Abstract: A metallic seal includes a first leg having a first sealing profile and a second leg having a second sealing profile. The metallic seal also includes an inner bore including a first inner diameter and a second inner diameter. The metallic seal further includes a first radial contact point, along the first sealing profile and a second radial contact point, along the second sealing profile, wherein the second radial contact point is a larger outer diameter of the seal than the first radial contact point.

Abstract: A metallic seal includes a first leg having a first sealing profile and a second leg having a second sealing profile. The metallic seal also includes an inner bore including a first inner diameter and a second inner diameter. The metallic seal further includes a first radial contact point, along the first sealing profile and a second radial contact point, along the second sealing profile, wherein the second radial contact point is a larger outer diameter of the seal than the first radial contact point.

Abstract: A tubing hanger comprising an annulus communication cavity and an annulus isolation device (AID) disposed within the cavity. The AID is operable to move between a closed position in which fluid communication to a downhole annulus via the cavity is prevented and an open position in fluid communication to the downhole annulus via the cavity is permitted. A metal sleeve surrounds the AID and is disposed between the AID and a surface defining the cavity. The AID further comprises one or more metal seal elements that form a dynamic metal-to-metal (MtM) seal with the metal sleeve. The present disclosure also relates to the metal seal element.

Abstract: A system for cross-channel communication for effectors in an electric aircraft is presented. The system may include a flight component of an electric aircraft. The system may include a plurality of effectors, wherein the plurality of effectors may be configured to control the flight component. The system may include a plurality of flight controllers communicatively connected to the plurality of effectors, wherein the plurality of flight controllers may be configured to receive an input, generate a command as a function of the input and transmit the command to the plurality of effectors. The system may include a plurality of networks communicatively connected to the plurality of effectors and the plurality of flight controllers, wherein the plurality of networks may be configured to receive the command from the plurality of flight controllers and transmit the command to the plurality of effectors.

Abstract: Technology is configured to facilitate client device engagement with three-dimensional architectural models. A particular focus of the technology is enabling users of mobile and/or VR devices to perform virtual property inspections, including in a collaborative engagement scenario. While some embodiments will be described herein with particular reference to those applications, it will be appreciated that the present disclosure is not limited to such a field of use, and is applicable in broader contexts.

Abstract: A system for cross-channel communication for effectors in an electric aircraft is presented. The system may include a flight component of an electric aircraft. The system may include a plurality of effectors, wherein the plurality of effectors may be configured to control the flight component. The system may include a plurality of flight controllers communicatively connected to the plurality of effectors, wherein the plurality of flight controllers may be configured to receive an input, generate a command as a function of the input and transmit the command to the plurality of effectors. The system may include a plurality of networks communicatively connected to the plurality of effectors and the plurality of flight controllers, wherein the plurality of networks may be configured to receive the command from the plurality of flight controllers and transmit the command to the plurality of effectors.

Abstract: A water treatment system for producing potable water and water for irrigation from saline water, the system includes an electrodialysis apparatus including one or more monovalent selective membranes and having an inlet fluidly connectable to a source of water to be treated, a diluate outlet, and a concentrate outlet, a nanofiltration apparatus positioned downstream of the electrodialysis apparatus and having an inlet fluidly connectable to the diluate outlet of the electrodialysis apparatus, a permeate outlet, and a retentate outlet, and an electrolyzer in fluid communication with one of the concentrate outlet and the retentate outlet, and configured to generate a product stream including one or more of chlorine gas, hypochlorite ion, sodium hydroxide, sulfuric acid, hydrochloric acid, or sodium hypochlorite.

Abstract: Methods of producing an ion exchange membrane support are disclosed. The methods include saturating a polymeric microporous substrate with a charged monomer solution comprising at least one functional monomer, a cross-linking agent, and an effective amount of at least one photopolymerization initiator and polymerizing the at least one functional monomer by exposing the saturated polymeric microporous substrate to ultraviolet light under conditions effective to cross-link the at least one functional monomer and produce the ion exchange membrane support. Methods of producing a monovalent selective ion exchange membrane are also disclosed. The methods include functionalizing an exterior surface of the ion exchange membrane support with a charged compound layer, drying the ion exchange membrane support and soaking the ion exchange membrane support in a solution comprising an acid or a base for an amount of time effective to produce the monovalent selective ion exchange membrane.

Abstract: A system for cross-channel communication for effectors in an electric aircraft is presented. The system may include a flight component of an electric aircraft. The system may include a plurality of effectors, wherein the plurality of effectors may be configured to control the flight component. The system may include a plurality of flight controllers communicatively connected to the plurality of effectors, wherein the plurality of flight controllers may be configured to receive an input, generate a command as a function of the input and transmit the command to the plurality of effectors. The system may include a plurality of networks communicatively connected to the plurality of effectors and the plurality of flight controllers, wherein the plurality of networks may be configured to receive the command from the plurality of flight controllers and transmit the command to the plurality of effectors.

