Patents by Inventor Michael Schickler

Michael Schickler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9580504
    Abstract: Methods for treating specific populations of cancer patients, specifically patients suffering from cancer who undergo stem cell transplantation and were classified as positive by a pre-transplant metabolic imaging, by administering to the subject a therapeutically effective amount of a pidilizumab monoclonal antibody.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: February 28, 2017
    Assignee: CureTech Ltd.
    Inventors: Rinat Rotem-Yehudar, Michael Schickler
  • Patent number: 9416175
    Abstract: The present invention relates to humanized monoclonal antibodies, pharmaceutical compositions that include the same, and use thereof for the treatment of a variety of indications, particularly cancer and immunodeficiency disorders. In particular, the present invention provides modified antibodies or fragments thereof having specific amino acid modifications compared to the humanized monoclonal immunomodulatory antibody termed hBAT-1.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: August 16, 2016
    Assignee: CureTech Ltd.
    Inventors: Rinat Rotem-Yehudar, Michael Schickler
  • Publication number: 20140220010
    Abstract: The present invention relates to humanized monoclonal antibodies, pharmaceutical compositions that include the same, and use thereof for the treatment of a variety of indications, particularly cancer and immunodeficiency disorders. In particular, the present invention provides modified antibodies or fragments thereof having specific amino acid modifications compared to the humanized monoclonal immunomodulatory antibody termed hBAT-1.
    Type: Application
    Filed: March 18, 2014
    Publication date: August 7, 2014
    Applicant: CURETECH LTD.
    Inventors: Rinat ROTEM-YEHUDAR, Michael SCHICKLER
  • Patent number: 8686119
    Abstract: The present invention relates to humanized monoclonal antibodies, pharmaceutical compositions that include the same, and use thereof for the treatment of a variety of indications, particularly cancer and immunodeficiency disorders. In particular, the present invention provides modified antibodies or fragments thereof having specific amino acid modifications compared to the humanized monoclonal immunomodulatory antibody termed hBAT-1.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: April 1, 2014
    Assignee: CureTech Ltd.
    Inventors: Rinat Rotem-Yehudar, Michael Schickler
  • Publication number: 20130022595
    Abstract: The present invention relates to humanized monoclonal antibodies, pharmaceutical compositions that include the same, and use thereof for the treatment of a variety of indications, particularly cancer and immunodeficiency disorders. In particular, the present invention provides modified antibodies or fragments thereof having specific amino acid modifications compared to the humanized monoclonal immunomodulatory antibody termed hBAT-1.
    Type: Application
    Filed: July 23, 2012
    Publication date: January 24, 2013
    Applicant: CURETECH LTD.
    Inventors: Rinat Rotem-Yehudar, Michael Schickler
  • Publication number: 20090123413
    Abstract: The present invention relates to immunotherapy and more specifically concerns the use of immunostimulatory BAT monoclonal antibodies for treatment of a variety of immunodeficiency related diseases and disorders and malfunction or incompetence of the immune system.
    Type: Application
    Filed: August 23, 2005
    Publication date: May 14, 2009
    Inventors: Britta Hardy, Annat Raiter, Michael Schickler
  • Publication number: 20070060636
    Abstract: The present invention relates to a synthetic cannabinoid, dexanabinol, of enantiomeric purity in excess of 99.90%, or to a pharmaceutically acceptable salt, ester or solvate of said compound. The present invention also relates to pharmaceutical grade compositions comprising said compound of high enantiomeric purity, and uses thereof for prevention and treatment of neurological disorders, chronic degenerative diseases, CNS poisoning, cognitive impairment, inflammatory diseases or disorders, autoimmune diseases or disorders, pain, emesis, glaucoma and wasting syndromes.
    Type: Application
    Filed: August 14, 2006
    Publication date: March 15, 2007
    Inventors: Haim Aviv, Raphael Bar, Michael Schickler, Shimon Amselem
  • Publication number: 20040110827
    Abstract: The present invention relates to a synthetic cannabinoid, dexanabinol, of enantiomeric purity in excess of 99.90%, or to a pharmaceutically acceptable salt, ester or solvate of said compound. The present invention also relates to pharmaceutical grade compositions comprising said compound of high enantiomeric purity, and uses thereof for prevention and treatment of neurological disorders, chronic degenerative diseases, CNS poisoning, cognitive impairment, inflammatory diseases or disorders, autoimmune diseases or disorders, pain, emesis, glaucoma and wasting syndromes.
    Type: Application
    Filed: August 19, 2003
    Publication date: June 10, 2004
    Inventors: Haim Aviv, Raphael Bar, Michael Schickler, Shimon Amselem