Patents by Inventor Michael Schwake

Michael Schwake has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lysosome membrane protein 2 (LIMP-2) based peptides and related uses
    Patent number: 10286038
    Abstract: A group of LIMP-2 peptides, LIMP-2 polypeptides, variants thereof, and pharmaceutical compositions comprising the LIMP-2 peptides, LIMP-2 polypeptides, or variants thereof are described. The disclosed peptides and polypeptides preferably comprise an amino acid sequence that is sufficient for providing a biological activity associated with LIMP-2, which may include binding and/or activating biological molecules such as ?-glucocerebrosidase and binding viral protein 1 (VP1) of enterovirus 71 (E71) or coxsackievirus A16 (CA16). Also disclosed are methods of using the LIMP-2 peptides, LIMP-2 polypeptides, and variants thereof as therapeutics for treating diseases and disorders associated with ?-glucocerebrosidase activity in subjects in need thereof.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: May 14, 2019
    Assignee: Northwestern University
    Inventors: Michael Schwake, Dimitri Krainc
  • LIMP-2 BASED PEPTIDES AND RELATED USES
    Publication number: 20170258870
    Abstract: Disclosed are LIMP-2 peptides, LIMP-2 polypeptides, variants thereof, and pharmaceutical compositions comprising the LIMP-2 peptides, LIMP-2 polypeptides, or variants thereof. The disclosed peptides and polypeptides preferably comprise an amino acid sequence that is sufficient for providing a biological activity associated with LIMP-2, which may include binding and/or activating biological molecules such as ?-glucocerebrosidase and binding viral protein 1 (VP1) of enterovirus 71 (E71) or coxsackievirus A16 (CA16). Also disclosed are methods of using the LIMP-2 peptides, LIMP-2 polypeptides, and variants thereof as therapeutics for treating diseases and disorders associated with ?-glucocerebrosidase activity in subjects in need thereof.
    Type: Application
    Filed: March 10, 2017
    Publication date: September 14, 2017
    Applicant: Northwestern University
    Inventors: Michael Schwake, Dimitri Krainc