Patents by Inventor Michael Schmitt

Michael Schmitt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10387507
    Abstract: A system customizes a news document associated with a user of a news aggregation service. The system includes multiple news source servers that store news content and a remote news aggregation server. The news aggregation server creates a customized news document based on one or more personalized search queries received from a user. The news aggregation server fetches the news content from the multiple news source servers, aggregates the news content, and searches the aggregated news content based on the one or more personalized search queries. The news aggregation server provides selected news content to the customized news document based on results of the search.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: August 20, 2019
    Assignee: Google LLC
    Inventors: Krishna Bharat, Michael Schmitt, Michael Curtiss, Marissa Mayer, Kerah Cottrell, Brian Rakowski, Anurag Acharya
  • Patent number: 10370713
    Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.
    Type: Grant
    Filed: August 31, 2018
    Date of Patent: August 6, 2019
    Assignee: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
    Inventors: Jesse Salk, Lawrence A. Loeb, Michael Schmitt
  • Patent number: 10287631
    Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: May 14, 2019
    Assignee: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
    Inventors: Jesse Salk, Lawrence A. Loeb, Michael Schmitt
  • Publication number: 20190119748
    Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.
    Type: Application
    Filed: August 30, 2018
    Publication date: April 25, 2019
    Inventors: Michael Schmitt, Jesse Salk, Lawrence A. Loeb
  • Publication number: 20190119749
    Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.
    Type: Application
    Filed: August 30, 2018
    Publication date: April 25, 2019
    Inventors: Michael Schmitt, Jesse Salk, Lawrence A. Loeb
  • Publication number: 20190093160
    Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.
    Type: Application
    Filed: August 30, 2018
    Publication date: March 28, 2019
    Inventors: Michael Schmitt, Jesse Salk, Lawrence A. Loeb
  • Publication number: 20190093161
    Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.
    Type: Application
    Filed: August 30, 2018
    Publication date: March 28, 2019
    Inventors: Michael Schmitt, Jesse Salk, Lawrence A. Loeb
  • Publication number: 20190093162
    Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.
    Type: Application
    Filed: August 31, 2018
    Publication date: March 28, 2019
    Inventors: Michael Schmitt, Jesse Salk, Lawrence A. Loeb
  • Patent number: 10162802
    Abstract: A system provides client access to customized news content. The system includes a custom news source server and a news search server. The custom news source server periodically sends one or more customized search queries to a news search server. The news search server fetches news content from multiple news source servers and aggregates the news content. The news search server also periodically receives the one or more search queries from the custom news source server, searches the aggregated news content based on the one or more search queries, and periodically provides selected news content to the custom news server based on results of the searches. The custom news source server permits access to clients, from across a network, to the selected news content provided by the news search server.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: December 25, 2018
    Assignee: GOOGLE LLC
    Inventors: Krishna Bharat, Michael Schmitt, Mike Curtiss, Marissa Mayer, Anurag Acharya, Srdjan Mitrovic, Vijay Boyapati
  • Publication number: 20180363053
    Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.
    Type: Application
    Filed: August 31, 2018
    Publication date: December 20, 2018
    Inventors: Michael Schmitt, Jesse Salk, Lawrence A. Loeb
  • Publication number: 20180363051
    Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.
    Type: Application
    Filed: August 31, 2018
    Publication date: December 20, 2018
    Inventors: Michael Schmitt, Jesse Salk, Lawrence A. Loeb
  • Publication number: 20180363052
    Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.
    Type: Application
    Filed: August 31, 2018
    Publication date: December 20, 2018
    Inventors: Michael Schmitt, Jesse Salk, Lawrence A. Loeb
  • Patent number: 10119923
    Abstract: Methodologies, systems, apparatus, and non-transitory computer-readable media are described herein to facilitate acquisition of volumetric data and volumetric image reconstruction. An imaging system can be configured to transport an object at a speed relative to the scan path of an X-ray source such that insufficient measurement data is collected for classically complete geometrical coverage. Iterative image reconstruction techniques may be used to generate volumetric images based on measured volumetric data of at least a portion of the object.
