Abstract: A portable monitoring device and a method for monitoring and alerting physiological parameters of a patient are provided. The portable monitoring device comprises a housing, parameter sensing devices, a processing unit, and data communication units. The housing defines an inner surface for establishing physical contact with the patient's body part, and an outer surface opposing the inner surface. The parameter sensing devices acquire physiological data associated with the patient's physiological parameters. The processing unit processes the acquired physiological data and patient information. The data communication units, capable of synchronizing with responder devices, transmit the processed physiological data and the patient information to a base monitoring unit, a remote monitoring station, and/or responder devices via one or more transceivers and data communication interfaces for initiating relief measures.