Abstract: Disclosed are compounds of Formula (I): or stereoisomers, tautomers, or salts thereof, wherein: R is and Ring A, L, R1, R2, R3, m, and n are defined herein. Also disclosed are methods of using such compounds to decrease the level Cyclin E1; and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of proliferative disorders, such as cancer.

Abstract: In one embodiment, a processor includes a frontend unit having an instruction decoder to receive and to decode instructions of a plurality of threads, an execution unit coupled to the instruction decoder to receive and execute the decoded instructions, and an instruction retirement unit having a retirement logic to receive the instructions from the execution unit and to retire the instructions associated with one or more of the threads that have an instruction or an event pending to be retired. The instruction retirement unit includes a thread arbitration logic to select one of the threads at a time and to dispatch the selected thread to the retirement logic for retirement processing.

Abstract: In one embodiment, a processor includes a frontend unit having an instruction decoder to receive and to decode instructions of a plurality of threads, an execution unit coupled to the instruction decoder to receive and execute the decoded instructions, and an instruction retirement unit having a retirement logic to receive the instructions from the execution unit and to retire the instructions associated with one or more of the threads that have an instruction or an event pending to be retired. The instruction retirement unit includes a thread arbitration logic to select one of the threads at a time and to dispatch the selected thread to the retirement logic for retirement processing.

Abstract: A cooling system for an electrical motor or generator includes a first cooling loop, a second cooling loop, and a heat exchange system. The first cooling loop may extract heat from an iron stack and winding of the electrical motor or generator. The second cooling loop may extract heat from end turns of the stator winding, the rotor, and the bearings independently from and simultaneously to the first cooling loop. At least the first cooling loop may pass through the heat exchange system. A liquid coolant may circulate in the first cooling loop and a compressed gas, such as compressed air or compressed refrigerant in vapor form, may circulate in the second cooling loop. The cooling system and method for an electrical motor or generator may be suitable for, but not limited to, applications in the aircraft and aerospace industries, such as driving a cabin air compressor of an aircraft.

Abstract: A cooling system for an electrical motor or generator includes a first cooling loop, a second cooling loop, and a heat exchange system. The first cooling loop may extract heat from an iron stack and winding of the electrical motor or generator. The second cooling loop may extract heat from end turns of the stator winding, the rotor, and the bearings independently from and simultaneously to the first cooling loop. At least the first cooling loop may pass through the heat exchange system. A liquid coolant may circulate in the first cooling loop and a compressed gas, such as compressed air or compressed refrigerant in vapor form, may circulate in the second cooling loop. The cooling system and method for an electrical motor or generator may be suitable for, but not limited to, applications in the aircraft and aerospace industries, such as driving a cabin air compressor of an aircraft.

Abstract: A parallel, scalable internetworking unit (IU) architecture employing at least two network controllers (NCs), a foreground buffer controller with local memory, a background buffer controller with local memory, a node processor (NP) and a buffer memory. Each network attached to the IU has an individual network controller which communicates with the foreground buffer controller. The foreground buffer controller interfaces with NCs and maintains queueing information. The background buffer controller communicates with the foreground buffer controller for maintaining packets of data as linked lists of buffers in the buffer memory. The NP communicates with both the foreground and background buffer controllers to process stored header information. And, a connection matrix is provided to dynamically interconnect multiple IUs for increased parallel processing of packet traffic and processing.