    Type: Grant
    Filed: October 19, 2015
    Date of Patent: November 6, 2018
    Assignee: L3 Security & Detection Systems, Inc.
    Inventors: Michael Schmitt, Andrew D. Foland, Boris Oreper
  • Publication number: 20180289140
    Abstract: A brush head (32) including a neck (40) having a brush neck (42); a plurality of bristle tufts (21), each of which includes a plurality of bristle strands with a free end (25) and a proximal end (23), the proximal end having a proximal end head portion (26); a plurality of retention rings (50), each configured to receive the proximal end of at least one of the plurality of bristle tufts; an elastomeric matrix (30) bonded to at least a portion of the brush neck, the plurality of retention rings, and the proximal end of the plurality of bristle tufts, wherein the proximal end head portion of each of the plurality of bristle tufts is configured to comprise a space (27) between the proximal end head portion and the respective retention ring.
    Type: Application
    Filed: May 9, 2016
    Publication date: October 11, 2018
    Inventors: EVAN DAK WAH DENGLER, MICHAEL SCHMITT
  • Patent number: 10095752
    Abstract: Methods and apparatus are described for scoring documents in response, in part, to parameters related to the document, source, and/or cluster score. Methods and apparatus are also described for scoring a cluster in response, in part, to parameters related to documents within the cluster and/or sources corresponding to the documents within the cluster. In one embodiment, the invention may identify the source; detect a plurality of documents published by the source; analyze the plurality of documents with respect to at least one parameter, and determine a source score for the source in response, in part, to the parameter. In another embodiment, the invention may identify a topic; identify a plurality of clusters in response to the topic; analyze at least one parameter corresponding to each of the plurality of clusters; and calculate a cluster score for each of the plurality of clusters in response, in part, to the parameter.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: October 9, 2018
    Assignee: Google LLC
    Inventors: Michael Schmitt, Krishna Bharat, Michael Curtiss
  • Patent number: 10011225
    Abstract: A system and a method for detecting a replacement component of a device. The method includes detecting a first identifier of a device which includes at least one replaceable component, using a mobile terminal; detecting a second identifier of at least one replacement component, using the mobile terminal; transmitting the detected first and second identifiers to a computing device; generating a control signal based on the first and second identifiers; transmitting the generated control signal to the device; and controlling the device with the aid of the control signal.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: July 3, 2018
    Assignee: ROBERT BOSCH GMBH
    Inventors: Michael Schmitt, Peter Schmitt
  • Patent number: 10005502
    Abstract: A device for exerting torque on an object includes: at least one rotating mass rotatably supported about an axis of rotation; a drive for driving the rotating mass; a bearing which enables a change in the alignment of the axis of rotation relative to the object; and a coupling unit which engages on the bearing and couples the rotating mass to the object.
    Type: Grant
    Filed: March 26, 2013
    Date of Patent: June 26, 2018
    Assignee: ROBERT BOSCH GMBH
    Inventors: Wolfgang Carle, Michael Schmitt
  • Publication number: 20180142293
    Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.
    Type: Application
    Filed: July 26, 2017
    Publication date: May 24, 2018
    Inventors: Michael Schmitt, Jesse Salk, Lawrence A. Loeb
  • Patent number: 9752188
    Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: September 5, 2017
    Assignee: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
    Inventors: Michael Schmitt, Jesse Salk, Lawrence A. Loeb
  • Patent number: 9747230
    Abstract: A memory system includes a two memory modules and a memory controller. The memory modules each include at least a first memory package corresponding to a first number of memory ranks (e.g. one memory rank) and a second memory package corresponding to a second number of memory ranks (e.g. two memory ranks) that is greater than the first number of memory ranks. For each module, the memory packages may be asymmetrically staggered such that one memory package is further from the memory controller than the other memory package. The memory controller is coupled to the memory packages of both modules via a common data line and generates control information for controlling the on-die termination (ODT) of the memory packages.
    Type: Grant
    Filed: October 14, 2013
    Date of Patent: August 29, 2017
    Assignee: Rambus Inc.
    Inventors: Minghui Han, Amir Amirkhany, Ravindranath Kollipara, Ralf Michael Schmitt