Abstract: The invention relates to a hydroxycarboxylic acid of the formula CH3(CH2)8 CHOH—(CH2)—CO2H or a pharmaceutically acceptable salt thereof, for use as a medicament, particularly for use in the treatment or prevention, including prevention of recurrence, of cancer, for example colorectal cancer. The invention further relates to a combination medicament for use in the treatment or the prevention of recurrence of cancer comprising a hydroxycarboxylic acid as specified herein, and another antineoplastic treatment. Further aspects of the invention relate to a method of measuring the presence of a hydroxydicarboxylic acid of the formula HO2C(CH2)7 CH2CHOH—(CH2)—CO2H, or CH3(CH2)10COOH to predict or to monitor the clinical outcome of a cancer patient, and/or to predict or monitor the response to an antineoplastic therapy or treatment with live bacteria.

Abstract: The invention provides a bacterial composition comprising, or consisting of, one or more of the genera of bacteria selected from Anaerostipes, and/or Roseburia, for treatment, or for prevention of recurrence, of cancer. In another aspect, the invention relates to a combination medicament for use in the treatment or the prevention of recurrence of cancer comprising a bacterial composition as specified herein and an antineoplastic treatment, particularly a combination medicament comprising a bacterial composition and a cancer chemotherapy drug, or a bacterial composition as provided herein and a cancer immunotherapy drug.

Abstract: The invention relates to a method for diagnosis of colorectal carcinoma in a patient, including detecting, in a blood sample obtained from said patient, an indicator protein selected from integrin subunit alpha(v) and integrin subunit beta(6) or their heterodimer.

Abstract: The invention relates to a method for diagnosis of colorectal carcinoma in a patient, comprising detecting, in a blood sample obtained from said patient, an indicator protein selected from the group comprised of integrin subunit alpha (v) and integrin subunit beta (6) or their heterodimer.

Abstract: This invention is in the field of Crohn's disease. In particular, it relates to the treatment of fistulas in Crohn's disease using anti-IL-13 antibodies. The antibody may be an IgG and in particular may be the anti-IL-13 antibody 01951/G12.