Patents by Inventor Michael Sean Phillips

Michael Sean Phillips has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6281346
    Abstract: The rat ob receptor gene has been isolated and cloned. Two different alleles have been identified: the wild-type, and the fa-allele which differs from the wild type by only one base pair. The base pair change, however introduces an MspI restriction site into the DNA sequence, and also results in an amino acid change. Also part of the invention are the receptors, vectors containing the nucleic acid encoding the receptors, host cells transformed with this gene, and assays which use the gene or protein and identify new ligands.
    Type: Grant
    Filed: February 20, 1997
    Date of Patent: August 28, 2001
    Assignee: Merck & Co., Inc.
    Inventors: John W. Hess, C. Thomas Caskey, Qingyun Liu, Michael Sean Phillips
  • Patent number: 6258944
    Abstract: The ob receptor has numerous isoforms resulting from alternative splicaing; three novel isoforms, designated c′, f, and g are disclosed. The nucleic acids encoding these isoforms are taught. Also part of the invention are vectors containing the nucleic acid encoding the receptors, host cells transformed with these genes, and assays which use the genes or protein isoforms.
    Type: Grant
    Filed: May 6, 1997
    Date of Patent: July 10, 2001
    Assignee: Merck & Co., Inc.
    Inventors: C. Thomas Caskey, Patricia Hey, John W. Hess, Michael Sean Phillips