Abstract: Provided is a string suppressor for a crossbow comprising a first suppressor axis; a first suppressor plane containing the first suppressor axis; an elastomeric pad elongated along the first suppressor axis to define a first pad end, and a second pad end opposite the first pad end along the first suppressor axis; wherein the first pad end has a feature adapted for engagement with a crossbow riser; and wherein the second pad end has a string groove formed therein, the string groove being coextensive with the first suppressor plane, and has a cam groove formed therein, the cam groove being coextensive with the first suppressor plane, the cam groove being wide enough to provide a clearance fit with an associated cam.

Abstract: A crossbow cocking system may include a sled having first and second arms, an elongated cocking cable, a first handle, a second handle, a first engagement feature and a second engagement feature. The first and second engagement features may be used to engage the first handle to the first arm and the second handle to the second arm, respectively. Each engagement feature may include at least one cavity and at least one protrusion that is received in the cavity for engagement. The handles may be disengaged to permit a user to cock the crossbow.

Abstract: A nock insert may have an axis of elongation defining an axial direction and radial directions, a bowstring reception surface adapted to receive a bowstring, and an insert portion adapted for insertion into an arrow body. The nock insert may have one or more centering features having one or more spring tabs. Each spring tab may have a first end attached to the insert portion and a second free end extending axially from the first end and having a contact surface. The contact surfaces of each spring tab may be inherently biased outwardly in a radial direction and adapted to be radially deflected upon insertion of the insert portion into the arrow body.

Abstract: Provided is a mid-limb cam crossbow system comprising a beam; a bow assembly having a first bow limb of length L1 and second bow limb of length L2; a first cam engaged with the first bow limb at a point between (0.15)L1 and (0.75)L1 from the limb end; a second cam engaged with the second bow limb at a point between (0.15)L2 and (0.75)L2 from the limb end; a first power string engaged with the first cam and a region on the second bow limb greater than (0.75)L2 from the limb end; a second power string engaged with the second cam and a region on the first bow limb greater than (0.75)L1 from the limb end; and a bowstring engaged between the first cam and the second cam. The bow assembly may be configured in an uncocked configuration or a cocked configuration. L1 and L2 are between 15 centimeters and 65 centimeters.

Abstract: Provided is a crossbow cocking system comprising a sled, an elongated cocking cable, a first handle, and a second handle. The sled may have a first side having a first bowstring retainer, a first arm having a first set of handle engagement features adapted for engagement with a first handle, and a first pulley rotatably engaged with the first arm; and a second side having a second bowstring retainer, and a second arm having a second set of handle engagement features adapted for engagement with a second handle, a second pulley rotatably engaged with the second arm. The first and the second handle may each be engaged to the elongated cocking cable, and be ergonomically adapted to permit an associated user to operate the each handle during a cocking operation with a hand in a vertical hand position.

Abstract: Provided is a crossbow cocking device comprising a speed-sensitive clutch having a housing; an input shaft in operational engagement with an associated crossbow cocking cable, and in selectable rotational engagement with said housing; and wherein, below a critical rotational speed of the input shaft with respect to the housing, the speed-sensitive clutch will maintain a disengaged state, and at or above the critical speed of the input shaft with respect to the housing, said speed sensitive clutch will automatically switch to an engaged state.

Abstract: A crossbow assembly may include a riser and a pair of bow limbs that attach to the riser. The limb attachment surfaces on the riser may be separated such that a minimum distance between them is not greater than 5 inches. The minimum distance may be at least as wide as a user's foot. The riser may have a U-shaped opening that extends between the limb attachment surfaces. The limb attachment surfaces may be angled between 60 and 30 degrees. The riser may have a foot stirrup that begins behind the limb attachment surfaces and extends beyond them.

Abstract: Provided is a crossbow cocking system comprising a crossbow stock having a first side and a second side opposite the first side; a first receptacle extending through the stock from the first side of the stock to the second side of the stock; a first adapter plate adapted for selectable and operational engagement with the first receptacle; and a cocking device engaged with the first adapter plate, and extending through the first adapter plate.

Abstract: Provided is a crossbow comprising an elongated barrel having a front barrel end and a rear barrel end opposite the front barrel end, and a first barrel side and a second barrel side opposite the first barrel side; a bow engaged with the elongated barrel; an elongated bowstring having a first end and a second end opposite the first end; a first bowstring guide engaged with the first barrel side, the first bowstring guide being adapted to push the bowstring toward the second barrel side while the bowstring is moved between a cocked position and an uncocked position; and a second bowstring guide engaged with the second barrel side, the second bowstring guide being adapted to push the bowstring toward the first barrel side while the bowstring is moved between a cocked position and an uncocked position.

Abstract: Provided is a universal nock system comprising a first axis defining an axial direction and radial directions perpendicular to the axial direction; a nock having, a first side having a bowstring reception surface having concave channels, a second side opposite the first side, an axial contact surface, and an exterior surface; an insert portion extending from the second side of the nock, elongated along the first axis, and adapted for insertion into an associated arrow body, the insert portion having, a first end, a second end opposite the first end having a centering feature of the second end, the centering feature of the second end having contact surfaces, and a middle portion located along the first axis of elongation between the first end and the second end, the middle portion having a centering feature of the middle portion, the centering feature of the middle portion having contact surfaces.

