Abstract: A utility consumption information system may generate a variety of data that is based on and/or derived from utility consumption or usage associated with a site. In some examples, the utility consumption information system may generate data to be provided or displayed by applying a load profile to utility consumption or usage data obtained at the site over a period of time. The utility consumption information system may generate the load profile based on sample interval data obtained from one or more devices (e.g., utility metering devices) sharing characteristics with the site at which the utility consumption or usage data was obtained.

Abstract: Certain embodiments are directed to a formulation of a therapeutic agent, as well as a method of making such a formulation, comprising at least one therapeutic agent dissolved in an aprotic polar solvent system comprising at least one ionization stabilizing excipient in a concentration sufficient to impart physical and chemical stability to the therapeutic agent.

Abstract: Certain embodiments are directed to a formulation of a therapeutic agent, as well as a method of making such a formulation, comprising at least one therapeutic agent dissolved in an aprotic polar solvent system comprising at least one ionization stabilizing excipient in a concentration sufficient to impart physical and chemical stability to the therapeutic agent.

Abstract: Certain embodiments are directed to a formulation of a therapeutic agent, as well as a method of making such a formulation, comprising at least one therapeutic agent dissolved in an aprotic polar solvent system comprising at least one ionization stabilizing excipient in a concentration sufficient to impart physical and chemical stability to the therapeutic agent.

Abstract: Certain embodiments are directed to a formulation of a therapeutic agent, as well as a method of making such a formulation, comprising at least one therapeutic agent dissolved in an aprotic polar solvent system comprising at least one ionization stabilizing excipient in a concentration sufficient to impart physical and chemical stability to the therapeutic agent.

Abstract: Certain embodiments are directed to a formulation of a therapeutic agent, as well as a method of making such a formulation, comprising at least one therapeutic agent dissolved in an aprotic polar solvent system comprising at least one ionization stabilizing excipient in a concentration sufficient to impart physical and chemical stability to the therapeutic agent.

Abstract: Certain embodiments are directed to a formulation of a therapeutic agent, as well as a method of making such a formulation, comprising at least one therapeutic agent dissolved in an aprotic polar solvent system comprising at least one ionization stabilizing excipient in a concentration sufficient to impart physical and chemical stability to the therapeutic agent.

Abstract: The present invention provides methods for controlling or reducing caloric intake in a subject by administering a low dose of a stable glucagon formulation. The present invention further provides methods for treating mild or moderate hypoglycemia in a subject in need thereof subject by administering a low dose of a stable glucagon formulation. Kits for practicing the methods of the invention are also provided.

Abstract: Certain embodiments are directed to a formulation of a therapeutic agent, as well as a method of making such a formulation, comprising at least one therapeutic agent dissolved in an aprotic polar solvent system comprising at least one ionization stabilizing excipient in a concentration sufficient to impart physical and chemical stability to the therapeutic agent.

Abstract: Certain embodiments are directed to a formulation of a therapeutic agent, as well as a method of making such a formulation, comprising at least one therapeutic agent dissolved in an aprotic polar solvent system comprising at least one ionization stabilizing excipient in a concentration sufficient to impart physical and chemical stability to the therapeutic agent.

Abstract: Certain embodiments are directed to a formulation of a therapeutic agent, as well as a method of making such a formulation, comprising at least one therapeutic agent dissolved in an aprotic polar solvent system comprising at least one ionization stabilizing excipient in a concentration sufficient to impart physical and chemical stability to the therapeutic agent.

Abstract: Certain embodiments are directed to a formulation of a therapeutic agent, as well as a method of making such a formulation, comprising at least one therapeutic agent dissolved in an aprotic polar solvent system comprising at least one ionization stabilizing excipient in a concentration sufficient to impart physical and chemical stability to the therapeutic agent.

