Patents by Inventor Michael SCHEBESTA

Michael SCHEBESTA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CA2 COMPOSITIONS AND METHODS FOR TUNABLE REGULATION
    Publication number: 20230026259
    Abstract: The present disclosure provides regulatable biocircuit systems. Such systems provide modular and tunable protein expression systems in support of the discovery and development of therapeutic modalities. In particular, the present application is directed to fusion proteins comprising a fragment of human human carbonic anhydrase 2 and a chimeric antigen receptor (CAR). The activity of the destabilizing domain can be regulated by externally administered agents.
    Type: Application
    Filed: March 6, 2020
    Publication date: January 26, 2023
    Applicant: Obsidian Therapeutics, Inc.
    Inventors: Vipin SURI, Celeste RICHARDSON, Brian DOLINSKI, Abhishek KULKARNI, Mara Christine Inniss, Dexue SUN, Elizabeth Jane WEISMAN, Grace Y. Olinger, Scott Francis HELLER, Jennifer Leah GORI, Michelle Lynn OLS, Kutlu Goksu ELPEK, Tucker Read EZELL, Michael SCHEBESTA, Michelle Lois FLEURY, Dhruv Kam SETHI
  • CA2 COMPOSITIONS AND METHODS FOR TUNABLE REGULATION
    Publication number: 20220267398
    Abstract: The present disclosure provides regulatable biocircuit systems. Such systems provide modular and tunable protein expression systems in support of the discovery and development of therapeutic modalities.
    Type: Application
    Filed: June 12, 2020
    Publication date: August 25, 2022
    Inventors: Michelle Lynn OLS, Vipin SURI, Dexue SUN, Dhruv Kam SETHI, Michael SCHEBESTA, Michelle Lois FLEURY, Kutlu Goksu ELPEK
  • CA2 COMPOSITIONS AND METHODS FOR TUNABLE REGULATION
    Publication number: 20220259284
    Abstract: The present disclosure provides regulatable biocircuit systems. Such systems provide modular and tunable protein expression systems in support of the discovery and development of therapeutic modalities.
    Type: Application
    Filed: June 12, 2020
    Publication date: August 18, 2022
    Inventors: Michael SCHEBESTA, Michelle Lois FLEURY, Kutlu Goksu ELPEK
  • CD40L COMPOSITIONS AND METHODS FOR TUNABLE REGULATION
    Publication number: 20220175781
    Abstract: The present disclosure provides regulatable biocircuit systems, effector modules and compositions for cancer immunotherapy. Methods for inducing anti-cancer immune responses in a subject are also provided.
    Type: Application
    Filed: March 6, 2020
    Publication date: June 9, 2022
    Applicant: Obsidian Therapeutics, Inc.
    Inventors: Michael SCHEBESTA, Michelle Lois FLEURY, Kutlu Goksu ELPEK, Elizabeth Jane WEISMAN, Vipin SURI, Dexue SUN, Dan Jun LI, Steven Mark SHAMAH, Michael Joseph BRISKIN, Celeste RICHARDSON, Tariq A. KASSUM, Michelle Lynn OLS, Brian DOLINSKI, Mara Christine INNISS, Emily BRIDEAU, Jennifer Leah GORI, Dhruv Kam SETHI
  • ER TUNABLE PROTEIN REGULATION
    Publication number: 20210386788
    Abstract: The present disclosure is related to compositions and methods for the regulated and controlled expression of proteins.
    Type: Application
    Filed: October 23, 2019
    Publication date: December 16, 2021
    Applicant: Obsidian Therapeutics, Inc.
    Inventors: Vipin SURI, Dexue SUN, Michelle Lynn OLS, Scott Francis HELLER, Dan Jun LI, Celeste RICHARDSON, Mara Christine INNISS, Jennifer Leah GORI, Benjamin J. PRIMACK, Abhishek KULKARNI, Brian DOLINSKI, Tucker Read EZELL, Michael SCHEBESTA, James A. STORER, Kutlu Goksu ELPEK