Abstract: Described herein are cyclic peptides targeting human epidermal growth factor receptor 2 (HER2), and their incorporation into compounds for radioligand imaging and therapies, as well as methods and/or uses of such compounds for the imaging, treatment and/or prevention of HER2-implicated diseases and disorders (e.g., cancer).

Abstract: A hydraulic drive system for a construction and/or thick matter pump system includes a first drive cylinder and a second drive cylinder, a first directional valve and a second directional valve, and a flushing hydraulic liquid device. The first directional valve is configured to connect the first drive cylinder to the second directional valve by way of a first switching position and to connect the second directional valve to the flushing hydraulic liquid device by way of a second switching position. The second directional valve is configured to connect the second drive cylinder to the first directional valve by way of a first switching position and to connect the first directional valve to the flushing hydraulic liquid device by way of a second switching position.

Abstract: A hydraulic drive system for a construction and/or thick matter pump system includes a first drive cylinder and a second drive cylinder, a first directional valve and a second directional valve, and a flushing hydraulic liquid device. The first directional valve is configured to connect the first drive cylinder to the second directional valve by way of a first switching position and to connect the second directional valve to the flushing hydraulic liquid device by way of a second switching position. The second directional valve is configured to connect the second drive cylinder to the first directional valve by way of a first switching position and to connect the first directional valve to the flushing hydraulic liquid device by way of a second switching position.

Abstract: Techniques for encoding/decoding of video signals are described, e.g. implemented in decoders, encoder, methods and non-transitory storage units storing instructions to perform the methods. A decoder or encoder may be configured to predict a predetermined block of the picture using a plurality of neighbouring samples by reducing the plurality of neighbouring samples to obtain a reduced set of samples values lower, in number of samples, than compared to the plurality of neighbouring samples, subjecting the reduced set of sample values to a linear or affine linear transformation to obtain predicted values for predetermined samples of the predetermined block.

Abstract: Apparatus configured to derive a set-selective syntax element indicating whether the predetermined block is to be predicted using one of a first set of intra-prediction modes comprising a DC intra prediction mode and angular prediction modes. If the set-selective syntax element indicates that the predetermined block is to be predicted using one of the first set of intra-prediction modes, the apparatus is configured to use a list of most probable intra-prediction modes. If the set-selective syntax element indicates that the predetermined block is not to be predicted using one of the first set of intra-prediction modes, the apparatus is configured to use a matrix-based intra-prediction mode. The list of most probable intra-prediction modes is formed such that the list of most probable intra-prediction modes is free of the DC intra prediction mode in case of the neighbouring blocks being predicted by any of the angular intra prediction modes.

Abstract: Techniques for encoding/decoding of video signals are described, e.g. implemented in decoders, encoder, methods and non-transitory storage units storing instructions to perform the methods. A decoder or encoder may be configured to predict a predetermined block of the picture using a plurality of neighbouring samples by reducing the plurality of neighbouring samples to obtain a reduced set of samples values lower, in number of samples, than compared to the plurality of neighbouring samples, subjecting the reduced set of sample values to a linear or affine linear transformation to obtain predicted values for predetermined samples of the predetermined block.

Abstract: Apparatus configured to derive a set-selective syntax element indicating whether the predetermined block is to be predicted using one of a first set of intra-prediction modes comprising a DC intra prediction mode and angular prediction modes. If the set-selective syntax element indicates that the predetermined block is to be predicted using one of the first set of intra-prediction modes, the apparatus is configured to use a list of most probable intra-prediction modes. If the set-selective syntax element indicates that the predetermined block is not to be predicted using one of the first set of intra-prediction modes, the apparatus is configured to use a matrix-based intra-prediction mode. The list of most probable intra-prediction modes is formed such that the list of most probable intra-prediction modes is free of the DC intra prediction mode in case of the neighbouring blocks being predicted by any of the angular intra prediction modes.

Abstract: An electric parking brake (100) has a spindle drive (28) which is electrically actuable and self-locking. The spindle drive (28) comprise a spindle (34) with an external thread and a spindle nut (30) with an internal thread which is in engagement with the external thread. Here, the external thread and the internal thread have a symmetrical thread profile. Furthermore, the profile edges of adjacent profile crests of the external thread merge directly into one another via a rounded portion in the profile trough which lies in between. Furthermore, a method for producing a parking brake (100) of this type is provided.

Abstract: An apparatus for conveying thick matter has a drive cylinder for receiving hydraulic fluid, a drive piston, which is arranged in the drive cylinder, a conveying cylinder for receiving thick matter, a conveying piston, which is arranged in the conveying cylinder, and a piston rod, which is fastened to the drive piston for coupling motion together with the conveying piston. The drive cylinder has a rod-side opening for applying pressure to a rod side of the drive piston by way of hydraulic fluid and a crown-side opening for applying pressure to a crown side of the drive piston facing away from the rod side by the hydraulic fluid. A drive pump is designed to generate a drive volume flow having a drive pressure of hydraulic fluid for moving the drive piston. A pump connection is designed for variable connection of the drive pump to the rod-side opening or the crown-side opening for the flow of hydraulic fluid.

Abstract: A method monitors the state of a device having a first drive cylinder for receiving hydraulic fluid and a first drive piston which is movably arranged in the first drive cylinder. The method determines a speed of the first drive piston, establishes a difference between the determined speed of the first drive piston and an expected speed of the first drive piston, and determines a faulty state as a function of the difference established between the determined speed of the first drive piston and the expected speed of the first drive piston.

