Abstract: The present invention provides a novel treatment of alopecia areate. The problem to be solved by the invention is to provide a new pharmaceutical use of 3-[(3S,4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile. A therapeutic or preventive agent for alopecia areata, containing 3-[(3S,4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile as an active ingredient.

Abstract: The present invention provides a novel treatment of alopecia areate. The problem to be solved by the invention is to provide a new pharmaceutical use of 3-[(3S,4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile. A therapeutic or preventive agent for alopecia areata, containing 3-[(3S,4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile as an active ingredient.

Abstract: A reduced fogging mirror configured to be removably mounted to a surface such as a shower surface is disclosed. The reduced fogging mirror includes a reflective substrate and a foam backing attached to the reflective substrate. The foam backing is used as an insulator to keep the temperature of the reflective surface from fluctuating. This allows the reflective surface to maintain a temperature similar to a shower's water and steam, reducing the fogging on the reflective substrate. The foam backing is also configured to retain water such that the reduced fogging mirror can be adhered to the shower surface using water tension between the foam backing and the shower surface.

Abstract: A reduced fogging mirror configured to be removably mounted to a surface such as a shower surface is disclosed. The reduced fogging mirror includes a reflective substrate and a foam backing attached to the reflective substrate. The foam backing is used as an insulator to keep the temperature of the reflective surface from fluctuating. This allows the reflective surface to maintain a temperature similar to a shower's water and steam, reducing the fogging on the reflective substrate. The foam backing is also configured to retain water such that the reduced fogging mirror can be adhered to the shower surface using water tension between the foam backing and the shower surface.

Abstract: The present invention provides combinations of compounds of formula (I) and other therapeutic agents for the treatment of PPAR related diseases.

Abstract: Compounds of the general structural formula and use of the compounds and salts and solvates thereof, as therapeutic agents.

Abstract: A compound of formula (I) or a pharmaceutically acceptable salt, solvate, or hydrolysable ester thereof, wherein:

Abstract: Compounds of the general structural formula 1