Patents by Inventor Michael Siegel

Michael Siegel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12209040
    Abstract: In producing ethanol suitable for alcoholic beverages or fuels, the separation of stillage involves a complicated treatment system necessary to meet stringent air emissions standards and effluent discharge limits. High water content of stillage creates a difficult process mass flow balance configuration resulting in a large power demand and footprint. The present invention simplifies the production and usage of valuable stillage by-products and reduces net energy consumption and emissions to zero with a novel system and method involving a step sequence of: a solid liquid separation; at least one digester arrangement; a closed gas separation system; algae grow nutrient up-take system; a nutrient separation system; an ultra-filtration water system enabling the off-take by-products to be used by the system and an off-take market for the by-products and its purified water. All produced by-products including carbon dioxide (CO2) and methane (CH4) are used in the system or exported as products.
    Type: Grant
    Filed: June 17, 2024
    Date of Patent: January 28, 2025
    Inventors: Stanley Michael Siegel, Mark E. Ward, C. George Bower
  • Publication number: 20240417302
    Abstract: In producing ethanol suitable for alcoholic beverages or fuels, the separation of stillage involves a complicated treatment system necessary to meet stringent air emissions standards and effluent discharge limits. High water content of stillage creates a difficult process mass flow balance configuration resulting in a large power demand and footprint. The present invention simplifies the production and usage of valuable stillage by-products and reduces net energy consumption and emissions to zero with a novel system and method involving a step sequence of: a solid liquid separation; at least one digester arrangement; a closed gas separation system; algae grow nutrient up-take system; a nutrient separation system; an ultra-filtration water system enabling the off-take by-products to be used by the system and an off-take market for the by-products and its purified water. All produced by-products including carbon dioxide (CO2) and methane (CH4) are used in the system or exported as products.
    Type: Application
    Filed: June 17, 2024
    Publication date: December 19, 2024
    Inventors: Stanley Michael Siegel, Mark E. Ward, C. George Bower
  • Patent number: 12019060
    Abstract: An Ussing chamber assembly for assessing a tissue sample and for receiving a first fluid and a second fluid during such assessment is disclosed. The Ussing chamber assembly includes an Ussing chamber configured to be separated by the tissue sample into a first chamber portion and a second chamber portion. The assembly includes a first channel in fluidic communication with the first chamber portion, a second channel in fluidic communication with the second chamber portion, and at least three electrical conductors in fluidic communication with the first chamber portion.
    Type: Grant
    Filed: April 8, 2021
    Date of Patent: June 25, 2024
    Assignee: Colorado State University Research Foundation
    Inventors: Thomas W. Chen, Caleb R. Begly, Michael Siegel
  • Patent number: 11644410
    Abstract: The present invention provides systems, devices, and methods for point-of-care and/or distributed testing services. The methods and devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device can be modified to allow for more flexible and robust use with the disclosed methods for a variety of medical, laboratory, and other applications. The systems, devices, and methods of the present invention can allow for effective use of samples by improved sample preparation and analysis.
    Type: Grant
    Filed: December 28, 2020
    Date of Patent: May 9, 2023
    Assignee: Labrador Diagnostics LLC
    Inventors: Anthony J. Nugent, Daniel L. Young, Elizabeth A. Holmes, Michael Siegel, Ryan Wistort
  • Publication number: 20210333127
    Abstract: In one nonlimiting example, an automated system is provided for separating one or more components in a biological fluid, wherein the system comprises: (a) a centrifuge comprising one or more bucket configured to receive a container to effect said separating of one or more components in a fluid sample; and (b) the container, wherein the container includes one or more shaped feature that is complementary to a shaped feature of the bucket.
    Type: Application
    Filed: April 12, 2021
    Publication date: October 28, 2021
    Inventors: Elizabeth A. Holmes, Daniel Young, Timothy Smith, Scott Ridel, John Kent Frankovich, Michael Siegel
  • Publication number: 20210318286
    Abstract: An Ussing chamber assembly for assessing a tissue sample and for receiving a first fluid and a second fluid during such assessment is disclosed. The Ussing chamber assembly includes an Ussing chamber configured to be separated by the tissue sample into a first chamber portion and a second chamber portion. The assembly includes a first channel in fluidic communication with the first chamber portion, a second channel in fluidic communication with the second chamber portion, and at least three electrical conductors in fluidic communication with the first chamber portion.
    Type: Application
    Filed: April 8, 2021
    Publication date: October 14, 2021
    Applicant: Colorado State University Research Foundation
    Inventors: Thomas W. Chen, Caleb R. Begly, Michael Siegel
  • Publication number: 20210223163
    Abstract: The present invention provides systems, devices, and methods for point-of-care and/or distributed testing services. The methods and devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device can be modified to allow for more flexible and robust use with the disclosed methods for a variety of medical, laboratory, and other applications. The systems, devices, and methods of the present invention can allow for effective use of samples by improved sample preparation and analysis.
