Patents by Inventor Michael Sean Esplin

Michael Sean Esplin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Identification and quantification of biomarkers for evaluating the risk of preterm birth
    Patent number: 10247736
    Abstract: Described herein are methods for evaluating the risk of preterm birth in pregnant subjects. The methods involve detecting and quantifying one or more biomarkers associated with preterm birth in a biological sample from the subject. Also described herein are isolated biomarkers and kits useful in predicting the risk of preterm birth.
    Type: Grant
    Filed: July 17, 2008
    Date of Patent: April 2, 2019
    Assignees: BRIGHAM YOUNG UNIVERSITY, UNIVERSITY OF UTAH RESEARCH FOUNDATION, IHC HEALTH SERVICES
    Inventors: Steven William Graves, Michael Sean Esplin, Craig Dan Thulin
  • SERUM LIPID BIOMARKERS OF PREECLAMPSIA
    Publication number: 20180313856
    Abstract: A panel of lipid biomarkers of preeclampsia in pregnant women, useful prior to onset of symptoms to identify women at risk of preeclampsia as early as 12-14 weeks gestation is disclosed. Methods of diagnosing a pregnant subject at risk of developing preeclampsia, and methods of reducing symptoms or preventing the onset of preeclampsia in a pregnant subject, employing the disclosed lipid biomarkers are also disclosed.
    Type: Application
    Filed: October 26, 2016
    Publication date: November 1, 2018
    Applicant: Brigham Young University
    Inventors: Steven William GRAVES, Michael Sean ESPLIN
  • Serum proteomics system and associated methods
    Patent number: 8552364
    Abstract: Methods for proteomic analysis are provided. For example, in one aspect a method for identifying and sequencing a peptide may include fractionating a biological sample containing a peptide of interest to at least partially isolate the peptide, obtaining mass spectra of the peptide, and accelerating the peptide into a collision chamber at a plurality of discrete collision energies for a discrete period of time to form a plurality of peptide fragments for each of the plurality of discrete collision energies.
    Type: Grant
    Filed: December 26, 2007
    Date of Patent: October 8, 2013
    Assignees: Brigham Young University, University of Utah Research Foundation, IHC Health Services
    Inventors: Steven W. Graves, Craig Dan Thulin, Michael Sean Esplin
  • IDENTIFYING AND QUANTIFYING BIOMARKERS ASSOCIATED WITH PREECLAMPSIA
    Publication number: 20110247404
    Abstract: Described herein are methods for testing pregnant subjects for preeclampsia by detecting and quantifying at least one biomarker associated with preeclampsia in a biological sample from the subject.
    Type: Application
    Filed: June 24, 2009
    Publication date: October 13, 2011
    Applicants: UNIVERSITY OF UTAH RESEARCH FOUNDATION, IHC HEALTH SERVICES, INC., BRIGHAM YOUNG UNIVERSITY
    Inventors: Steven W Graves, Michael Sean Esplin
  • IDENTIFICATION AND QUANTIFICATION OF BIOMARKERS FOR EVALUATING THE RISK OF PRETERM BIRTH
    Publication number: 20100297679
    Abstract: Described herein are methods for evaluating the risk of preterm birth in pregnant subjects. The methods involve detecting and quantifying one or more biomarkers associated with preterm birth in a biological sample from the subject. Also described herein are isolated biomarkers and kits useful in predicting the risk of preterm birth.
    Type: Application
    Filed: July 17, 2008
    Publication date: November 25, 2010
    Inventors: Steven William Graves, Michael Sean Esplin, Craig Dan Thulin
  • SERUM PROTEOMICS SYSTEM AND ASSOCIATED METHODS
    Publication number: 20100163721
    Abstract: Methods for proteomic analysis are provided. For example, in one aspect a method for identifying and sequencing a peptide may include fractionating a biological sample containing a peptide of interest to at least partially isolate the peptide, obtaining mass spectra of the peptide, and accelerating the peptide into a collision chamber at a plurality of discrete collision energies for a discrete period of time to form a plurality of peptide fragments for each of the plurality of discrete collision energies.
    Type: Application
    Filed: December 26, 2007
    Publication date: July 1, 2010
    Applicant: BRIGHAM YOUNG UNIVERSITY
    Inventors: Steven William Graves, Craig Dan Thulin, Michael Sean Esplin