Abstract: Described herein are method of generating and uses of polypeptides with dual binding specificity, wherein the polypeptides contain a first binding-site for a first antigen and a second binding-site for a second antigen. The second binding-site comprises amino acid variants of native amino acid sequences of polypeptides that bind to the first antigen, wherein the variants do not abrogate binding to said first antigen. In one embodiment, polypeptides with dual binding specificity to PD1 and OX40 are disclosed herein. In another embodiment, polypeptides with dual binding specificity to PD1 and GITR are disclosed herein.

Abstract: Described herein are engineered anti-IL-2 antibodies with modified amino acid sequences. The engineered antibodies would confer modified receptor binding specificity to an IL-2-anti-IL2 antibody complex, inhibiting the binding of IL-2 to CD25. The engineered anti-IL-2 antibodies would facilitate expansion of subsets of effector immune cells and decrease undesirable effects caused by IL-2. Thus, the engineered anti-IL-2 antibodies would be useful in treating disease such as cancer and infection.

Abstract: Systems, methods and non-transitory computer readable media for controlling image acquisition robots in construction sites are provided. For example, a first image corresponding to a first point in time and a second image corresponding to a second point in time may be obtained. The first image and the second image may be analyzed to determine whether a change occurred in a particular area of a construction site between the first point in time and the second point in time. It may be determined whether a higher quality image of the particular area of the construction site is needed. An image acquisition robot may be controlled based on the determination of whether a change occurred in the particular area of the construction site and the determination of whether a higher quality image is needed.

Abstract: Systems and methods for generating assessments based on construction site images are provided. For example, image data captured from a construction site using at least one image sensor may be obtained. Further, at least one electronic record associated with the construction site may be obtained. The image data and the at least one electronic record may be analyzed to generate at least one assessment related to the construction site. For example, the image data may be analyzed to identify at least one discrepancy between the at least one electronic record and the construction site, and the identified at least one discrepancy may be used in the generation of the at least one assessment.

Abstract: Systems and methods for determining the quality of concrete from construction site images are provided. For example, image data captured from a construction site using at least one image sensor may be obtained. The image data may be analyzed to identify a region of the image data depicting at least part of an object, where the object is of an object type and made, at least partly, of concrete. The image data may be further analyzed to determine a quality indication associated with the concrete. The object type of the object may be used to select a threshold. The quality indication may be compared with the selected threshold. An indication to a user may be provided to a user based on a result of the comparison of the quality indication with the selected threshold.

Abstract: Systems and methods for hybrid processing of construction site images are provided. For example, image data captured from a construction site using at least one image sensor may be obtained. The image data may be analyzed to attempt to recognize an object depicted in the image data. In response to a failure to successfully recognize the object, at least part of the image data may be presented to a user, and a feedback related to the object may be received from the user. For example, the attempt to recognize an object may be based on a construction plan associated with the construction site, and the failure to successfully recognize the object may be identified based on a mismatch between the suggested object type from the attempt to recognize the object and types of objects selected from the construction plan based on the location of the object in the image data.

Abstract: Systems and methods for providing information on construction errors based on construction site images are provided. For example, image data captured from a construction site using at least one image sensor may be obtained. The image data may be analyzed to identify at least one construction error. Further, the image data may be analyzed to identify a type of the at least one construction error. In response to a first identified type of the at least one construction error, first information may be provided, and in response to a second identified type of the at least one construction error, providing the first information may be forgone.

Abstract: Systems, methods and non-transitory computer readable media for determining image capturing parameters in construction sites are provided. For example, a previously captured image of an object in a construction site may be accessed. The previously captured image of the object may be analyzed to determine at least one capturing parameter associated with the object for a prospective image capturing. Further, the systems, methods and non-transitory computer readable media may cause capturing, at the construction site, of at least one image of the object using the determined at least one capturing parameter associated with the object.

Abstract: Systems and methods for annotation of construction site images are provided. For example, image data captured from a construction site using at least one image sensor may be obtained. Further, at least one construction plan associated with the construction site and including information related to an object may be obtained. The at least one construction plan may be analyzed to identify a first region of the image data corresponding to the object. The at least one display device may be used to present at least part of the image data to a user with an indication of the identified first region of the image data corresponding to the object. Further, the at least one display device may be used to present to the user a query related to the object. A response to the query may be received from the user. The response may be used to update information associated with the object in at least one electronic record associated with the construction site.

Abstract: Systems and methods for providing information on construction errors based on construction site images are provided. For example, image data captured from a construction site using at least one image sensor may be obtained. The image data may be analyzed to identify at least one construction error. Further, the image data may be analyzed to identify a type of the at least one construction error. In response to a first identified type of the at least one construction error, first information may be provided, and in response to a second identified type of the at least one construction error, providing the first information may be forgone.