    Type: Application
    Filed: December 28, 2020
    Publication date: July 22, 2021
    Applicant: Labrador Diagnostics LLC
    Inventors: Anthony J. NUGENT, Daniel L. YOUNG, Elizabeth A. HOLMES, Michael SIEGEL, Ryan WISTORT
  • Patent number: 10876956
    Abstract: The present invention provides systems, devices, and methods for point-of-care and/or distributed testing services. The methods and devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device can be modified to allow for more flexible and robust use with the disclosed methods for a variety of medical, laboratory, and other applications. The systems, devices, and methods of the present invention can allow for effective use of samples by improved sample preparation and analysis.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: December 29, 2020
    Assignee: Labrador Diagnostics LLC
    Inventors: Anthony J. Nugent, Daniel L. Young, Elizabeth A. Holmes, Michael Siegel, Ryan Wistort
  • Patent number: 10780387
    Abstract: The invention provides a system and method that applies novel algorithms and compositions for efficiently adjusting compression, unit turn down, pressure and flows of a pressure swing adsorption unit. The present invention also reduces overall horsepower, increases unit's product gas recovery, maximizes product gas quality and allows for non-disturbance of upstream and downstream equipment in regard to pressure and flow oscillations. Raw gas streams addressed include methane (CH4), nitrogen (N2), oxygen (O2), carbon dioxide (CO2), water (H2O), Hydrogen Sulfide (H2S) and non-methane organic compounds (NMOC) gases/vapors. The invention incorporates a CO2 and H2O trim units and provides a VPSA N2 and O2 rejection section.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: September 22, 2020
    Assignee: ARC TECHNOLOGIES CORP.
    Inventor: Stanley Michael Siegel
  • Patent number: 9971855
    Abstract: A method for determining and or monitoring at least one process- and/or system specific parameter in automation technology. An oscillatable system is provided, which interacts with a medium located in a container, wherein the oscillatable system is excited to oscillate via a real input signal, wherein the real output signal of the oscillatable system is ascertained, wherein the real output signal is digitized and a real output sequence yu(k) is produced. The real input signal is digitized and a digital input sequence (u(k)) is produced, wherein the digital input sequence (u(k)) is fed to a function block (model), which provides at least one mathematical model of the oscillatable system in interaction with the medium. The mathematical model is defined by a number of process- and/or system specific parameters, wherein via the mathematical model a virtual output sequence (ym(k)) is produced, wherein the virtual output sequence ym(k) is compared with the real output sequence yu(k).
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: May 15, 2018
    Assignee: Endress + Hauser GmbH + Co. KG
    Inventors: Tobias Brengartner, Gerd Bechtel, Michael Siegel
  • Publication number: 20170363536
    Abstract: The present invention provides systems, devices, and methods for point-of-care and/or distributed testing services. The methods and devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device can be modified to allow for more flexible and robust use with the disclosed methods for a variety of medical, laboratory, and other applications. The systems, devices, and methods of the present invention can allow for effective use of samples by improved sample preparation and analysis.
    Type: Application
    Filed: May 2, 2017
    Publication date: December 21, 2017
    Inventors: Anthony J. Nugent, Daniel L. Young, Elizabeth A. Holmes, Michael Siegel, Ryan Wistort
  • Patent number: 9677993
    Abstract: The present invention provides systems, devices, and methods for point-of-care and/or distributed testing services. The methods and devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device can be modified to allow for more flexible and robust use with the disclosed methods for a variety of medical, laboratory, and other applications. The systems, devices, and methods of the present invention can allow for effective use of samples by improved sample preparation and analysis.
    Type: Grant
    Filed: July 1, 2015
    Date of Patent: June 13, 2017
    Assignee: Theranos, Inc.
    Inventors: Anthony Nugent, Daniel Young, Elizabeth A. Holmes, Michael Siegel, Ryan Wistort
  • Patent number: 9383115
    Abstract: The invention relates to fresh air ventilation devices adapted for use with air conditioners (ACs) and/or heaters. In operation, the device supplements the recirculating air of the AC/heater with fresh air drawn from outside of the building.
    Type: Grant
    Filed: March 16, 2010
    Date of Patent: July 5, 2016
    Assignee: Ice Air, LLC
    Inventors: Moshe Michael Siegel, Fredric Nadel, Qianli Fu
  • Publication number: 20160188766
    Abstract: A method for determining and or monitoring at least one process- and/or system specific parameter in automation technology. An oscillatable system is provided, which interacts with a medium located in a container, wherein the oscillatable system is excited to oscillate via a real input signal, wherein the real output signal of the oscillatable system is ascertained, wherein the real output signal is digitized and a real output sequence yu(k) is produced. The real input signal is digitized and a digital input sequence (u(k)) is produced, wherein the digital input sequence (u(k)) is fed to a function block (model), which provides at least one mathematical model of the oscillatable system in interaction with the medium. The mathematical model is defined by a number of process- and/or system specific parameters, wherein via the mathematical model a virtual output sequence (ym(k)) is produced, wherein the virtual output sequence ym(k) is compared with the real output sequence yu(k).