Abstract: Techniques are described for determining and using information related to domains of interest, such as by automatically analyzing documents and other information related to a domain in order to automatically determine relationships between particular terms within the domain. Such automatically determined information may then be used to assist users in obtaining information from the domain that is of interest (e.g., documents with contents that are relevant to user-specified terms and/or to other terms that are determined to be sufficiently related to the user-specified terms). For example, recommendations may be automatically generated for a user by using information about specified preferences or other interests of the user with respect to one or more terms and identifying other particular terms that are sufficiently probable to be of interest to that user, such as based on a generated probabilistic representation of relationships between particular terms for the domain.

Abstract: The current document is directed to methods and automated systems for handling files and other data during a data ingestion process that may contain PHI within the file content, filenames, file-associated metadata, and other such data-associated information. The methods and automated systems protect sensitive health information using encryption methods to prevent the protected health information from being exposed. In certain implementations, the currently disclosed automated system includes a client-network system, one or more client servers, an encrypted data-storage device including a source folder for temporarily storing original files downloaded from the client network system and a second folder for storing PHI-free files created from the original files, and processes that create the PHI-free files from the original files, remove the original files from the source folder, and securely copy the PHI-free files to a secure file-transfer protocol server to be processed for later use.

Abstract: The current document is directed to methods and systems for estimating values that could be derived from a large data set, were it available, from values computed from an available smaller data set. A specific example of the currently described methods and systems are methods and systems that estimate various medical-record-related statistics and values computed from hypothetical datasets. In order to extrapolate the desired statistics and computed values from the observed smaller data set, multiple models are employed by the currently disclosed methods and systems. These models can be employed sequentially to generate relatively fine-grained estimates over various multi-dimensional data-set volumes.

Abstract: The present document is directed to an automated experimentation platform that provides a visual integrated development environment (“IDE”) that allows a user to construct and execute various types of data-driven workflows. The automated experimentation platform includes back-end components that include API servers, a catalog, a cluster-management component, and execution-cluster nodes. Workflows are visually represents as directed acyclic graphs and texturally encoded. The workflows are transformed into jobs that are distributed for execution to the execution-cluster nodes.

Abstract: Security and distributed storage is described for systems using electronic profile information. Embodiments may be utilized for ID, data, and access analysis. Dynamic distributed redundant encryption may be used that may be based on user, device, location, context information, physical, or environmental characteristics. In one implementation, encrypted electronic profiles are stored on behalf of users by a profiling system, allowing user information within the electronic profiles to be accessed only by decryption of a portion of the electronic profile by the profiling system using distributed decryption codes.

Abstract: The current document is directed to methods and automated systems that assign individual medical codes selected from one or more medical codebooks to electronic medical records. In certain implementations, the currently disclosed automated systems generate multiple streams of medical terms or medical terms and phrases from an electronic medical record as well as multiple streams of medical terms or medical terms and phrases from individual medical codes contained within a medical codebook and then use stream-comparison functionality to select those individual medical codes of the medical codebook most likely to be relevant and related to the information encoded within the electronic medical record.

Abstract: The current document is directed to methods and systems for automated generation of evaluation and management medical codes (“E/M codes”). In one implementation, a series of processes are applied to a medical document in order to generate annotations and concepts, extract metadata, and, using the annotations and concepts, and, in certain cases, the extracted metadata, to generate a set of feature/feature-value pairs that parametrically represent the contents of the medical document. Models for E/M codes and E/M-code components are generated to contain sets of weights, each weight corresponding to a feature for which a feature-value is automatically generated from medical documents. These weights are used as multipliers, in certain implementations, of the feature values generated for a medical document. Multiplication of feature values by corresponding weights produces terms that are used to generate scores for each of various different E/M codes.

Abstract: The current document is directed to methods and systems for accessing, searching, analyzing, and visualizing electronically stored information, including electronic documents. These methods and systems construct graph-like representations of information searches that can be visualized and manipulated in three dimensions. The three-dimensional rendering of search results allows for very large numbers of search results to be visualized conveniently using a graphical user interface displayed on an electronic display device. Methods and systems provide for three-dimensional manipulation of graph-like renderings of search results, visualization-assisted searching, and a large number of research tools for discovering and storing various types of links, connections, and relationships between electronically stored information entities.