Abstract: The invention relates to a bioactive bone repair substrate comprising granules obtainable by or obtained from a set solid state mixture of a calcium phosphate based bone repair matrix and a bioactive material, preferably granules having an average diameter between 25 and 10,000 ?m.

Abstract: A delivery system for high viscosity material includes a cannula having an axis, an opening at a first end thereof, and an opening at a second end thereof. A dispenser includes a body member having a reservoir, a first opening at a first end thereof in fluid communication with the first end of the cannula; and a second opening at a second end thereof. A first transfer member has an aperture extending axially therethrough and is slidably received in the reservoir of the body member. A second transfer member has an aperture extending axially therethrough and is slidably received in the aperture of the first transfer member. A third transfer member is slidably received in the aperture in the second transfer member.

Abstract: A minimally invasive high viscosity material delivery system having a cannula associated with a dispenser for dispensing a high viscosity material out of the cannula, a body member having a first opening that is in communication with the cannula, a reservoir for receiving the high viscosity material, and a second opening associated with a transfer member for pushing the high viscosity material from the body member into the cannula via the first opening. The transfer member is in communication with the second opening. The cannula and the body member are connected in a non-linear angle. Also disclosed is a method of using such system.