Abstract: A brachytherapy seed applicator, comprising a hollow needle, an elongated tube configured for insertion into tissue, within the hollow needle, a hub at a proximal end of the elongated tube, one or more brachytherapy seeds carrying alpha-emitting radioactive particles, within the elongated tube, distanced from a distal tip of the elongated tube by at least one centimeter, and a stylet configured to be inserted into the elongated tube and to push the one or more brachytherapy seeds to a distal end of the elongated tube, when the elongated tube is in the tissue.

Abstract: Constructing AI flows involves navigating a large number of choices of components including vector databases, embedding models, text splitters, retrievers, and synthesizing LLMs. The complexity further escalates with the introduction of advanced agentic and non-agentic paradigms that involve additional components including verifiers, rewriters, and re-rankers, each with intricate hyperparameter options. These choices pose significant challenges in optimizing for tradeoffs between objectives such as latency, accuracy, and cost. To address these challenges, the systems and methods of the present disclosure conduct an efficient multi-objective search across an extensive space of agentic and non-agentic AI flows (e.g., RAG-based AI flows). Leveraging advances in Bayesian Optimization, the multi-objective search can, in some examples, identify high-performing (e.g., Pareto-optimal) flows that by definition cannot be improved upon in selected objectives (e.g.

Abstract: Surgical anchor constructs, fixation devices, and methods of manufacturing, as well as methods for tissue repairs are disclosed. A soft suture anchor has a sheath with varying densities along the length of the sheath. The anchor sheath can have different segments with different densities which can be provided in a pattern or a random manner. The segments with different densities allow secure fixation of the soft anchor within bone, and attachment of first tissue to second tissue.

Abstract: A method for manufacturing a distributor for refrigerant in components in a thermal management module is provided. The distributor has distributor openings for the refrigerant on an upper surface and/or a lower surface that faces away from the upper surface. Greater reliability, reduced installation space, and greater variability in the shape of the distributor are obtained in that the distributor is produced in a casting process, in which channel sections of channels passing through the distributor are obtained with a removable core in a mold. A method for manufacturing a thermal management module that contains such a distributor, as well as a distributor produced in this manner, and a thermal management module is provided.

Abstract: A thermal management module for a thermal management system is disclosed. The thermal management module includes a first heat exchanger for flowing through by a refrigerant and by a working medium fluidically separately with respect to the refrigerant. A second heat exchanger is provided including at least a first fluid path and at least a second fluid path, separate from the first fluid path, respectively for flowing through by the refrigerant. A connecting arrangement is arranged between the first heat exchanger and the second heat exchanger. The connecting arrangement connects the first heat exchanger and the second heat exchanger to one another mechanically and fluidically, so that the refrigerant can flow between the first heat exchanger and the second heat exchanger.

Abstract: A computer-implemented technique for creating and deploying an application receives a configuration file selecting a subset of preconfigured application bundles and associated configuration values. A template instance is generated to identify the selected bundles and define dependency relationships among the selected bundles. Based on the dependency relationships, an execution plan is determined to order provisioning and deployment actions. Execution resources in a deployment environment are provisioned according to the execution plan. For each selected bundle, a managed bundle object including executable logic and runtime configuration is created and deployed as a corresponding bundle endpoint. Communication between endpoints is configured by propagating an identifier of an upstream bundle endpoint into a runtime configuration of a dependent bundle endpoint. An application endpoint is exposed to receive a request and invoke at least one bundle endpoint to generate a response.

Abstract: A naphthalenesulfonic acid polycondensate is used as a plasticizer in a construction composition comprising sand and at least one cementitious binder. The naphthalenesulfonic acid polycondensate is obtainable by a condensation reaction of i) a naphthalenesulfonic acid, ii) an alkoxylated hydroxyaryl compound having a polyoxyalkylene chain with 3 to 130 oxyalkylene units, and iii) formaldehyde, in a weight ratio of i):ii) of 95:5 to 60:40, preferably 95:5 to 75:25, more preferably 95:5 to 85:15, wherein the sand has a methylene blue value according to DIN EN 933-9 of at least 10 g/kg. The naphthalenesulfonic acid polycondensate is largely clay-insensitive and its dispersibility is independent of the quality of the sand.

Abstract: A method and an apparatus for additive manufacturing of a component are described. At least one powder is provided. A plurality of component layers of the component to be manufactured are produced, wherein at least one powder fraction of the at least one powder is deposited to produce a component layer by electrostatically charging the powder fraction, electrostatically charging a deposition unit at least in some regions and picking up the electrostatically charged powder fractions by means of the deposition unit, which is electrostatically charged at least in some regions, and transferring it to a deposition surface. Various powder fractions to be deposited to produce the component layers are electrostatically charged with different polarity.

Abstract: The present disclosure relates to an alignment system. The alignment system includes a clamp portion including a curved member configured to contact a medial portion of a first metatarsal of a patient, and a retention element configured to releasably couple with a second metatarsal of the patient. The alignment system also includes an alignment portion releasably coupled with the clamp portion and including an alignment bar and an extension coupled with the alignment bar and configured to releasably couple with a guide arm. The retention element includes a shaft and a pair of protrusions extending from a distal-most point of the shaft, with the pair of protrusions extend substantially parallel to one another. Also disclosed is a method of coupling the alignment system to the anatomy of a patient, specifically to two bones in the foot of the patient.