Abstract: A system and method are disclosed for monitoring rides in a vehicle in which a driver of the vehicle picks up a rider at a pickup location and drives the rider to a drop-off destination. The system includes at least one sensor arranged in the vehicle and configured to capture sensor data during the rides, a transceiver configured to communicate with a personal electronic device of a driver of the vehicle, a non-volatile memory configured to store data; and a processor. The system captures sensor data during a ride, receives a ride identifier from the personal electronic device that uniquely identifies the ride, and stores the sensor data captured during the ride with the ride identifier as metadata.

Abstract: A control circuitry (11) comprises an adjustable capacitor (C1), and a bias source (111) configured to apply a bias voltage (V2) to said adjustable capacitor (C1) to adjust a capacitance value of the adjustable capacitor (C1). Such a control circuitry may for example be part of a sealing device (1) to seal a medical tubing (2), the sealing device (1) comprising a receptacle (100) to receive said medical tubing (2), the receptacle (100) comprising an electrode arrangement for causing a heat action on the tubing (2).

Abstract: A laser activatable polymer composition is provided. The composition contains a polymer matrix that includes at least one polyarylene sulfide and at least one condensation polymer; at least one laser activatable additive; and inorganic fibers. The polymer composition exhibits a dielectric constant of about 5 or less at a frequency of 2 GHz, a flexural modulus of about 13,500 MPa or more as determined at a temperature of 23° C. in accordance with ISO 178:2019, and a deflection temperature under load of about 260° C. or more as determined in accordance with ISO 75:2013 at a load of 1.8 MPa.

Abstract: Apparatus (54) for decoding a predetermined block (18) of a picture using intra-prediction, configured to read, from a data stream (12), a mode index (200) using a binarization code (202). The mode index (200) points to one out of a list (204) of matrix-based intra-prediction modes. The apparatus is configured to predict samples (108) of the predetermined block (18) by computing a matrix-vector product (206) between an input vector (102) derived from reference samples (17) in a neighbourhood of the predetermined block (18) and a prediction matrix (19) associated with the matrix-based intra-prediction mode (k) pointed to by the mode index (200) and associating components (210) of an output vector (208) obtained by the matrix-vector product (206) onto sample positions (104) of the predetermined block. The list (204) of matrix-based intra-prediction modes consists of an even number of matrix-based intra-prediction modes.

Abstract: A TIRFM-capable microscope including: a light source that generates/emits incoherent excitation light onto an optical path that includes a first projection lens system, a spatial filter, a second projection lens system and an objective. The TIRFM-capable microscope also includes a controller; wherein the first projection lens system projects excitation light onto the spatial filter that filters the excitation light with two-dimensional patterns, the spatial filter lies in a plane conjugate to a back focal plane of the objective which includes an objective lens that directs excitation light onto and receives fluorescent light from the sample, wherein, for a numerical aperture NAObj of the objective and a refractive index nspec of the sample NAObj>nspec, and the controller activates the spatial filter to select/generate various two-dimensional patterns and selects/adjusts the position/shape/size of the pattern such that TIRF illumination of the sample is generated.

Abstract: A method operates a construction material and/or viscous-material pump having: at least one conveying cylinder, the conveying cylinder being designed to receive and discharge construction material and/or viscous material; and at least one conveying piston, the conveying piston being disposed in the conveying cylinder for movement in order to draw construction material and/or viscous material into the conveying cylinder and to displace drawn-in construction material and/or viscous material out of the conveying cylinder.

Abstract: The present disclosure relates to a Bulk Acoustic Wave (BAW) resonator, which includes a bottom electrode, a top electrode structure, and a multilayer transduction structure sandwiched therebetween. Herein, the multilayer transduction structure is composed of multiple transduction layers, at least one of which is formed of a ferroelectric material with a box-shape polarization-electric field curve. Each transduction layer includes a transduction border (BO) portion positioned at a periphery of a corresponding transduction layer and a transduction central portion surrounded by the transduction BO portion. A combination of all transduction BO portions forms a transduction BO section of the multilayer transduction structure, and a combination of all transduction central portions forms a transduction central section of the multilayer transduction structure.

Abstract: This invention relates a wax inhibitor for hydrocarbon oils comprising an esterified copolymer having repeating structural units derived from an esterified ethylenically unsaturated dicarboxylic acid and ?-olefins having at least 18 carbon atoms, whereof at least 3 mol-% of the ?-olefins have 30 or more carbon atoms, and wherein the ethylenically unsaturated dicarboxylic acid has been esterified with a mixture of alcohols comprising i) 70 to 97 mol-% of a saturated fatty alcohol having 18 to 24 carbon atoms and ii) 3 to 30 mol-% of an unsaturated alcohol having 16 to 24 carbon atoms.

Abstract: An apparatus, kit, and method for rehabilitating and/or strengthening the soft tissues of a user's lower arm is disclosed. The apparatus has a first arm with a proximal end and a distal end; a second arm with a proximal end, a distal end, one or more discrete sections therebetween for engaging one or more weights, and a means for providing an audible feedback to the user upon completion of an exercise repetition or a half-repetition; and a hinge in contact with the proximal ends of the first and second arms. The hinge is configured to adjust the distance between the distal ends of the first and second arms, or the angle separating the first and second arms.

Abstract: Techniques for encoding/decoding of video signals are described, e.g. implemented in decoders, encoder, methods and non-transitory storage units storing instructions to perform the methods. A decoder or encoder may be configured to predict a predetermined block of the picture using a plurality of neighbouring samples by reducing the plurality of neighbouring samples to obtain a reduced set of samples values lower, in number of samples, than compared to the plurality of neighbouring samples, subjecting the reduced set of sample values to a linear or affine linear transformation to obtain predicted values for predetermined samples of the predetermined block.