Abstract: Systems and methods for providing information based on construction site images are provided. For example, image data captured from a construction site using at least one image sensor may be obtained. Further, at least one electronic record associated with the construction site may be obtained. The image data may be analyzed to identify at least one discrepancy between the at least one electronic record and the construction site. Further, information based on the identified at least one discrepancy may be provided to a user.

Abstract: Systems and methods for updating records based on construction site images are provided. For example, image data captured from a construction site using at least one image sensor may be obtained. The image data may be analyzed to detect at least one object in the construction site. Further, at least one electronic record associated with the construction site may be updated based on the detected at least one object. In some examples, the at least one electronic record may comprise a searchable database, and updating the at least one electronic record may comprise indexing the at least one object in the searchable database.

Abstract: Systems and methods for hybrid processing of construction site images are provided. For example, image data captured from a construction site using at least one image sensor may be obtained. The image data may be analyzed to attempt to recognize an object depicted in the image data. In response to a failure to successfully recognize the object, at least part of the image data may be presented to a user, and a feedback related to the object may be received from the user. For example, the attempt to recognize an object may be based on a construction plan associated with the construction site, and the failure to successfully recognize the object may be identified based on a mismatch between the suggested object type from the attempt to recognize the object and types of objects selected from the construction plan based on the location of the object in the image data.

Abstract: Systems and methods for generating financial assessments based on construction site images are provided. For example, image data captured from a construction site using at least one image sensor may be obtained. Further, at least one electronic record associated with the construction site may be obtained. The image data and the at least one electronic record may be analyzed to generate at least one financial assessment related to the construction site. For example, the image data may be analyzed to identify at least one discrepancy between the at least one electronic record and the construction site, and the identified at least one discrepancy may be used in the generation of the at least one financial assessment.

Abstract: Systems and methods for ranking entities using construction site images are provided. For example, image data captured from a construction site using at least one image sensor may be obtained. The image data may be analyzed to detect at least one element depicted in the image data and associated with an entity. The image data may be further analyzed to determine at least one property indicative of quality and associated with the at least one element. The at least one property may be used to generate a ranking of the entity. In some examples, the at least one property may be based on a discrepancy between a construction plan and the construction site, between a project schedule and the construction site, between a financial record and the construction site, between a progress record and the construction site, and so forth.

Abstract: Systems and methods for annotation of construction site images are provided. For example, image data captured from a construction site using at least one image sensor may be obtained. Further, at least one construction plan associated with the construction site and including information related to an object may be obtained. The at least one construction plan may be analyzed to identify a first region of the image data corresponding to the object. The at least one display device may be used to present at least part of the image data to a user with an indication of the identified first region of the image data corresponding to the object. Further, the at least one display device may be used to present to the user a query related to the object. A response to the query may be received from the user. The response may be used to update information associated with the object in at least one electronic record associated with the construction site.

Abstract: Systems and methods for providing information based on construction site images are provided. For example, image data captured from a construction site using at least one image sensor may be obtained. Further, at least one electronic record associated with the construction site may be obtained. The image data may be analyzed to identify at least one discrepancy between the at least one electronic record and the construction site. Further, information based on the identified at least one discrepancy may be provided to a user.

Abstract: Systems and methods for determining the quality of concrete from construction site images are provided. For example, image data captured from a construction site using at least one image sensor may be obtained. The image data may be analyzed to identify a region of the image data depicting at least part of an object, where the object is of an object type and made, at least partly, of concrete. The image data may be further analyzed to determine a quality indication associated with the concrete. The object type of the object may be used to select a threshold. The quality indication may be compared with the selected threshold. An indication to a user may be provided to a user based on a result of the comparison of the quality indication with the selected threshold.

Abstract: System and method for processing images of concrete are provided. Image data captured from a construction site may be obtained. The image data may be analyzed to identify regions of the image data that depict concrete. The image data may be analyzed to determine quality indications associated with concrete depicted in the image data, for example in a region identified above. In some examples, the quality indications may comprise an indication of the durability of the concrete, of the strength of the concrete, and so forth.

Abstract: System and method for processing images of concrete are provided. Image data captured from a construction site may be obtained. The image data may be analyzed to identify regions of the image data that depict concrete. The image data may be analyzed to determine quality indications associated with concrete depicted in the image data, for example in a region identified above. In some examples, the quality indications may comprise an indication of the durability of the concrete, of the strength of the concrete, and so forth.