Abstract: A method for manufacturing a distributor for refrigerant in components in a thermal management module is provided, distributor has distributor openings for the refrigerant on an upper surface and/or a lower surface that faces away from the upper surface. Greater reliability, reduced installation space, and greater variability in the shape of the distributor are obtained in that the distributor is produced in a casting process, in which channel sections of channels passing through the distributor are obtained with a removable core in a mold. A method for manufacturing a thermal management module that contains such a distributor, as well as a distributor produced in this manner, and a thermal management module is provided.

Abstract: A device for determining object data in relation to an object in the environment of at least one image camera is described. The device is configured to determine a camera-based feature tensor on the basis of at least one image from the image camera for a first point in time by means of a neural encoder network. Furthermore, the device is configured to transform and/or project the camera-based feature tensor from an image plane of the image onto a grid plane of an environment grid of the environment of the image camera in order to determine a transformed feature tensor. The device is furthermore configured to determine object data in relation to the object in the environment of the image camera on the basis of the transformed feature tensor by means of a neural evaluation network, the object data comprising one or more predicted properties of the object at a point in time succeeding the first point in time.

Abstract: The present disclosure relates to enabling active learning for object classification by an automotive vision system configured to perform visual perception tasks, based on which a vehicle is configured to perform at least one driving automation system feature. The automotive vision system determines one or more 3D bounding boxes and a corresponding object class within three-dimensional sets of automotive sensor data, which including at least one automotive camera frame, i.e. two-dimensional data, while a secondary vision system determines one or more 2D bounding box vectors for each automotive camera frame. Based at least on the one or more 2D bounding box vectors, a frame score is calculated for each automotive camera frame. Then, one or more automotive camera frames are provided to an oracle based on the corresponding frame scores. The oracle returns annotated camera frames, which may then be used to retrain the automotive vision system.

Abstract: A power machine includes a frame, a plurality of wheels, a steering actuator, a hub, a link and a bell crank. The plurality of wheels are in contact with a ground surface that serves as a horizontal reference. The steering actuator is mounted on the frame and is configured for substantially vertical extension and retraction. The hub includes a stationary portion and a rotatable portion, wherein one of the plurality of wheels is mounted on the rotatable portion to pivot about a first axis. The link has a first end pivotally connected to the rotatable portion of the hub. The bell crank comprises first, second and third pivot joints. The first pivot joint is attached to an end of the steering actuator, the second pivot joint is attached to the stationary portion of the hub, and the third pivot joint is attached to a second end of the link.

Abstract: A power machine can include operator input devices and a control system configured to command movement of actuators based on operator inputs received from the operator input devices. Movement of one or more of the actuators can be commanded based on input at one or more of the operator input devices and a response curve selected from a plurality of different response curves. Movement of one or more of the actuators can be based on a selected control mode for the power machine that corresponds to a selected control-function mapping of the operator input devices to the one or more actuators. A lift arm can be variously controlled to execute automatic or other operations. An excavator can be operated in a sustained-speed travel mode.

Abstract: A power machine can include operator input devices and a control system configured to command movement of actuators based on operator inputs received from the operator input devices. Movement of one or more of the actuators can be commanded based on input at one or more of the operator input devices and a response curve selected from a plurality of different response curves. Movement of one or more of the actuators can be based on a selected control mode for the power machine that corresponds to a selected control-function mapping of the operator input devices to the one or more actuators. A lift arm can be variously controlled to execute automatic or other operations. An excavator can be operated in a sustained-speed travel mode. Actuation of a bucket or other implement can be implemented based on signals from a material sensor.

Abstract: The present disclosure provides surprisingly useful fusion polypeptides including an immunomodulatory moiety and a metal-hydroxide binding moiety, as well as various related technologies, including methods of making and of using such fusion polypeptides.

Abstract: An adapter for a bike mount including a coupling plate, a first adapter section coupled to the coupling plate, and a second adapter section coupled to the coupling plate. The first adapter section is configured to receive a first bike axle. The second adapter section is configured to receive a second bike axle different than the first bike axle.

Abstract: A method and an apparatus for additive manufacturing of a component are described. At least one powder (P2) is provided. A plurality of component layers (B1, B2, B3) of the component to be manufactured are produced, wherein at least one powder fraction (A3) of the at least one powder (P2) is deposited to produce a component layer (B3) by electrostatically charging the powder fraction (A3), electrostatically charging a deposition unit (7) at least in some regions and picking up the electrostatically charged powder fractions (A3) by means of the deposition unit (7), which is electrostatically charged at least in some regions, and transferring it to a deposition surface (F). Various powder fractions (A3) to be deposited to produce the component layers (B1, B2, B3) are electrostatically charged with different polarity.

Abstract: An orthopedic instrument system includes a first cutting guide. The first cutting guide includes a base portion having an opening, an extension extending from the base portion having a cannulated opening in fluid communication with the opening of the base portion, and an actuator configured to occupy at least a portion of the opening of the base when in an actuated position within the cannulated opening. The system also includes a cutting insert configured to be received within the opening. The insert includes at least one depression, wherein the at least one depression comprises a volume which, when positioned within the opening, is common with at least a portion of the volume of the opening occupied by the actuator when in the actuated position.

Abstract: A radiotherapy source includes a base and radioactive atoms of one or more isotopes, which are attached to the base. The radioactive atoms have a radon release rate of at least 0.5 micro-Curie (?Ci) per centimeter length, and emit beta radiation achieving at 2 millimeters from the base an asymptotic dose of at least 10 Gy. Additionally, the ratio between the beta radiation asymptotic dose at a distance of 2 millimeters from the device to the radon release rate, is greater than 15 Gy/(microcurie/cm).