Abstract: Provided is a crossbow comprising a bow having a riser having a first side and a second side opposite the first side, a first limb set engaged to the first side, a second limb set engaged to the second side, a first cam set engaged to the first limb set, a second cam set engaged to the second limb set; an adjustable pulley set having at least a first pulley and a second pulley, wherein the pulley set is operationally engaged with and selectably movable with respect to the first cam, or the second cam, or the riser; a first power cord set extending from the first cam set and at least partially around the first pulley; and a second power cord set extending from the second cam set and at least partially around the second pulley.

Abstract: Provided is a crossbow cocking system comprising a sled, an elongated cocking cable, a first handle, and a second handle. The sled may have a first side having a first bowstring retainer, a first arm having a first set of handle engagement features adapted for engagement with a first handle, and a first pulley rotatably engaged with the first arm; and a second side having a second bowstring retainer, and a second arm having a second set of handle engagement features adapted for engagement with a second handle, a second pulley rotatably engaged with the second arm. The first and the second handle may each be engaged to the elongated cocking cable, and be ergonomically adapted to permit an associated user to operate the each handle during a cocking operation with a hand in a vertical hand position.

Abstract: Provided is a crossbow cocking device comprising a speed-sensitive clutch having a housing; an input shaft in operational engagement with an associated crossbow cocking cable, and in selectable rotational engagement with said housing; and wherein, below a critical rotational speed of the input shaft with respect to the housing, the speed-sensitive clutch will maintain a disengaged state, and at or above the critical speed of the input shaft with respect to the housing, said speed sensitive clutch will automatically switch to an engaged state.

Abstract: A crossbow assembly may include a riser and a pair of bow limbs that attach to the riser. The limb attachment surfaces on the riser may be separated such that a minimum distance between them is not greater than 5 inches. The minimum distance may be at least as wide as a user's foot. The riser may have a U-shaped opening that extends between the limb attachment surfaces. The limb attachment surfaces may be angled between 60 and 30 degrees. The riser may have a foot stirrup that begins behind the limb attachment surfaces and extends beyond them.

Abstract: Provided is a crossbow cocking system comprising a crossbow stock having a first side and a second side opposite the first side; a first receptacle extending through the stock from the first side of the stock to the second side of the stock; a first adapter plate adapted for selectable and operational engagement with the first receptacle; and a cocking device engaged with the first adapter plate, and extending through the first adapter plate.

Abstract: Provided is a mid-limb cam crossbow system comprising a beam; a bow assembly having a first bow limb of length L1 and second bow limb of length L2; a first cam engaged with the first bow limb at a point between (0.15)L1 and (0.75)L1 from the limb end; a second cam engaged with the second bow limb at a point between (0.15)L2 and (0.75)L2 from the limb end; a first power string engaged with the first cam and a region on the second bow limb greater than (0.75)L2 from the limb end; a second power string engaged with the second cam and a region on the first bow limb greater than (0.75)L1 from the limb end; and a bowstring engaged between the first cam and the second cam. The bow assembly may be configured in an uncocked configuration or a cocked configuration. L1 and L2 are between 15 centimeters and 65 centimeters.

Abstract: A crossbow assembly may include a riser and a pair of bow limbs that attach to the riser. The limb attachment surfaces on the riser may be separated such that a minimum distance between them is not greater than 5 inches. The minimum distance may be at least as wide as a user's foot. The riser may have a U-shaped opening that extends between the limb attachment surfaces. The limb attachment surfaces may be angled between 60 and 30 degrees. The riser may have a foot stirrup that begins behind the limb attachment surfaces and extends beyond them.

Abstract: Provided is a crossbow cocking system comprising a crossbow stock having a first side and a second side opposite the first side; a first receptacle extending through the stock from the first side of the stock to the second side of the stock; a first adapter plate adapted for selectable and operational engagement with the first receptacle; and a cocking device engaged with the first adapter plate, and extending through the first adapter plate.

Abstract: Provided is a universal nock system comprising a first axis defining an axial direction and radial directions perpendicular to the axial direction; a nock having, a first side having a bowstring reception surface having concave channels, a second side opposite the first side, an axial contact surface, and an exterior surface; an insert portion extending from the second side of the nock, elongated along the first axis, and adapted for insertion into an associated arrow body, the insert portion having, a first end, a second end opposite the first end having a centering feature of the second end, the centering feature of the second end having contact surfaces, and a middle portion located along the first axis of elongation between the first end and the second end, the middle portion having a centering feature of the middle portion, the centering feature of the middle portion having contact surfaces.

Abstract: Combinations of Bruton's tyrosine kinase (Btk) inhibitors, e.g., 1-((R)-3-(4-amino-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, with a second anticancer agent are provided. Also provided are methods of treating cancers, and autoimmune disorders by administering combinations of Bruton's tyrosine kinase (Btk) inhibitors, e.g., 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, and second anticancer agents.