Patents by Inventor Michael Shelanski

Michael Shelanski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PLURIPOTENT STEM CELLS DERIVED FROM NON-CRYOPROTECTED FROZEN TISSUE AND METHODS FOR MAKING AND USING THE SAME
    Publication number: 20160130561
    Abstract: In some embodiments the present invention provides cells, such as pluripotent stem cells and differentiated cells, derived from tissue samples that have been frozen without a cryoprotective agent, and also cell panels comprising such cells, model systems comprising such cells, and methods for making and using such cells, cell panels, and model systems.
    Type: Application
    Filed: June 13, 2014
    Publication date: May 12, 2016
    Inventors: Andrew Sproul, John Crary, Lauren Ab Vensand, Carmen Dusenberry, Scott Noggle, Michael Shelanski
  • ATF4 As A Therapeutic Target In Alzheimers Disease And Other Neurological Disorders
    Publication number: 20090148450
    Abstract: The present invention relates to methods and compositions for treating Alzheimer's Disease and other neurological disorders by inhibiting expression and/or activity of ATF4. It further provides for diagnostic methods and reagents as well as assays to identify agents for the treatment of Alzheimer's Disease and other ATF4-related conditions.
    Type: Application
    Filed: September 12, 2008
    Publication date: June 11, 2009
    Inventors: Lloyd Greene, Michael Shelanski, Conrad Leung, Ottavio Valerio Vitolo
  • Methods for increasing learning and memory in amyloid-beta-related neurodegenerative disorders by increasing Uch-L1 activity and methods for identifying enhancers of Uch-L1 activity
    Publication number: 20070071724
    Abstract: The invention is directed to methods for increasing learning and memory in a subject with a neuropathological condition, specifically a condition related to elevated beta-amyloid deposition, the method comprising administering to the subject an effective amount of a compound capable of increasing the activity of Uch-L1. The invention is also directed to screening methods for identifying compounds that enhance the activity of the proteasome system, Uch-L1, or both.
    Type: Application
    Filed: June 29, 2006
    Publication date: March 29, 2007
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Ottavio Arancio, Michael Shelanski, Bing Gong