Abstract: The present disclosure relates to a sensor for measuring at least one physical or chemical parameter of a cartridge or syringe filled with a liquid substance. In further aspects, the disclosure relates to a cartridge equipped with such a sensor as well as to a drug delivery device equipped with such a cartridge, wherein the sensor comprises: a planar flexible foil arrangeable to an outer circumference of a barrel of the cartridge or syringe, at least a first and a second measuring electrode arranged on said foil, at least a first and a second contact electrode arranged on said foil, and a processor arranged on said foil and connected to the first and to the second measuring electrodes, wherein the first contact electrode and the second contact electrode are connected to the processor.

Abstract: In one aspect the present disclosure relates to a sensor for measuring at least one physical or chemical parameter of a cartridge or syringe filled with a liquid substance. In further aspects the disclosure relates to a cartridge equipped with such a sensor as well as to a drug delivery device equipped with such a cartridge, wherein the sensor comprises: a planar flexible foil arrangeable to an outer circumference of a barrel of the cartridge or syringe, at least a first and a second measuring electrode arranged on said foil, and at least a first and a second contact electrode arranged on said foil, wherein the first contact electrode is connected to the first measuring electrode and wherein the second contact electrode is connected to the second measuring electrode.

Abstract: A data collection device comprises an attachment assembly for attaching the data collection device to a dose setting dial of a medicament administration device and a sensor configured to detected an identifier provided on a surface of an internal component of the medicament administration device, the sensor comprising an ultrasound sensor configured to detect a geometric identifier formed on the surface of the internal component of the medicament administration device. A system comprises the data collection device and the medicament administration device.

Abstract: A drug delivery device is provided comprising a container, a first product and a second product. The device is configured to mix the first product and the second product with each other within the container for forming a drug mixture. The device is further configured for dispensing the drug mixture. The device comprises a mixing member. The device is switchable from a first state, in which the first product and the second product are separated, into a second state, in which the first product and the second product are mixed. The mixing member is configured to exert a force onto the container in order to move the container to mix the first product and the second product with each other. Furthermore, a method for maintaining a predetermined property of a drug mixture to be dispensed from a drug delivery device is provided.

Abstract: The present disclosure relates to a dosage measurement system for a medicament delivery device. The medicament delivery device comprises a medicament reservoir, a lead screw and a drive sleeve. The drive sleeve is rotatable to axially displace the lead screw relative to the drive sleeve to dispense medicament from the medicament reservoir. The dosage measurement system comprises a sensor unit and a processor. The sensor unit is configured to measure rotation of at least one of the drive sleeve and lead screw. The processor is configured to determine a dosage dispensed from the medicament reservoir based on the measured rotation of said at least one of the drive sleeve and lead screw.

Abstract: A reservoir for liquid medicament includes a first boundary portion and a second boundary portion forming at least one cavity to receive the medicament. The first boundary portion is flexible, while the second boundary portion is rigid. At least one of the first and second boundary portions is a transparent boundary portion covered by an opaque cover which is at least partially detachable from the transparent boundary portion.

Abstract: Systems and methods for mixing and/or reconstituting drugs are presented. A system may include an injection device, a vial, a needle, and a base station. The device has a chamber containing a first material. The vial has a chamber containing a second material. A drive unit of the base station moves the vial and/or the housing of the device relative to each other into an activated position. In the activated position, the needle is fluidly connected with the vial's chamber, and the drive unit is connected to a driver that moves the plunger in the axial direction of the device such that during fluid connection of the needle with the vial's chamber the first material is expelled from the device's chamber into the vial's chamber or the second material is expelled from the vial's chamber into the device's chamber.

Abstract: The present disclosure relates to medicament injection devices. An injection device includes: a movable dosage programming component comprising a rotary encoder system having a predefined angular periodicity, a sensor arrangement including a first optical sensor configured to detect movement of the movable dosage programming component relative to the sensor arrangement during dosing of a medicament, wherein the first optical sensor is configured to operate in a strobe-sampling mode at a first frequency, a second optical sensor configured to detect movement of the rotary encoder system relative to the second optical sensor wherein the second optical sensor is configured to operate in a strobe-sampling mode at a second frequency lower than the first frequency, and a processor arrangement configured to, based on the detected movement, determine a medicament dosage administered by the injection device.

Abstract: A portable medical memory device includes a battery; a non-volatile memory; and a near field communication transceiver. The device is configured to: transfer power from the battery to a medical device via the near field communication transceiver to trigger a measurement by a sensor of the medical device; read sensor data obtained by the measurement from the medical device using the near field communication transceiver; and store the sensor data in the non-volatile memory.

Abstract: Implementations of the present disclosure are directed to an injection device (102) that includes a medicament reservoir (103), a stopper (105) including a rigid core (125) and an ultrasound probe (122) disposed in a housing, the ultrasound probe configured to transmit an emitted ultrasound signal through the rigid core along a longitudinal direction of the rigid core into the medicament reservoir and to receive an ultrasound signal generated by reflections of the emitted ultrasound signal, the reflections including at least a reflection from a distal end of the medicament reservoir, a control component (124a) configured to be electronically coupled with the ultrasound probe and to process the ultrasound signal to generate injection device data, and an antenna (124c) configured to be electronically coupled with the control component and to transmit the injection device data to an external computing device (104).