Abstract: An electrochemical separation device includes a first electrode, a second electrode, and a cell stack including a plurality of sub-blocks each having alternating depleting compartments and concentrating compartments and each including frame and channel portions disposed between the first electrode and the second electrode. An internal seal formed of a first material is disposed between and in contact with the channel portions between adjacent sub-blocks in the cell stack and configured to prevent leakage between depleting compartments and concentrating compartments in the adjacent sub-blocks. An external seal formed of a second material having at least one material parameter different from the first material is disposed between and in contact with the frames of the adjacent sub-blocks in the cell stack and configured to prevent leakage from an internal volume of the electrochemical separation device to outside of the electrochemical separation device.

Abstract: An electrochemical separation device includes a first electrode, a second electrode, and a cell stack including a plurality of sub-blocks each having alternating depleting compartments and concentrating compartments and each including frame and channel portions disposed between the first electrode and the second electrode. An internal seal formed of a first material is disposed between and in contact with the channel portions between adjacent sub-blocks in the cell stack and configured to prevent leakage between depleting compartments and concentrating compartments in the adjacent sub-blocks. An external seal formed of a second material having at least one material parameter different from the first material is disposed between and in contact with the frames of the adjacent sub-blocks in the cell stack and configured to prevent leakage from an internal volume of the electrochemical separation device to outside of the electrochemical separation device.

Abstract: A system for cross-channel communication for effectors in an electric aircraft is presented. The system may include a flight component of an electric aircraft. The system may include a plurality of effectors, wherein the plurality of effectors may be configured to control the flight component. The system may include a plurality of flight controllers communicatively connected to the plurality of effectors, wherein the plurality of flight controllers may be configured to receive an input, generate a command as a function of the input and transmit the command to the plurality of effectors. The system may include a plurality of networks communicatively connected to the plurality of effectors and the plurality of flight controllers, wherein the plurality of networks may be configured to receive the command from the plurality of flight controllers and transmit the command to the plurality of effectors.

Abstract: A method of operating an electrochemical cell including introducing an aqueous solution into the electrochemical cell, applying a current across an anode and a cathode to produce a product, monitoring the voltage, dissolved hydrogen, or a condition of the aqueous solution, and applying the current in a pulsed waveform responsive to one of the measured parameters is disclosed. An electrochemical system including an electrochemical cell including an anode and a cathode, a source of an aqueous solution having an outlet fluidly connectable to the electrochemical cell, a sensor for measuring a parameter, and a controller configured to cause the anode and the cathode to apply the current in a pulsed waveform responsive to the parameter measurement is disclosed. Methods of suppressing accumulation of hydrogen gas within the electrochemical cell are also disclosed. Methods of facilitating operation of an electrochemical cell are also disclosed.

Abstract: The present invention provides, among other things, compositions and methods for prophylaxis and treatment of autoimmune disease. The present invention is based, in part, on the surprising discovery that a human interleukin-2 mutein activates proliferation of regulatory T cells. In one aspect, the present invention provides compositions and methods for proliferation of regulatory T cells. In another aspect, a human interleukin-2 (IL-2) mutein comprising an amino acid sequence that is at least 90% identical to the wild type IL-2 protein is described, wherein the IL-2 mutein has at least one amino acid substitution selected from a group consisting of T111H, T37Y, E15T, M23L, P34F, E68F and E62A.

Abstract: An electrochemical separation device includes a first electrode, a second electrode, and a cell stack including a plurality of sub-blocks each having alternating depleting compartments and concentrating compartments and each including frame and channel portions disposed between the first electrode and the second electrode. An internal seal formed of a first material is disposed between and in contact with the channel portions between adjacent sub-blocks in the cell stack and configured to prevent leakage between depleting compartments and concentrating compartments in the adjacent sub-blocks. An external seal formed of a second material having at least one material parameter different from the first material is disposed between and in contact with the frames of the adjacent sub-blocks in the cell stack and configured to prevent leakage from an internal volume of the electrochemical separation device to outside of the electrochemical separation device.

Abstract: Technology is configured to facilitate client device engagement with three-dimensional architectural models. A particular focus of the technology is enabling users of mobile and/or VR devices to perform virtual property inspections, including in a collaborative engagement scenario. While some embodiments will be described herein with particular reference to those applications, it will be appreciated that the present disclosure is not limited to such a field of use, and is applicable in broader contexts.

Abstract: A parts library apparatus of predesigned freestanding three dimensional box like forms representing modest room sized units, each complete with a floor, walls and a roof of a particular shape and pitch and further categorised as either room units with full height walls and lower pitched roofs, or loft units with higher pitched roofs and some short wall or no wall sides, together with three types of unit assembly defined as non-core, core, or a combination of both, so that by selecting a kit of parts containing at least one type of unit from the parts library, a user can assemble them in accordance with at least one of the three types of unit assembly to form at least one model building and building design which can be easily reconfigured to produce many alternative design options.

Abstract: An electrochlorination system includes an electrolyzer fluidically connectable between a source of feed fluid and a product fluid outlet, and a sub-system configured to one of increase a pH of the feed fluid, or increase a ratio of monovalent to divalent ions in the feed fluid, upstream of the electrolyzer.

Abstract: A data storage system can organize a semiconductor memory into a first data set and a second data set with a first queue populated with a first data access request from a host. An assignment of an arbitration weight to the first queue with an arbitration circuit corresponds with the first queue being skipped during a deterministic window based on the arbitration weight.