    Type: Application
    Filed: December 6, 2013
    Publication date: June 30, 2016
    Applicant: Endress + Hauser GmbH + Co., KG
    Inventors: Tobias BRENGARTNER, Gerd BECHTEL, Michael SIEGEL
  • Patent number: 9314164
    Abstract: The present invention, in one aspect, relates to a method for distinguishing between possible adenomatous and hyperplastic polyps using what is referred to as “Early Increase in microvascular Blood Supply” (EIBS) that exists in tissues that are close to, but are not themselves, the abnormal tissue.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: April 19, 2016
    Assignees: NORTHWESTERN UNIVERSITY, NORTHSHORE UNIVERSITY HEALTH SYSTEM
    Inventors: Vadim Backman, Hemant Roy, Young L. Kim, Michael Siegel, Vladimir Turzhitsky
  • Publication number: 20160047834
    Abstract: The present invention provides systems, devices, and methods for point-of-care and/or distributed testing services. The methods and devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device can be modified to allow for more flexible and robust use with the disclosed methods for a variety of medical, laboratory, and other applications. The systems, devices, and methods of the present invention can allow for effective use of samples by improved sample preparation and analysis.
    Type: Application
    Filed: July 1, 2015
    Publication date: February 18, 2016
    Inventors: Anthony Nugent, Daniel Young, Elizabeth A. Holmes, Michael Siegel, Ryan Wistort
  • Publication number: 20150198465
    Abstract: In one nonlimiting example, an automated system is provided for separating one or more components in a biological fluid, wherein the system comprises: (a) a centrifuge comprising one or more bucket configured to receive a container to effect said separating of one or more components in a fluid sample; and (b) the container, wherein the container includes one or more shaped feature that is complementary to a shaped feature of the bucket.
    Type: Application
    Filed: January 16, 2015
    Publication date: July 16, 2015
    Inventors: Elizabeth A. Holmes, Daniel L. Young, Timothy Smith, Scott Ridel, John Kent Frankovich, Michael Siegel
  • Patent number: 8955377
    Abstract: A method and an apparatus for determining or monitoring a predetermined fill level, a phase boundary or a density of a medium in a container with an oscillatable unit. The oscillatable unit is placed at the height of the predetermined fill level and is excited to oscillate successively with discrete exciter frequencies following one another in a frequency scanning operation (sweep) within a predeterminable frequency band in the working range of the oscillatable unit. The corresponding oscillations of the oscillatable unit are received in the form of received signals; wherein that exciter frequency is ascertained in the frequency scanning operation, at which the oscillatable unit oscillates with an oscillation frequency, which has a predetermined phase shift between the transmission signal and the received signal; and wherein the transmitting/receiving unit excites the oscillatable unit to oscillate with the ascertained oscillation frequency.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: February 17, 2015
    Assignee: Endress + Hauser GmbH + Co. KG
    Inventors: Martin Hortenbach, Martin Urban, Dietmar Frühauf, Tobias Brengartner, Frank Ruhnau, Michael Siegel
  • Publication number: 20140373607
    Abstract: Apparatus for determining and/or monitoring at least one process variable of a medium in a container, comprising: a mechanically oscillatable unit; an electromechanical transducer unit, which has at least one piezoelectric or inductive, transducer element, which excites the oscillatable unit by means of an exciter signal to execute mechanical oscillations and which receives oscillations from the oscillatable unit and converts them into an electrical, received signal; a reference element having a first component of electrically adjustable size, wherein the reference element is connected in parallel with the electromechanical transducer unit and supplied with the same exciter signal and produces a reference signal uninfluenced by the oscillations of the oscillatable unit, and an electronics unit, which extracts a wanted signal from the received signal and the reference signal and, based on the wanted signal, determines and/or monitors the process variable.
    Type: Application
    Filed: November 22, 2012
    Publication date: December 25, 2014
    Inventors: Max Bauer, Tobias Brengartner, Martin Urban, Michael Siegel
  • Patent number: 8869597
    Abstract: A method for operating an apparatus which has an oscillatable unit. The oscillatable unit is excited to oscillate by means of a first frequency sweep within a predetermined frequency band with successive, discrete exciter frequencies of increasing or decreasing frequency. A first exciter frequency is ascertained, in the case of which, during the first frequency sweep, at least one predeterminable criterion is fulfilled. The oscillatable unit is excited by means of a second frequency sweep, wherein the frequency band, compared with the first frequency sweep, is run through in the opposite direction. A second exciter frequency is ascertained, in the case of which, during the second frequency sweep, the at least one predeterminable criterion is fulfilled. From the first exciter frequency and the second exciter frequency, via formation of an average, a measuring frequency for determining and/or monitoring at least one process variable is determined.
    Type: Grant
    Filed: May 3, 2012
    Date of Patent: October 28, 2014
    Assignee: Endress + Hauser GmbH + Co. KG
    Inventors: Tobias Brengartner, Martin Urban, Michael Siegel