing after use. Use of stem cells obtained from muscle affords contractility to the matrix composition.
    Type: Application
    Filed: July 2, 2014
    Publication date: January 15, 2015
    Inventors: Michael B. Chancellor, Johnny Huard, Christopher C. Capelli, Steve Chung, Michael S. Sacks
  • Patent number: 8852923
    Abstract: Described herein is a bioreactor system and modules capable of developing physiologically relevant fluid-induced shear stresses and regionally specific flow patterns to scaffold specimens and which can couple these stresses to cyclic flexure and/or stretch states. Methods of use of the bioreactor system and module also are provided.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: October 7, 2014
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Steven M. Boronyak, George C. Engelmayr, Jr., Sharan Ramaswamy, Michael S. Sacks, David E. Schmidt, Mohammed S. El-Kurdi
  • Patent number: 8790680
    Abstract: A rapid method for preparing stem cell and physiologically acceptable matrix compositions for use in tissue and organ repair is described. Compared with previous tissue engineering materials, the stem cell-matrix compositions of the present invention do not require long-term incubation or cultivation in vitro prior to use in in vivo applications. The stem cells can be from numerous sources and may be homogeneous, heterogeneous, autologous, and/or allogeneic in the matrix material. The stem cell-matrix compositions provide point of service utility for the practitioner, wherein the stem cells and matrix can be combined not long before use, thereby alleviating costly and lengthy manufacturing procedures. In addition, the stem cells offer unique structural properties to the matrix composition which improves outcome and healing after use. Use of stem cells obtained from muscle affords contractility to the matrix composition.
    Type: Grant
    Filed: March 11, 2011
    Date of Patent: July 29, 2014
    Assignee: University of Pittsburg—Of the Commonwealth System of Higher Education
    Inventors: Michael B. Chancellor, Johnny Huard, Christopher Capelli, Steve Chung, Michael S. Sacks
  • Publication number: 20110223139
    Abstract: A rapid method for preparing stem cell and physiologically acceptable matrix compositions for use in tissue and organ repair is described. Compared with previous tissue engineering materials, the stem cell-matrix compositions of the present invention do not require long-term incubation or cultivation in vitro prior to use in in vivo applications. The stem cells can be from numerous sources and may be homogeneous, heterogeneous, autologous, and/or allogeneic in the matrix material. The stem cell-matrix compositions provide point of service utility for the practitioner, wherein the stem cells and matrix can be combined not long before use, thereby alleviating costly and lengthy manufacturing procedures. In addition, the stem cells offer unique structural properties to the matrix composition which improves outcome and healing after use. Use of stem cells obtained from muscle affords contractility to the matrix composition.
    Type: Application
    Filed: March 11, 2011
    Publication date: September 15, 2011
    Inventors: Michael B. Chancellor, Johnny Huard, Christopher Capelli, Steve Chung, Michael S. Sacks
  • Publication number: 20110212500
    Abstract: Described herein is a bioreactor system and modules capable of developing physiologically relevant fluid-induced shear stresses and regionally specific flow patterns to scaffold specimens and which can couple these stresses to cyclic flexure and/or stretch states. Methods of use of the bioreactor system and module also are provided.
    Type: Application
    Filed: December 3, 2010
    Publication date: September 1, 2011
    Inventors: Steven M. Boronyak, George C. Engelmayr, JR., Sharan Ramaswamy, Michael S. Sacks, David E. Schmidt, Mohammed S. El-Kurdi
  • Patent number: 7906110
    Abstract: The invention is directed to preparation of stem cell and physiologically acceptable matrix compositions. Compared with previous tissue engineering materials, the stem cell-matrix compositions of the present invention do not require long-term incubation or cultivation in vitro prior to use in vivo applications. The stem cells can be from numerous sources and may be homogeneous, heterogeneous, autologous, and/or allogeneic in the matrix material. The stem cell-matrix compositions provide point of service utility for the practitioner, wherein the stem cells and matrix can be combined not long before use, thereby alleviating costly and lengthy manufacturing procedures. In addition, the stem cells offer unique structural properties to the matrix composition which improves outcome and healing after use. Use of stem cells obtained from muscle affords contractility to the matrix composition.
    Type: Grant
    Filed: May 25, 2005
    Date of Patent: March 15, 2011
    Assignee: University of Pittsburgh—of the Commonwealth System of Higher Education
    Inventors: Michael B. Chancellor, Johnny Huard, Christopher Capelli, Steve Chung, Michael S. Sacks
  • Publication number: 20020155096
    Abstract: The present invention describes a rapid method for preparing stem cell and physiologically acceptable matrix compositions for use in tissue and organ repair. Compared with previous tissue engineering materials, the stem cell-matrix compositions of the present invention do not require long-term incubation or cultivation in vitro prior to use in in vivo applications. The stem cells can be from numerous sources and may be homogeneous, heterogeneous, autologous, and/or allogeneic in the matrix material. The stem cell-matrix compositions as described provide point of service utility for the practitioner, wherein the stem cells and matrix can be combined not long before use, thereby alleviating costly and lengthy manufacturing procedures. In addition, the stem cells offer unique structural properties to the matrix composition which improves outcome and healing after use. Use of stem cells obtained from muscle affords contractility to the matrix composition.
    Type: Application
    Filed: February 22, 2002
    Publication date: October 24, 2002
    Inventors: Michael B. Chancellor, Johnny Huard, Christopher Capelli, Steve Chung, Michael S. Sacks