Abstract: A mixing and/or reconstitution system reduces the possibility of user error and provides a well mixed and/or reconstituted drug in a short time. The system comprises a device containing a first material within a first chamber, a housing, and a plunger, the plunger comprising a second chamber containing a second material, wherein one of the first and the second material is a fluid, and a movable element with an electric, magnetic, or paramagnetic characteristic, wherein the second chamber is initially closed; and a base unit comprising a recess for accommodation of the device, a control unit, and an electromagnetic unit which is adapted to produce an electromagnetic field penetrating the recess, wherein the control unit can electrically operate the electromagnetic unit such that the element contained in the second chamber moves in a direction of the device determined by the electromagnetic field and fluidly communicates the first and second chambers.

Abstract: An injection device for setting and injecting a dose of a medicament comprises an elongated housing extending along a longitudinal axis, a piston rod to operably engage with a piston of a cartridge filled with the medicament, a clutch comprising a hollow interior and configured to be rotated in a first direction relative to the housing during setting of a dose and to be rotated in a second direction relative to the housing during delivery of the dosea driver configured to follow a rotational movement of the clutch in the second direction during delivery of the dose, the piston rod being operably engaged with the driver and configured to be displaced along the longitudinal axis relative to the housing when the driver rotates in the second direction, and a retainer configured to prevent a rotational movement of the driver relative to the housing in the first direction during setting of the dose.

Abstract: An apparatus for detecting activation of a drug delivery device using a passive sensor. The passive sensor is configured to detect vibration of a drug delivery device caused by programming of a dose of medicament into the drug delivery device. The apparatus uses an output signal generated by the passive sensor in response to the vibration to provide a wake-up input signal to an electronic dose monitoring unit for monitoring the drug delivery device.

Abstract: The disclosure relates to a medicament delivery device, comprising a medicament cartridge adapted to contain a medicament and a stopper slidably arranged within the cartridge. The stopper-comprises a rigid body that is enclosed partially by a soft sealing component.

Abstract: The present disclosure relates to a bolus calculator for determining a bolus of insulin, the bolus calculator having an input configured to be fed with a time series (h(t-t)) of blood glucose values and to store at least one known pulse response (x(T)) representing an active profile of at least one insulin, wherein the bolus calculator is configured to convolute the time series (h(t-T)) of blood glucose values with the known pulse response (x(T)) to obtain the bolus and to a method for calculating a bolus of insulin, comprising feeding a time series (h(t-T)) of blood glucose values into an input of a bolus calculator and storing at least one known pulse response (x(T)) representing an active profile of at least one insulin in the bolus calculator, convoluting the time series (h(t-T)) of blood glucose values with the known pulse response (x(T)) to obtain the bolus.

Abstract: The disclosure refers to a device, for example a cartridge, a syringe or an autoinjector, which reduces the possibility of user error and provides an easy and automatic operation during mixing and/or reconstitution. The device is adapted such that activation of the device causes movement one of a first piston and a second piston in second chamber in an axial direction of the device, thereby moving the other one of the first piston and the second piston into the same axial direction of the device, opening a fluid communication path between the second chamber and a first chamber of the device, and expelling a second material from the second chamber into the first chamber via the fluid communication path. The disclosure is further directed to a respective mixing and/or reconstitution method.

Abstract: An injection device includes an elongated housing extending along a longitudinal axis, a piston rod to operably engage with a piston of a cartridge filled with the medicament, a dose tracker selectively operably engageable with the piston rod, wherein the dose tracker is longitudinally displaceable relative to the housing from an initial position in a proximal direction towards at least a first activation position for setting of the dose and wherein the dose tracker is longitudinally displaceable relative to the housing in a distal direction from the at least first activation position towards the initial position for dispensing of the dose, a spring to urge the dose tracker in the proximal direction relative to the housing, an interlock to lock the dose tracker in the initial position relative to the housing, and a release member to release the interlock.

Abstract: A stopper is disclosed herein. The stopper is configured to be disposed within a medical cartridge. The stopper includes a shell defining a cavity, a core arranged within the cavity, and at least one electronic device embedded within the core, wherein the at least one electronic device includes a sensor and wherein the shell is configured to pass a sensing signal therethrough.

Abstract: An injection device includes a cartridge configured to hold a volume of fluid, the cartridge having a proximal end and a distal end through which the fluid is dispensed; a stopper disposed in the cartridge and configured to move from the proximal end toward the distal end to cause the fluid to be dispensed through the distal end of the cartridge; and an electronic device disposed at the distal end of the cartridge, the electronic device including an emitter configured to transmit a signal toward the stopper, a receiver configured to receive reflections of the signal from the stopper, and a controller configured to wirelessly transmit data related to a position of the stopper in the cartridge.

Abstract: The disclosure relates to a drug delivery device including at least a housing, a drug container with a needle, and a cap, wherein the housing has an inner surface forming a cavity configured to retain the drug container, wherein the cap is configured to be releasably connected to the housing, and wherein a back end of the device opposite to a front end of the device directed to the cap includes a gripping lug axially protruding from the back end of the device. The disclosure further relates to an emergency pack including such a drug delivery device.