Patents by Inventor Michael Scherz

Michael Scherz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thiazolidin 4-one derivatives
    Patent number: 8273779
    Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: September 25, 2012
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Christoph Binkert, Martin Bolli, Boris Mathys, Claus Mueller, Michael Scherz, Oliver Nayler
  • DOSING REGIMEN FOR A SELECTIVE S1P1 RECEPTOR AGONIST
    Publication number: 20110021581
    Abstract: The present invention relates to a dosing regimen for a selective S1P1 receptor agonist, whereby the selective S1P1 receptor agonist is administered to a subject in such a way that during the initial treatment phase the selective S1P1 receptor agonist is administered at a dose which induces desensitization of the heart wherein said dose is below the target dose, and at a dosing frequency that sustains desensitization of the heart, until no further acute heart rate reduction occurs, followed by dose up-titration to the target dose of the selective S1P1 receptor agonist.
    Type: Application
    Filed: March 12, 2009
    Publication date: January 27, 2011
    Applicant: ACTELION PHARMACEUTICALS LTD
    Inventors: Patrick Brossard, Jasper Dingemanse, Oliver Nayler, Michael Scherz, Beat Steiner
  • Thiazolidin-4-one derivatives
    Patent number: 7875726
    Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.
    Type: Grant
    Filed: June 3, 2008
    Date of Patent: January 25, 2011
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Christoph Binkert, Martin Bolli, Boris Mathys, Claus Mueller, Michael Scherz, Oliver Nayler
  • Pyridine derivatives
    Patent number: 7750161
    Abstract: The invention relates to novel pyridine derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Grant
    Filed: September 21, 2004
    Date of Patent: July 6, 2010
    Inventors: Daniel Bur, Martine Clozel, Boris Mathys, Claus Mueller, Michael Scherz, Joerg Velker, Thomas Weller
  • Thiophene derivatives
    Patent number: 7750040
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Grant
    Filed: July 20, 2005
    Date of Patent: July 6, 2010
    Inventors: Martin Bolli, Daniel Bur, Martine Clozel, Walter Fischli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Thomas Weller
  • Thiazolidin-4-one derivatives
    Patent number: 7626037
    Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.
    Type: Grant
    Filed: February 5, 2008
    Date of Patent: December 1, 2009
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Christoph Binkert, Martin Bolli, Boris Mathys, Claus Mueller, Michael Scherz, Oliver Nayler
  • NOVEL THIAZOLIDIN 4-ONE DERIVATIVES
    Publication number: 20090275625
    Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.
    Type: Application
    Filed: July 2, 2009
    Publication date: November 5, 2009
    Inventors: Christoph Binkert, Martin Bolli, Boris Mathys, Claus Mueller, Michael Scherz, Oliver Nayler
  • NOVEL THIAZOLIDIN-4-ONE DERIVATIVES
    Publication number: 20080280962
    Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.
    Type: Application
    Filed: June 3, 2008
    Publication date: November 13, 2008
    Applicant: ACTELION PHARMACEUTICALS, LTD.
    Inventors: Christoph Binkert, Martin Bolli, Boris Mathys, Claus Mueller, Michael Scherz, Oliver Nayler
  • Thiazolidin-4-one derivatives
    Patent number: 7435828
    Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4- one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.
    Type: Grant
    Filed: November 16, 2004
    Date of Patent: October 14, 2008
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Christoph Binkert, Martin Bolli, Boris Mathys, Claus Mueller, Michael Scherz, Oliver Nayler
  • NOVEL THIAZOLIDIN-4-ONE DERIVATIVES
    Publication number: 20080146629
    Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.
    Type: Application
    Filed: February 5, 2008
    Publication date: June 19, 2008
    Applicant: ACTELION PHARMACEUTICALS, LTD.
    Inventors: Christoph Binkert, Martin Bolli, Boris Mathys, Claus Mueller, Michael Scherz, Oliver Nayler
  • Quinoline derivatives
    Patent number: 7375227
    Abstract: The invention relates to novel 1-pyridin-4-yl urea derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Grant
    Filed: December 2, 2002
    Date of Patent: May 20, 2008
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Jörg Velker, Thomas Weller
  • Novel Thiophene Derivatives
    Publication number: 20080064740
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Application
    Filed: July 20, 2005
    Publication date: March 13, 2008
    Applicant: ACTELION PHARMACEUTICALS, LTD.
    Inventors: Martin Bolli, Daniel Bur, Martine Clozel, Walter Fischli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Thomas Weller
  • Novel thiazolidin-4-one derivatives
    Publication number: 20070082933
    Abstract: The invention relates to pharmaceutical compositions containing at least one thiazolidin-4-one derivative to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thiazolidin-4-one derivatives notably for use as pharmaceutically active compounds. Said compounds particularly act also as immunosuppressive agents.
    Type: Application
    Filed: November 16, 2004
    Publication date: April 12, 2007
    Inventors: Christoph Binkert, Martin Bolli, Boris Mathys, Claus Mueller, Michael Scherz
  • Novel pyridine derivatives
    Publication number: 20070043081
    Abstract: The invention relates to novel pyridine derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Application
    Filed: September 21, 2004
    Publication date: February 22, 2007
    Inventors: Daniel Bur, Martine Clozel, Boris Mathys, Claus Mueller, Michael Scherz, Joerg Velker, Thomas Weller
  • Novel piperidine derivatives
    Publication number: 20070010516
    Abstract: The invention relates to novel piperidine derivatives and related compounds of General Formula I and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists, in particular their use as urotensin II antagonists.
    Type: Application
    Filed: May 4, 2004
    Publication date: January 11, 2007
    Inventors: Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Jorg Velker, Thomas Weller
  • Piperazine-alkyl-ureido derivatives
    Publication number: 20060211707
    Abstract: The invention relates to novel piperazine derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Application
    Filed: May 4, 2004
    Publication date: September 21, 2006
    Inventors: Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Jorg Velker, Thomas Weller
  • 1-Pyridin-4-yl-urea derivatives
    Publication number: 20060094716
    Abstract: The invention relates to novel 1-pyridin-4-yl urea derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Application
    Filed: September 12, 2003
    Publication date: May 4, 2006
    Applicant: Actelion Pharmaceuticals LTD
    Inventors: Hamed Aissaoui, Christoph Binkert, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Thomas Weller, Jorg Welker, Martine Clozel
  • 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea salt
    Publication number: 20060079552
    Abstract: The invention relates to 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea as a crystalline salt or a non defined salt hydrate thereof and a process for its preparation. Further, the present invention relates to the use of said 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea as a crystalline salt alone or in combination with other compounds or formulations of said 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea as a crystalline salt in the preparation of pharmaceutical compositions. The invention also relates to the use of such salts in formulations as neurohormonal antagonists.
    Type: Application
    Filed: October 12, 2004
    Publication date: April 13, 2006
    Inventors: Jorg Velker, Michael Scherz, Thomas Weller
  • 4-(Piperidyl-and pyrrolidyl-alkyl-ureido)-quinolines as urotensin II receptor antagonists
    Publication number: 20050043535
    Abstract: The invention relates to novel 1-pyridin-4-yl urea derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Application
    Filed: December 2, 2002
    Publication date: February 24, 2005
    Inventors: Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Jorg Velker, Thomas Weller
  • 1,2,3,4-tetrahydroisoquinolines derivatives
    Publication number: 20040242564
    Abstract: The invention relates to novel 1,2,3,4-tetrahydroisoquinoline derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Application
    Filed: July 13, 2004
    Publication date: December 2, 2004
    Inventors: Jorg Velker, Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Thomas Weller